Atlanta, GEORGIA14 Active Studies

Breast Cancer Clinical Trials in Atlanta, GEORGIA

Find 14 actively recruiting breast cancer clinical trials in Atlanta, GEORGIA. Connect with local research sites and explore new treatment options.

14
Active Trials
14
Sponsors
2,492
Enrolling

Recruiting Breast Cancer Studies in Atlanta

RecruitingAtlanta, GEORGIANCT05696626

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

The goal of this clinical trial is to assess the efficacy, safety and tolerability of the combination of lasofoxifene and abemaciclib compared to fulvestrant and abemaciclib for the treatment of pre- ...

500 participants
Sermonix Pharmaceuticals Inc.
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RecruitingAtlanta, GEORGIANCT06075953

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

The goal of this trial is to see if active surveillance monitoring and hormonal therapy in patients diagnosed with ductal cell carcinoma in situ (DCIS), an early stage of breast cancer, can be an effe...

400 participants
QuantumLeap Healthcare Collaborative
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RecruitingAtlanta, GEORGIANCT04569747

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer

This research study is studying a combination of HER2-directed therapies (trastuzumab and pertuzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. Th...

375 participants
Dana-Farber Cancer Institute
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RecruitingAtlanta, GEORGIANCT05856773

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

The purpose of this research study is to learn more about the effects of using proton radiation therapy delivered over a shorter course of treatment (3 weeks) compared with a longer, standard course o...

276 participants
Proton Collaborative Group
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RecruitingAtlanta, GEORGIANCT04851613

Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer

Study LAE205INT3101 is a Phase Ib/III study to evaluate the efficacy and safety of the combination therapy with afuresertib plus fulvestrant (afuresertib/placebo plus fulvestrant in Phase III) in pati...

256 participants
Laekna Limited
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RecruitingAtlanta, GEORGIANCT05735080

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio (Incyclix) is developing INX-315 as an oral, small molecule inhibitor of cyclin dependent kinase 2 (CDK2) for the treatment of human cancers. This first-in-human study is designed to eval...

150 participants
Incyclix Bio
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RecruitingAtlanta, GEORGIANCT06590857

Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.

Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs....

124 participants
RayzeBio, Inc.
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RecruitingAtlanta, GEORGIANCT06926920

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

The goal of this clinical study is to learn more about the study drug sacituzumab govitecan-hziy (SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNB...

100 participants
Gilead Sciences
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RecruitingAtlanta, GEORGIANCT06263543

Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBC

The purpose of this research study is to see if the medication sacituzumab govitecan (SG) is effective at the currently approved dose and schedule in people who have previously received trastuzumab de...

75 participants
Reshma L. Mahtani, D.O.
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RecruitingAtlanta, GEORGIANCT04567420

DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

A randomized, Phase II trial of circulating tumor DNA-guided second line Adjuvant therapy for high Residual risk, Estrogen Receptor positive, HER-2 negative breast cancer (DARE)...

70 participants
Criterium, Inc.
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RecruitingAtlanta, GEORGIANCT05570253

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treatment for people with TNBC and metabolic d...

55 participants
Memorial Sloan Kettering Cancer Center
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RecruitingAtlanta, GEORGIANCT06460298

ProAgio in Combination With Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer

This is a Phase I/II Trial Evaluating the Safety and Efficacy of ProAgio, an anti- αvβ3 Integrin Cytotoxin, in Combination with Gemcitabine in Patients with Metastatic Triple Negative Breast Cancer...

51 participants
ProDa BioTech, LLC
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RecruitingAtlanta, GEORGIANCT05919108

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

This phase II trial tests how well neratinib prior to the primary treatment (neoadjuvant) works in treating patients with stage I-III HER2 mutated lobular breast cancers. Neratinib is in a class of me...

30 participants
Vanderbilt-Ingram Cancer Center
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RecruitingAtlanta, GEORGIANCT03990896

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation....

30 participants
Massachusetts General Hospital
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About Breast Cancer Clinical Trials in Atlanta

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 14 breast cancer clinical trials recruiting participants in Atlanta, GEORGIA. These studies are seeking a combined 2,492 participants. Research is being sponsored by Sermonix Pharmaceuticals Inc., QuantumLeap Healthcare Collaborative, Dana-Farber Cancer Institute and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Atlanta — FAQ

Are there breast cancer clinical trials in Atlanta?

Yes, there are 14 breast cancer clinical trials currently recruiting in Atlanta, GEORGIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Atlanta?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Atlanta research site will contact you about next steps.

Are clinical trials in Atlanta free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Atlanta studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 14 active trials in Atlanta are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov