45 Myalgic Encephalomyelitis Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Myalgic Encephalomyelitis Studies in Baltimore

NCT06058234Recruiting

Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study

The Anti-Aβ mAb CED Study is a prospective, longitudinal coverage with evidence development (CED) study using clinical data, patient assessments, and administrative claims data of the Medicare populat...

Baltimore, MD8,680 participantsCenters for Medicare and Medicaid Services/ Coverage and Analysis Group

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NCT07015905Recruiting

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side) total knee replacement surgery. The aim...

Baltimore, MDPHASE32,000 participantsRegeneron Pharmaceuticals

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NCT07166094Recruiting

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

The purpose of this study is to compare how well Rina-S (GEN1184) works compared to treatment of physician's choice (paclitaxel or doxorubicin) that are considered standard medical care for the treatm...

Baltimore, MDPHASE3660 participantsGenmab

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NCT07184619Recruiting

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

This is a prospective, 12-week, randomized, double-blind, placebo-controlled study, designed to evaluate the efficacy, safety, and tolerability of a dose of evenamide of 15 mg bid, compared to placebo...

Baltimore, MDPHASE3400 participantsNewron Pharmaceuticals SPA

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NCT06863129Recruiting

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

The goal of this clinical trial is to find out if removing and replacing part of the hip bone works better than using metal hardware to stabilize the bone in patients whose cancer has spread to the hi...

Baltimore, MDNA334 participantsMichelle Ghert, MD

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NCT07154290Recruiting

A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

This study will evaluate two study drugs called ubamatamab and REGN7075, to see if they can help treat advanced or metastatic Non-Small Cell Lung Cancer (NSCLC), and sarilumab, to evaluate to see if i...

Baltimore, MDPHASE2300 participantsRegeneron Pharmaceuticals

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NCT06704594Recruiting

Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder

Premenstrual dysphoric disorder (PMDD) is a severe affective disorder impacting millions of women worldwide, thought to be due to altered sensitivity to hormone fluctuations across the menstrual cycle...

Baltimore, MDPHASE4288 participantsJohns Hopkins University

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NCT05219617Recruiting

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in ped...

Baltimore, MDPHASE3252 participantsSK Life Science, Inc.

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NCT05795634Recruiting

Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease

The goal of this clinical trial is to learn about how genetics and the response to stress predicts cognitive decline in individuals with mild cognitive impairment. The main question\[s\] it aims to a...

Baltimore, MDNA240 participantsJohns Hopkins University

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NCT06734351Recruiting

A Study to Assess Safety and Effectiveness of Injections of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Change of Mid-Face Volume

Facial fullness is often regarded as a characteristic feature of a youthful face. Chronic reduction of collagen, elastin, and glycosaminoglycans contribute to the facial volume loss that characterizes...

Baltimore, MDPHASE3231 participantsAbbVie

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NCT07205718Recruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

TAK-188 is a new medicine that targets a protein called CCR8, which is found on the surface of certain cells (Tregs) inside tumors. These cells can weaken the body's ability to fight cancer. TAK-188 m...

Baltimore, MDPHASE1223 participantsTakeda

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NCT06840496Recruiting

To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome

Primary Objective • To investigate the efficacy of treatment with oral Bionetide versus placebo in girls and women with Rett syndrome Key Secondary Objective • To investigate the efficacy of treatme...

Baltimore, MDPHASE3210 participantsBiomed Industries, Inc.

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NCT07038200Recruiting

A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous AOC 1020 for the Treatment of Facioscapulohumeral Muscular Dystrophy (FSHD)...

Baltimore, MDPHASE3200 participantsAvidity Biosciences, Inc.

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NCT05543681Recruiting

Clinical Trial on Agitation in Alzheimer's Dementia

The purpose of this study is to assess the efficacy of the oral medication IGC-AD1, a THC-based (Delta-9-Tetrahydrocannabinol) formulation administered twice a day on Agitation in patients with mild t...

Baltimore, MDPHASE2164 participantsIGC Pharma, LLC

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NCT05758701Recruiting

CT TAVR Abdomen Study

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search ...

Baltimore, MDPHASE4164 participantsUniversity of Maryland, Baltimore

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NCT06408662Recruiting

Remote Delivery of a Mindfulness-based Intervention for Tics

This research study is being done to compare a mindfulness-based intervention for tics (MBIT) to psychoeducation with relaxation and supportive therapy (PRST) for individuals with Tourette's syndrome ...

Baltimore, MDNA150 participantsJohns Hopkins University

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NCT06240728Recruiting

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2

NPX887 is a human, antagonistic immunoglobulin G1 (IgG1) monoclonal antibody targeting B7-H7 (HHLA2) that may potentiate an anti-tumor immune response. The goal of this first-in-human study is to lear...

Baltimore, MDPHASE1144 participantsNextPoint Therapeutics, Inc.

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NCT06847685Recruiting

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy...

Baltimore, MD140 participantsJohns Hopkins University

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NCT06366464Recruiting

A Study of Pitolisant in Patients With Prader-Willi Syndrome

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The ...

Baltimore, MDPHASE3134 participantsHarmony Biosciences Management, Inc.

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NCT04817618Recruiting

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

The Primary Completion Date and Study Completion Date have been updated to reflect completion of the adolescent cohort, which has been added to the protocol. The study is designed as a multicenter, r...

Baltimore, MDPHASE398 participantsNovartis Pharmaceuticals

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NCT06934538Recruiting

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

This is a phase I/IIA, first-in-human (FIH), two-part, open-label, multicenter study to characterize the safety, tolerability profile, and clinical efficacy of STC-1010 associated with GM-CSF and cycl...

Baltimore, MDPHASE190 participantsBrenus Pharma

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NCT07332091Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-rel...

Baltimore, MDPHASE284 participantsCSL Behring

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NCT05839912Recruiting

Excision of Lymph Node Trial (EXCILYNT) (Mel69)

The purpose of this study is to find out if removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing cancer from coming back in the same area of the lymph nod...

Baltimore, MDNA66 participantsCraig L Slingluff, Jr

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NCT03383575Recruiting

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

This phase II trial studies the side effects and how well azacitidine and enasidenib work in treating patients with IDH2-mutant myelodysplastic syndrome. Azacitidine and enasidenib may stop the growth...

Baltimore, MDPHASE263 participantsM.D. Anderson Cancer Center

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NCT07157254Recruiting

A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

The main goal of the study is to evaluate the safety and efficacy of GTX-102 in participants with Angelman syndrome....

Baltimore, MDPHASE260 participantsUltragenyx Pharmaceutical Inc

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NCT03949855Recruiting

Belimumab With Rituximab for Primary Membranous Nephropathy

The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete or partial remission (CR or PR) compared to rituxim...

Baltimore, MDPHASE258 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT04248569Recruiting

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

The primary objective of the trial is the safety and tolerability of administering a vaccine targeting the DNAJB1-PRKACA fusion kinase, in combination with nivolumab and ipilimumab in patients with un...

Baltimore, MDPHASE156 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT04601038Recruiting

Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)

CORT-X will examine if mitigation of stress-mediated pathogenesis of Alzheimer's disease (AD) is a feasible target for intervention in individuals at risk for this disease. This single-site (Baltimore...

Baltimore, MDPHASE252 participantsJohns Hopkins University

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NCT05795465Recruiting

A Study of GEn-1124 in Subjects with Acute Respiratory Distress Syndrome (ARDS)

GEn1E-1124-002 is a two-part Phase 2 study to evaluate the safety and tolerability of GEn-1124 in subjects with ARDS. Treatment with IV infusion dosing as early as possible after ARDS diagnosis. Subje...

Baltimore, MDPHASE252 participantsGEn1E Lifesciences

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NCT06430385Recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

The primary purpose of this study is to evaluate the safety and tolerability of ION440....

Baltimore, MDPHASE148 participantsIonis Pharmaceuticals, Inc.

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NCT05172245Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients ...

Baltimore, MDPHASE146 participantsNational Cancer Institute (NCI)

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NCT04789044Recruiting

Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury. PEG is s...

Baltimore, MDPHASE240 participantsMajor Extremity Trauma Research Consortium

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NCT05705024Recruiting

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of...

Baltimore, MDPHASE238 participantsUniversity of Illinois at Chicago

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NCT05691465Recruiting

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

This phase II trial studies how well lutetium Lu 177 dotatate works in treating patients with prostate cancer with neuroendocrine differentiation that has spread to other places in the body (metastati...

Baltimore, MDPHASE235 participantsNational Cancer Institute (NCI)

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NCT05711615Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first ...

Baltimore, MDPHASE130 participantsNational Cancer Institute (NCI)

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NCT06638294Recruiting

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Traditional clinical trials in patients with breast cancer leptomeningeal disease (LMD) are challenging as patients often have a rapidly progressive course and prognosis is poor, making meeting standa...

Baltimore, MD30 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT06027086Recruiting

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

The purpose of this study is to determine whether the combination of subcutaneous DRP-104 in combination with intravenous Durvalumab is safe and yields a clinically compelling antitumor activity measu...

Baltimore, MDPHASE127 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT06472453Recruiting

Vallomix Socket Preservation Study

This research aims to compare the effectiveness of two bone grafting materials on preserving jawbone integrity after tooth extraction. Following extraction, the jawbone surrounding the removed tooth c...

Baltimore, MDNA24 participantsUniversity of Maryland, Baltimore

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NCT06701812Recruiting

Digoxin Medulloblastoma Study

The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients....

Baltimore, MDPHASE223 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT05671757Recruiting

Daratumumab in Primary Antiphospholipid Syndrome

The purpose of this study is to see if the study medication, daratumumab, is safe to treat individuals with Anti-Phospholipid Syndrome (APS). Three daratumumab dosing cohorts are planned with up to s...

Baltimore, MDPHASE122 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT03266640Recruiting

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovi...

Baltimore, MDPHASE220 participantsNew York Medical College

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NCT05829668Recruiting

Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome

The goals of this clinical trial are to identify factors associated with the development of problem behavior in Cornelia de Lange syndrome (CdLS) and to develop an effective behavioral assessment and ...

Baltimore, MDNA20 participantsHugo W. Moser Research Institute at Kennedy Krieger, Inc.

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NCT05157581Recruiting

Extracorporeal Photopheresis in Sezary Syndrome

The primary endpoint is to determine if ECP induces a decrease in % of tumor cells after treatment. 20 patients with Sezary Syndrome will receive ECP weekly x4, then bi-weekly for 5 months. Each patie...

Baltimore, MD20 participantsOleg E. Akilov, MD, PhD

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NCT06907875Recruiting

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

The goal of this clinical trial is to learn how safe and tolerable EPI-321 is and whether there may be early signs it is working in male or female adult (18 to 75 years) participants with facioscapulo...

Baltimore, MDPHASE112 participantsEpicrispr Biotechnologies, Inc.

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NCT05830721Recruiting

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients

Acute compartment syndrome (ACS) is a surgical emergency that can develop in patients on extracorporeal membrane oxygenation (ECMO). ACS is a type of limb ischemia, which means that the limb, such as ...

Baltimore, MDNA6 participantsJohns Hopkins University

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About Myalgic Encephalomyelitis Clinical Trials in Baltimore

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 45 myalgic encephalomyelitis clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 16,034 participants. Research is being sponsored by Centers for Medicare and Medicaid Services/ Coverage and Analysis Group, Regeneron Pharmaceuticals, Genmab and 30 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in Baltimore — FAQ

Are there myalgic encephalomyelitis clinical trials in Baltimore?

Yes, there are 45 myalgic encephalomyelitis clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 45 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated July 19, 2026 from ClinicalTrials.gov