Baltimore, MARYLAND12 Active Studies

Prostate Cancer Clinical Trials in Baltimore, MARYLAND

Find 12 actively recruiting prostate cancer clinical trials in Baltimore, MARYLAND. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
2,778
Enrolling

Recruiting Prostate Cancer Studies in Baltimore

RecruitingBaltimore, MARYLANDNCT03574571

A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer

The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetaxel alone. Earlier studies helped show that the comb...

738 participants
Memorial Sloan Kettering Cancer Center
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RecruitingBaltimore, MARYLANDNCT04787744

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-...

464 participants
VA Office of Research and Development
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RecruitingBaltimore, MARYLANDNCT05125016

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer

This study is researching an investigational drug called REGN4336. Some participants may receive additional investigational drugs in combination with REGN4336. These additional drugs include REGN5678,...

370 participants
Regeneron Pharmaceuticals
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RecruitingBaltimore, MARYLANDNCT06873581

Pivotal Study of Voro Urologic Scaffold

The objective of this study is to compare safety and effectiveness of the Voro Urologic Scaffold in adult men undergoing robotic assisted radical prostatectomy as compared to control arm. The study i...

266 participants
Levee Medical, Inc.
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RecruitingBaltimore, MARYLANDNCT06353386

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Substudy 01A is part of a larger research study that is testing experimental treatments for metastatic castration-resistant prostate cancer (mCRPC). The larger study is the umbrella study (U01). The ...

220 participants
Merck Sharp & Dohme LLC
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RecruitingBaltimore, MARYLANDNCT06014255

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

This study evaluates the efficacy, anti-tumor effect, and immunogenicity of neoadjuvant enoblituzumab given before radical prostatectomy. Patients will be randomized to enoblituzumab for a total of 12...

219 participants
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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RecruitingBaltimore, MARYLANDNCT04363164

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

Asymptomatic men without pain due to prostate cancer progressing with metastatic CRPC after treatment with combination or sequential ADT + Abi will be treated on a randomized, open label study to dete...

150 participants
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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RecruitingBaltimore, MARYLANDNCT05682443

ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC

In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The ...

141 participants
OncoC4, Inc.
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RecruitingBaltimore, MARYLANDNCT05223803

TERPS Trial for De Novo Oligometastic Prostate Cancer

This research is being done to see if we can improve the outcome of prostate cancer patients who present with metastatic lesions at initial diagnosis....

122 participants
University of Maryland, Baltimore
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RecruitingBaltimore, MARYLANDNCT05498272

Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations

Phase 2 open-label, single-arm clinical trial evaluating the efficacy and safety of neoadjuvant olaparib + LHRH agonist administered for 6 months prior to radical prostatectomy (RP) in men with unfavo...

32 participants
Rana McKay, MD
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RecruitingBaltimore, MARYLANDNCT05691465

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

This phase II trial studies how well lutetium Lu 177 dotatate works in treating patients with prostate cancer with neuroendocrine differentiation that has spread to other places in the body (metastati...

30 participants
National Cancer Institute (NCI)
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RecruitingBaltimore, MARYLANDNCT05458544

[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application

Phase 1: The objective of the Phase 1 part of the clinical trial is to verify safety and tolerability (dose-limiting toxicity \[DLT\], maximum tolerated dose \[MTD\]) of a single 3.7 Giga-Becquerel (G...

26 participants
FutureChem
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About Prostate Cancer Clinical Trials in Baltimore

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 12 prostate cancer clinical trials recruiting participants in Baltimore, MARYLAND. These studies are seeking a combined 2,778 participants. Research is being sponsored by Memorial Sloan Kettering Cancer Center, VA Office of Research and Development, Regeneron Pharmaceuticals and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Baltimore — FAQ

Are there prostate cancer clinical trials in Baltimore?

Yes, there are 12 prostate cancer clinical trials currently recruiting in Baltimore, MARYLAND. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 12 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated March 2, 2026 from ClinicalTrials.gov