19 Multiple Sclerosis Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Multiple Sclerosis Studies in Baltimore

NCT04473794Recruiting

Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts

The aims of this study are to determine the natural history of pancreatic cysts and to propose and prospectively validate a diagnostic approach and model for prediction of mucinous versus non-mucinous...

Baltimore, MD5,000 participantsJohns Hopkins University

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NCT00900198Recruiting

Collection of Tissue Samples for Cancer Research

Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this tissue procurement protocol for collection ...

Baltimore, MD5,000 participantsNational Cancer Institute (NCI)

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NCT06441617Recruiting

Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis

CAFE-MS will assess the effectiveness of two online programs for fatigue in multiple sclerosis (MS). Although they differ, both of these online programs contain information about MS and fatigue intend...

Baltimore, MDNA2,000 participantsAccelerated Cure Project for Multiple Sclerosis

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NCT06131840Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one p...

Baltimore, MDPHASE1914 participantsSeagen, a wholly owned subsidiary of Pfizer

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NCT04429087Recruiting

A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

This study is open to adults with small cell lung cancer and other neuroendocrine cancers that are positive for the tumour marker delta-like 3 (DLL3). The study is in people with advanced cancer for w...

Baltimore, MDPHASE1300 participantsBoehringer Ingelheim

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NCT06034002Recruiting

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

This study is being conducted to evaluate the safety, tolerability, dose-limiting toxicity (DLT) and determine the maximum tolerated dose (MTD) and/or recommended dose(s) for expansion (RDE) of INCA03...

Baltimore, MDPHASE1290 participantsIncyte Corporation

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NCT04794322Recruiting

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

The study aims to develop a test for early detection of ovarian cancer using DNA from a growth involving the ovary found in a washing of the uterus (womb), and proteins found in the blood. The samples...

Baltimore, MD250 participantsMassachusetts General Hospital

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NCT03391778Recruiting

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion....

Baltimore, MDPHASE1250 participantsUSWM CT, LLC

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NCT07441694Recruiting

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

This study will be conducted to determine the safety, tolerability, dose-limiting toxicity (DLT)s, and maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE)s of INCA036978 administe...

Baltimore, MDPHASE1218 participantsIncyte Corporation

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NCT07074886Recruiting

A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

The main purpose of this study is to assess the bioequivalence of ocrelizumab SC test formulation to the marketed ocrelizumab SC reference formulation in participants with either relapsing multiple sc...

Baltimore, MDPHASE2182 participantsHoffmann-La Roche

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NCT07497399Recruiting

Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis

The goal of this clinical trial is to evaluate if the study drug will reduce brain and retinal atrophy by reducing inflammation and subsequently slowing neurodegeneration in people with Multiple Scler...

Baltimore, MDPHASE2120 participantsJohns Hopkins University

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NCT07008118Recruiting

A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms

This study is being conducted to evaluate the safety and tolerability of INCA035784 in participants with myeloproliferative neoplasms....

Baltimore, MDPHASE1120 participantsIncyte Corporation

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NCT06482515Recruiting

Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue

Cancer-related fatigue affects at least 30-90% of patients with cancer, depending on the type of cancer and their treatment(s) (e.g., chemotherapy, radiation). It is not relieved by sleep or rest, and...

Baltimore, MDPHASE296 participantsUniversity of Maryland, Baltimore

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NCT07667322Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis

The main purpose of this study is to evaluate the safety and tolerability of the ocrelizumab subcutaneous (SC) test formulation in participants with multiple sclerosis (MS). The study consists of two ...

Baltimore, MDPHASE175 participantsHoffmann-La Roche

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NCT06796504Recruiting

The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

The MS pilot study will assess the safety and investigate the remyelinating effects of the SetPoint System (study device) in adult patients with patients diagnosed with relapsing-remitting multiple sc...

Baltimore, MDNA60 participantsSetPoint Medical Corporation

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NCT07389590Recruiting

Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis

The proposed study is a pilot study of ublituximab involving people with multiple sclerosis (MS) who are experiencing a "wearing off" phenomenon (return or worsening of MS-related symptoms) while bein...

Baltimore, MDPHASE450 participantsJohns Hopkins University

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NCT06170970Recruiting

Solriamfetol for the Treatment of Multiple Sclerosis Fatigue

Fatigue is a prevalent and disabling symptom in Multiple Sclerosis (MS), affecting up to 90% of patients. Current treatments, including off-label prescriptions of wake-promoting agents, have shown lim...

Baltimore, MDPHASE246 participantsJohns Hopkins University

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NCT06864936Recruiting

Exploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple Sclerosis

The purpose of the research study is to explore new retinal imaging biomarkers of immune cell activity in MS during use of ublituximab (Briumvi) treatment. A biomarker is a biological molecule found i...

Baltimore, MDNA30 participantsUniversity of Maryland, Baltimore

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NCT04123314Recruiting

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

This open-label pilot study examines whether the hallucinogenic drug, psilocybin, given under supportive conditions, is safe and effective for depression in people with Mild Cognitive Impairment (MCI)...

Baltimore, MDEARLY_PHASE120 participantsJohns Hopkins University

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About Multiple Sclerosis Clinical Trials in Baltimore

Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks the protective covering of nerve fibers, causing communication problems between the brain and body. Symptoms vary widely and can include vision problems, fatigue, and mobility issues. Disease-modifying therapies have significantly improved outcomes.

There are currently 19 multiple sclerosis clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 15,021 participants. Research is being sponsored by Johns Hopkins University, National Cancer Institute (NCI), Accelerated Cure Project for Multiple Sclerosis and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Sclerosis Clinical Trials in Baltimore — FAQ

Are there multiple sclerosis clinical trials in Baltimore?

Yes, there are 19 multiple sclerosis clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What multiple sclerosis treatments are being tested?

The 19 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for multiple sclerosis.

Data updated July 18, 2026 from ClinicalTrials.gov