15 Prostate Cancer Clinical Trials in Bethesda, MD (2026)

Q: How do I join a clinical trial in Bethesda?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you.

Recruiting Prostate Cancer Studies in Bethesda

NCT02594202Recruiting

Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

Background: Prostate cancer is the most common noncutaneous cancer among men in the U.S. Researchers want to study blood, tissue, and fluid samples of people with prostate cancer. This will help them...

Bethesda, MD3,000 participantsNational Cancer Institute (NCI)

View Study Details

NCT04706663Recruiting

Precision-Based Genomics in Prostate Cancer

Background: Prostate cancer is the most common cancer and the second leading cause of death in males in the United States. Researchers want to find additional gene mutations that may increase a man s...

Bethesda, MD2,000 participantsNational Cancer Institute (NCI)

View Study Details

NCT00034216Recruiting

Collection of Blood From Patients With Cancer

This study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy. Patients 18 years of age and ol...

Bethesda, MD1,750 participantsNational Cancer Institute (NCI)

View Study Details

NCT06398639Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

The goal of this clinical trial is to evaluate a screening method to detect clinically relevant prostate cancer. This clinical trial is using genetic data to determine a man's risk of cancer, together...

Bethesda, MDNA1,500 participantsAdam S. Kibel, MD

View Study Details

NCT01441089Recruiting

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Background: \- Some genes may be associated with a greater chance of side effects during cancer treatment. These genes may also make certain treatments less effective. Researchers want to collect blo...

Bethesda, MD1,100 participantsNational Cancer Institute (NCI)

View Study Details

NCT06804785Recruiting

Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer (HIT-PIRADS)

The purpose of this study is to develop a new way to diagnose prostate cancer through the use of artificial intelligence. The goal is for this new method to reduce delays in diagnoses and to avoid inv...

Bethesda, MD800 participantsNorthwestern University

View Study Details

NCT00451022Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

This study aims to provide long-term follow-up care of patients previously enrolled in a vaccine study that involved poxviral vectors. Vectors are sequences of genetic material that can be used to int...

Bethesda, MD750 participantsNational Cancer Institute (NCI)

View Study Details

NCT04692675Recruiting

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

Background: Active surveillance (AS) is a standard approach to treat low and intermediate risk prostate cancer. For AS, disease progression is monitored. AS uses biopsies, prostate specific antigen (...

Bethesda, MDNA508 participantsNational Cancer Institute (NCI)

View Study Details

NCT05588128Recruiting

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

Background: Prostate cancer is the second leading cause of cancer-related death in American men. The disease recurs in up to 50,000 men each year after their early-stage disease was treated; however,...

Bethesda, MD350 participantsNational Cancer Institute (NCI)

View Study Details

NCT04729114Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

Medicines that reduce the amount of testosterone in the body are commonly used to treat prostate cancer. PRL-02 depot is a potential treatment for men with advanced prostate cancer. It is given by an ...

Bethesda, MDPHASE1174 participantsAstellas Pharma Global Development, Inc.

View Study Details

NCT06991556Recruiting

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

This Phase II study aims to evaluate efficacy and safety of the combination of JSB462 (also known as luxdegalutamide) at 100 mg and 300 mg once a day (QD) doses + abiraterone compared with an androgen...

Bethesda, MDPHASE2150 participantsNovartis Pharmaceuticals

View Study Details

NCT05155046Recruiting

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

Background: Identifying medium- and high-risk prostate cancer early may allow for treatments to work. But identification can be hard. Researchers want to see if a radiotracer used during PET scans ca...

Bethesda, MDPHASE2130 participantsNational Cancer Institute (NCI)

View Study Details

NCT06096870Recruiting

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Background: Prostate cancer may return after treatment in 30,000 to 50,000 people each year. There is no clear best way to treat these people. Better treatments are needed. Objective: To test a stu...

Bethesda, MDPHASE265 participantsNational Cancer Institute (NCI)

View Study Details

NCT06257693Recruiting

Enzalutamide Implants (Enolen) in Patients With Prostate Cancer

The study is to assess whether the Enolen is safe and delivers anti-androgen medication locally in patients that are planning for radical prostatectomy....

Bethesda, MDPHASE156 participantsAlessa Therapeutics Inc.

View Study Details

NCT04808427Recruiting

Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer

Background: The ability to treat early prostate cancer is still limited. Thermal ablation methods are being tested for focal prostate cancer therapy. Researchers want to improve on these methods. Ob...

Bethesda, MDNA21 participantsNational Cancer Institute (NCI)

View Study Details

About Prostate Cancer Clinical Trials in Bethesda

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 15 prostate cancer clinical trials recruiting participants in Bethesda, MD. These studies are seeking a combined 12,354 participants. Research is being sponsored by National Cancer Institute (NCI), Adam S. Kibel, MD, Northwestern University and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Bethesda — FAQ

Are there prostate cancer clinical trials in Bethesda?

Yes, there are 15 prostate cancer clinical trials currently recruiting in Bethesda, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Bethesda?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Bethesda research site will contact you about next steps.

Are clinical trials in Bethesda free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Bethesda studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 15 active trials in Bethesda are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated July 17, 2026 from ClinicalTrials.gov