Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Dravet Syndrome Clinical Trials
Dravet Syndrome clinical trials are recruiting across 29 cities. Here are the cities with the most active studies:
Dravet Syndrome Trial Phases
8 research organizations are sponsoring dravet syndrome trials.
About Dravet Syndrome
Dravet syndrome is a rare, severe form of epilepsy that begins in the first year of life with prolonged seizures often triggered by fever. It is usually caused by mutations in the SCN1A gene. Treatment includes specific antiseizure medications, avoiding certain drugs that can worsen seizures, and investigational gene therapies.
Clinical trials are advancing new treatments for dravet syndrome. Currently, 8 studies are recruiting a combined 625 participants across the United States. Research is being conducted by 8 organizations including Stoke Therapeutics, Inc, Longboard Pharmaceuticals, Epygenix and 5 others.
2026 Dravet Syndrome Research Landscape
As of July 2026, the dravet syndrome clinical trial landscape includes 8 actively recruiting studies across 29 cities in the United States. These studies are collectively seeking 625 participants, with an average enrollment target of 78 per study.
The research spans multiple phases of development: 3 studies are in PHASE3, 2 studies are in PHASE1, 2 studies are in PHASE2, 2 studies are in PHASE4. The presence of Phase 3 trials indicates that some dravet syndrome treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 8 different organizations, including Stoke Therapeutics, Inc, Longboard Pharmaceuticals, Epygenix, Encoded Therapeutics, Cook Children's Health Care System, and 3 others.
Geographically, dravet syndrome trials are most concentrated in San Francisco, California (4 trials); Aurora, Colorado (4 trials); Little Rock, Arkansas (3 trials); Los Angeles, California (3 trials); Miami, Florida (3 trials) and 7 other cities.
Featured Dravet Syndrome Studies
Highlighted recruiting studies for dravet syndrome, selected by enrollment size and research scope.
A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
The purpose of the study is to evaluate the efficacy, safety, and tolerability of zorevunersen in Patients with Dravet syndrome.
A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
This (DEEp SEA Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DS. The study consists of 3 main phases: Screening, Titration period, and Maintenance period, followed by a Taper period and Follow-Up. Participants will be randomized to LP352 or placebo. ...
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
This is a multicenter, Phase 3, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of clemizole hydrochloride (EPX-100) as adjunctive therapy in children and adult participants with Dravet syndrome (DS).
Frequently Asked Questions About Dravet Syndrome Clinical Trials
Are there dravet syndrome clinical trials near me?
Yes, there are 8 dravet syndrome clinical trials currently recruiting across 29+ cities in the United States, including San Francisco, California; Aurora, Colorado; Little Rock, Arkansas. Browse the studies above to find one at a location convenient for you.
How do I join a dravet syndrome clinical trial?
To join a dravet syndrome clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are dravet syndrome clinical trials free?
Yes, participation in dravet syndrome clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of dravet syndrome treatments are being studied?
Current dravet syndrome clinical trials are testing a range of approaches across PHASE3 (3 studies), PHASE1 (2 studies), PHASE2 (2 studies), PHASE4 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 8 research organizations.
Is it safe to participate in dravet syndrome clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 19, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 19, 2026 · Data from ClinicalTrials.gov