Birmingham, MI14 Active Studies

Advanced Solid Tumors Clinical Trials in Birmingham, MI

Find 14 actively recruiting advanced solid tumors clinical trials in Birmingham, MI. Connect with local research sites and explore new treatment options.

14
Active Trials
10
Sponsors
9,365
Enrolling

Recruiting Advanced Solid Tumors Studies in Birmingham

RecruitingBirmingham, MINCT02693535

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

The purpose of the study is to learn from the real world practice of prescribing targeted therapies to patients with advanced cancer whose tumor harbors a genomic variant known to be a drug target or ...

4,200 participants
American Society of Clinical Oncology
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RecruitingBirmingham, MINCT05564377

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nea...

2,900 participants
National Cancer Institute (NCI)
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RecruitingBirmingham, MINCT04657068

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

This clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors. The main goals of this study are to: * Find the recommended dose of ART0380 that can ...

597 participants
Artios Pharma Ltd
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RecruitingBirmingham, MINCT06265727

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

The goal of this clinical trial is to define a safe and effective dose of CRB-701 for participants with solid tumors that are expressing a protein called nectin-4. The main questions it aims to answe...

348 participants
Corbus Pharmaceuticals Inc.
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RecruitingBirmingham, MINCT04939610

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Fibroblast activation protein (FAP) is a cell surface protein that is highly expressed on the surface of cancer-associated fibroblasts (CAFs) present in the tumor microenvironment of most epithelial c...

222 participants
Novartis Pharmaceuticals
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RecruitingBirmingham, MINCT06635785

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

BIPAVE-001 is a Phase 1-2 study for evaluating the safety, pharmacokinetics (PK), and efficacy of AI-081 in solid tumors....

204 participants
OncoC4, Inc.
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RecruitingBirmingham, MINCT06818643

A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

Researchers are looking for new ways to treat people with certain advanced solid tumors. Advanced means the cancer has spread to other parts of the body and cannot be removed with surgery. Solid tumor...

180 participants
Merck Sharp & Dohme LLC
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RecruitingBirmingham, MINCT06603844

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

The purpose of this study is to determine the safety, blood concentrations and treatment effect of CRB-601 in combination with immunotherapy in patients who have advanced solid tumors (cancer) and hav...

156 participants
Corbus Pharmaceuticals Inc.
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RecruitingBirmingham, MINCT04851119

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or does not respond to tr...

147 participants
Children's Oncology Group
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RecruitingBirmingham, MINCT06760819

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Researchers are looking for a better way to treat people who have solid tumors with HER2-activating mutations. Before a treatment can be approved for people to take, researchers do clinical trials to ...

111 participants
Bayer
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RecruitingBirmingham, MINCT05135975

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

This study will expand the types of pediatric cancers being evaluated for response to cabozantinib. The current COG study is restricted to Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, Wilms tumor, a...

86 participants
Nationwide Children's Hospital
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RecruitingBirmingham, MINCT06620302

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

This phase I/II trial tests the safety, side effects and best dose of DT2216 in combination with irinotecan and how well it works in treating children, adolescents and young adults with solid tumors a...

81 participants
Children's Oncology Group
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RecruitingBirmingham, MINCT06126276

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positive solid tumors. Neratinib and palbocicli...

70 participants
National Cancer Institute (NCI)
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RecruitingBirmingham, MINCT04870944

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

This phase I/II trial evaluates the best dose, side effects and possible benefit of CBL0137 in treating patients with solid tumors, including central nervous system (CNS) tumors or lymphoma that has c...

63 participants
Children's Oncology Group
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About Advanced Solid Tumors Clinical Trials in Birmingham

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 14 advanced solid tumors clinical trials recruiting participants in Birmingham, MI. These studies are seeking a combined 9,365 participants. Research is being sponsored by American Society of Clinical Oncology, National Cancer Institute (NCI), Artios Pharma Ltd and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Birmingham — FAQ

Are there advanced solid tumors clinical trials in Birmingham?

Yes, there are 14 advanced solid tumors clinical trials currently recruiting in Birmingham, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 14 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated March 2, 2026 from ClinicalTrials.gov