Birmingham, ALABAMA5 Active Studies

Sarcoma Clinical Trials in Birmingham, ALABAMA

Find 5 actively recruiting sarcoma clinical trials in Birmingham, ALABAMA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
1,655
Enrolling

Recruiting Sarcoma Studies in Birmingham

RecruitingBirmingham, ALABAMANCT05691478

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

This phase II/III trial tests the safety, side effects, and best dose of the drug cabozantinib in combination with standard chemotherapy, and to compare the effect of adding cabozantinib to standard c...

1,122 participants
National Cancer Institute (NCI)
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RecruitingBirmingham, ALABAMANCT05235165

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has ...

250 participants
Children's Oncology Group
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RecruitingBirmingham, ALABAMANCT05304585

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phase III trial aims to maintain excellent outcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) whi...

205 participants
Children's Oncology Group
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RecruitingBirmingham, ALABAMANCT05634369

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docet...

50 participants
Nationwide Children's Hospital
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RecruitingBirmingham, ALABAMANCT04388839

Evolutionary Therapy for Rhabdomyosarcoma

This clinical trial will evaluate 4 different strategies of chemotherapy schedules in newly diagnosed participants with metastatic Fusion Positive (alveolar) Rhabdomyosarcoma. The participant and thei...

28 participants
H. Lee Moffitt Cancer Center and Research Institute
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About Sarcoma Clinical Trials in Birmingham

Sarcomas are rare cancers that arise in bone and soft tissues including muscle, fat, blood vessels, and connective tissue. There are more than 70 subtypes of sarcoma. Treatment usually involves surgery combined with radiation and/or chemotherapy.

There are currently 5 sarcoma clinical trials recruiting participants in Birmingham, ALABAMA. These studies are seeking a combined 1,655 participants. Research is being sponsored by National Cancer Institute (NCI), Children's Oncology Group, Nationwide Children's Hospital and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Sarcoma Clinical Trials in Birmingham — FAQ

Are there sarcoma clinical trials in Birmingham?

Yes, there are 5 sarcoma clinical trials currently recruiting in Birmingham, ALABAMA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What sarcoma treatments are being tested?

The 5 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for sarcoma.

Data updated March 2, 2026 from ClinicalTrials.gov