39 Heart Attack Clinical Trials in Bethesda, MD (2026)

Q: How do I join a clinical trial in Bethesda?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you.

Recruiting Heart Attack Studies in Bethesda

NCT00001373Recruiting

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

This study is designed to explore the genetics and pathophysiology of diseases presenting with intermittent fever, including familial Mediterranean fever, TRAPS, hyper-IgD syndrome, and related diseas...

Bethesda, MD5,000 participantsNational Human Genome Research Institute (NHGRI)

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NCT02974595Recruiting

Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still'S-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)

Background: Some diseases cause chronic inflammation with intermittent flares in the body. These are called autoinflammatory diseases. They can cause fevers, rashes, ulcers, and other problems. Resea...

Bethesda, MD3,200 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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NCT00078078Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations. Affected patients with cblA, cblB and mut class...

Bethesda, MD2,275 participantsNational Human Genome Research Institute (NHGRI)

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NCT00001372Recruiting

Study of Systemic Lupus Erythematosus

This protocol will evaluate patients with systemic lupus erythematosus (SLE) and their relatives to learn more about how the disease develops and changes over time. It will also study genetic factors ...

Bethesda, MD2,000 participantsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

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NCT06676046Recruiting

Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions

Background: The right amount of fats in the blood (cholesterol and triglycerides) are a key part of a healthy organism. Too much or too little of these fats may manifest as diseases (dyslipidemia). T...

Bethesda, MD1,500 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT00001276Recruiting

Diagnosing and Treating Low Blood Sugar Levels

Hypoglycemia is the term used to refer to lower than normal levels of blood sugar. This study will continue to research the causes of hypoglycemia. Patients involved in the study will be admitted to ...

Bethesda, MD1,500 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT01087333Recruiting

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Background: \- Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy v...

Bethesda, MD1,263 participantsNational Cancer Institute (NCI)

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NCT00923507Recruiting

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

Background The development of new technologies now allow scientists to investigate the molecular basis and clinical manifestations of monoclonal B cell lymphocytosis (MBL), chronic lymphocytic leukem...

Bethesda, MD1,000 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT06491615Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

Background: The eyeGENE (Registered Trademark) program is a research resource for inherited eye conditions which includes genotypic and phenotypic data, imaging, and a corresponding biobank of DNA sa...

Bethesda, MD1,000 participantsNational Eye Institute (NEI)

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NCT05012111Recruiting

Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

Background: Bone marrow failure diseases are rare. Much is known about the diseases at the time of diagnosis, but long-term data about the effects of the diseases and treatments are lacking. Research...

Bethesda, MD1,000 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT05254743Recruiting

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

The purpose of Part 1 of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL; participants may or may not have already had treatment...

Bethesda, MDPHASE3737 participantsLoxo Oncology, Inc.

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NCT05131022Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label study designed to evaluate the safety and anti-cancer activity of NX-5948 in patients with advanced B-cell malignancies....

Bethesda, MDPHASE1572 participantsNurix Therapeutics, Inc.

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NCT07154823Recruiting

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient co...

Bethesda, MD550 participantsTempus AI

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NCT04419870Recruiting

Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity

Background: Mitochondrial disease is a rare disorder. It can cause poor growth, developmental delays, muscle weakness, and other symptoms. The disease is usually inherited. It can be present at birth...

Bethesda, MD400 participantsNational Human Genome Research Institute (NHGRI)

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NCT05645107Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

The primary purpose of the study is to evaluate whether biweekly administered XEMBIFY® plus Standard Medical Treatment (SMT) over a one-year period will reduce the rate of major bacterial infections p...

Bethesda, MDPHASE3386 participantsGrifols Therapeutics LLC

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NCT05436418Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Background: Blood cancers (such as leukemias or lymphomas) often do not respond to standard treatments. A transplant of blood stem cells from a healthy donor can help people with these cancers. Somet...

Bethesda, MDPHASE1260 participantsNational Cancer Institute (NCI)

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NCT06846671Recruiting

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

The purpose of this study is to investigate the efficacy and safety of BGB-16673 compared with investigator's choice (idelalisib plus rituximab \[for CLL only\] or bendamustine plus rituximab or venet...

Bethesda, MDPHASE3250 participantsBeiGene

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NCT05047354Recruiting

Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabolism

Background: Smith-Lemli-Opitz Syndrome (SLOS) is a genetic disorder. It can cause birth defects and developmental delays. There is no cure for SLOS or other inherited diseases related to cholesterol ...

Bethesda, MD250 participantsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

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NCT06588478Recruiting

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (S...

Bethesda, MDPHASE2249 participantsLoxo Oncology, Inc.

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NCT04830137Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-2127 in patients with advanced B-cell malignancies....

Bethesda, MDPHASE1248 participantsNurix Therapeutics, Inc.

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NCT06093672Recruiting

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

The goal of this clinical trial is to compare the efficacy and safety of givinostat to hydroxyurea in Jak2V617F-positive high risk polycythemia vera patients....

Bethesda, MDPHASE3220 participantsItalfarmaco

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NCT06897930Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study of AZD0120, a CD19/BCMA dual CAR T cell therapy, to evaluate the safety, tolerability, and efficacy in adult participants wit...

Bethesda, MDPHASE1150 participantsAstraZeneca

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NCT05724121Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Background: Bruton s tyrosine kinase inhibitors (BTKi) are used to treat a form of leukemia. But taking BTKi can also increase a person s risk of developing an abnormal heart rhythm. This can cause s...

Bethesda, MD135 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT06364423Recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

Background: Chronic lymphocytic leukemia (CLL),small lymphocytic lymphoma (SLL) and B-cell acute lymphoblastic leukemia or lymphoma (ALL) are blood cancers that affect certain white blood cells. Adva...

Bethesda, MDPHASE1132 participantsNational Cancer Institute (NCI)

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NCT01174108Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

Background: * Stem cell transplants from related donors (allogenic stem cell transplants) can be used to treat individuals with certain kinds of severe blood diseases or cancers, such as severe anemi...

Bethesda, MDPHASE2120 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT05835310Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE...

Bethesda, MDPHASE3100 participantsAstraZeneca

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NCT05567198Recruiting

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

Background: Systemic lupus erythematosus (SLE) is a disease that affects females nine times more often than males. People with SLE are often treated with cyclophosphamide (CYC). But CYC can damage a ...

Bethesda, MD100 participantsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

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NCT04304820Recruiting

Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

Background: Severe aplastic anemia (SAA) is a rare and serious blood disorder. It causes the immune system to turn against bone marrow cells. Standard treatment for SSA is a combination of 3 drugs (C...

Bethesda, MDPHASE280 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT06032923Recruiting

Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus

Study Description: Systemic lupus erythematosus (SLE) occurs predominantly in women and is driven by type I interferon dysregulation and neutrophil hyperresponsiveness. Neutrophils in females have re...

Bethesda, MDPHASE178 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT07267819Recruiting

Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents

This cohort study aims to compare the efficacy of Xeomin injections for migraine management in patients with a history of Traumatic Brain Injury (TBI) versus those with a history of Anomalous Health I...

Bethesda, MD60 participantsUniformed Services University of the Health Sciences

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NCT05104736Recruiting

PT-112 in Subjects With Thymoma and Thymic Carcinoma

Background: There are no approved drugs to treat recurrent thymoma and thymic carcinoma. New therapies are needed for people with these cancers. Researchers want to see if the drug PT-112 can help. P...

Bethesda, MDPHASE253 participantsNational Cancer Institute (NCI)

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NCT05440422Recruiting

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Background: People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. This can increase the risk of heart attacks or stroke. No medications have b...

Bethesda, MDPHASE245 participantsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

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NCT04322383Recruiting

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

Background: Most people with hairy cell leukemia have a BRAF gene mutation. They can be treated with BRAF inhibitors, drugs that target this mutation. For people who do not have this mutation, BRAF i...

Bethesda, MDPHASE240 participantsNational Cancer Institute (NCI)

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NCT03173937Recruiting

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to...

Bethesda, MDPHASE137 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT07649317Recruiting

Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol Secretion

Background: Cortisol is a hormone in the blood. Cortisol levels normally go down at night and up in the morning. Mild autonomous cortisol secretion (MACS) is a disease in which the body makes too muc...

Bethesda, MDPHASE136 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT07428707Recruiting

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

Background: Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are blood cancers that affect certain white blood cells. Advanced forms of these diseases are difficult to treat. P...

Bethesda, MDEARLY_PHASE130 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT07566494Recruiting

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

Background: Sickle cell disease (SCD) is an inherited blood disorder. The disease affects the ability of red blood cells to carry oxygen. Research has shown that curcumin, a natural compound found in...

Bethesda, MDPHASE125 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Bethesda, MDPHASE120 participantsAdaptimmune

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NCT06744283Recruiting

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

Background: Fanconi anemia (FA) is a rare, inherited cancer syndrome. FA causes a range of physical issues. Children with FA may have abnormal features; these may include a small head and eyes and is...

Bethesda, MD20 participantsNational Cancer Institute (NCI)

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About Heart Attack Clinical Trials in Bethesda

A heart attack (myocardial infarction) occurs when blood flow to part of the heart muscle is blocked, usually by a blood clot. It is a medical emergency requiring immediate treatment. Long-term management includes medications, lifestyle changes, and cardiac rehabilitation.

There are currently 39 heart attack clinical trials recruiting participants in Bethesda, MD. These studies are seeking a combined 25,121 participants. Research is being sponsored by National Human Genome Research Institute (NHGRI), National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and 14 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Attack Clinical Trials in Bethesda — FAQ

Are there heart attack clinical trials in Bethesda?

Yes, there are 39 heart attack clinical trials currently recruiting in Bethesda, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Bethesda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you about next steps.

Are clinical trials in Bethesda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Bethesda studies also compensate for your time and travel.

What heart attack treatments are being tested?

The 39 active trials in Bethesda are testing new therapies including novel drugs, biologics, and treatment approaches for heart attack.

Data updated July 17, 2026 from ClinicalTrials.gov