Birmingham, ALABAMA4 Active Studies

B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Birmingham, ALABAMA

Find 4 actively recruiting b-cell acute lymphoblastic leukemia clinical trials in Birmingham, ALABAMA. Connect with local research sites and explore new treatment options.

4
Active Trials
3
Sponsors
5,775
Enrolling

Recruiting B-Cell Acute Lymphoblastic Leukemia Studies in Birmingham

RecruitingBirmingham, ALABAMANCT03959085

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial al...

4,997 participants
Children's Oncology Group
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RecruitingBirmingham, ALABAMANCT04546399

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come ...

461 participants
National Cancer Institute (NCI)
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RecruitingBirmingham, ALABAMANCT06124157

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

This pilot trial assesses the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (Ph+) or ABL-cl...

222 participants
National Cancer Institute (NCI)
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RecruitingBirmingham, ALABAMANCT03509961

The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal resi...

95 participants
Pediatric Transplantation & Cellular Therapy Consortium
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About B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Birmingham

B-cell acute lymphoblastic leukemia (B-ALL) is a fast-growing cancer of the B-type lymphocyte white blood cells. It is the most common childhood cancer but can also occur in adults. Treatment includes chemotherapy, targeted therapy, and CAR-T cell therapy.

There are currently 4 b-cell acute lymphoblastic leukemia clinical trials recruiting participants in Birmingham, ALABAMA. These studies are seeking a combined 5,775 participants. Research is being sponsored by Children's Oncology Group, National Cancer Institute (NCI), Pediatric Transplantation & Cellular Therapy Consortium. Clinical trial participation is free and participants receive study-related medical care at no cost.

B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Birmingham — FAQ

Are there b-cell acute lymphoblastic leukemia clinical trials in Birmingham?

Yes, there are 4 b-cell acute lymphoblastic leukemia clinical trials currently recruiting in Birmingham, ALABAMA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What b-cell acute lymphoblastic leukemia treatments are being tested?

The 4 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for b-cell acute lymphoblastic leukemia.

Data updated March 2, 2026 from ClinicalTrials.gov