Ann Arbor, MICHIGAN7 Active Studies

Prostate Cancer Clinical Trials in Ann Arbor, MICHIGAN

Find 7 actively recruiting prostate cancer clinical trials in Ann Arbor, MICHIGAN. Connect with local research sites and explore new treatment options.

7
Active Trials
5
Sponsors
1,211
Enrolling

Recruiting Prostate Cancer Studies in Ann Arbor

RecruitingAnn Arbor, MICHIGANNCT04787744

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-...

464 participants
VA Office of Research and Development
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RecruitingAnn Arbor, MICHIGANNCT04812366

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be...

315 participants
University of British Columbia
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RecruitingAnn Arbor, MICHIGANNCT04986423

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

This is an open-label, randomized, Phase 2b study of ZEN003694 in combination with enzalutamide vs. enzalutamide monotherapy in patients with mCRPC who have progressed on prior abiraterone by PCWG3 cr...

200 participants
Zenith Epigenetics
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RecruitingAnn Arbor, MICHIGANNCT04038502

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

This is an unblinded, randomized clinical study comparing the efficacy of DNA damaging chemotherapy using carboplatin, to standard of care therapy for patients who have metastatic castrate resistant p...

100 participants
VA Office of Research and Development
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RecruitingAnn Arbor, MICHIGANNCT06228053

Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer

The goal of this clinical trial is to study the combination of SX-682 plus enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC) who have failed abiraterone....

53 participants
Syntrix Biosystems, Inc.
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RecruitingAnn Arbor, MICHIGANNCT04104893

A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation

The primary objective is to assess the activity and efficacy of pembrolizumab, a checkpoint inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either ...

40 participants
VA Office of Research and Development
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RecruitingAnn Arbor, MICHIGANNCT06616155

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

This phase I/II tests the safety, side effects and best dose of ruxolitinib in combination with enzalutamide and how well it works in treating patients with prostate cancer that remains despite blocki...

39 participants
University of Michigan Rogel Cancer Center
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About Prostate Cancer Clinical Trials in Ann Arbor

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 7 prostate cancer clinical trials recruiting participants in Ann Arbor, MICHIGAN. These studies are seeking a combined 1,211 participants. Research is being sponsored by VA Office of Research and Development, University of British Columbia, Zenith Epigenetics and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Ann Arbor — FAQ

Are there prostate cancer clinical trials in Ann Arbor?

Yes, there are 7 prostate cancer clinical trials currently recruiting in Ann Arbor, MICHIGAN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Ann Arbor?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Ann Arbor research site will contact you about next steps.

Are clinical trials in Ann Arbor free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Ann Arbor studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 7 active trials in Ann Arbor are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated March 2, 2026 from ClinicalTrials.gov