Boca Raton, FL26 Active Studies

Ankylosing Spondylitis Clinical Trials in Boca Raton, FL

Find 26 actively recruiting ankylosing spondylitis clinical trials in Boca Raton, FL. Connect with local research sites and explore new treatment options.

26
Active Trials
20
Sponsors
15,710
Enrolling

Recruiting Ankylosing Spondylitis Studies in Boca Raton

RecruitingBoca Raton, FLNCT07157774

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart a...

10,450 participants
Eli Lilly and Company
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RecruitingBoca Raton, FLNCT04638647

Secukinumab Open Label Roll-over Extension Protocol

The purpose of this study is to assess long term safety in participants who have completed a Novartis trial with secukinumab, have been judged by the investigator to benefit from continued treatment w...

715 participants
Novartis Pharmaceuticals
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RecruitingBoca Raton, FLNCT06875973

Pelacarsen Roll-over Extension Program

This non-randomized, rollover extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed either of the double-blind parent studies (CTQJ230A1...

600 participants
Novartis Pharmaceuticals
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RecruitingBoca Raton, FLNCT06544616

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

The purpose of this study is to assess the effect of JNJ-64042056 on cognitive decline, as measured by Preclinical Alzheimer's disease Cognitive Composite 5 (PACC-5) compared with placebo....

498 participants
Janssen Pharmaceutica N.V., Belgium
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RecruitingBoca Raton, FLNCT06813911

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

The purpose of the study CTQJ230A12304, is to evaluate the efficacy, safety, and tolerability of pelacarsen (TQJ230) compared to placebo in participants with ASCVD who have elevated lipoprotein(a) (Lp...

340 participants
Novartis Pharmaceuticals
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RecruitingBoca Raton, FLNCT06553027

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Participants will be randomized to receive once-daily o...

330 participants
Cerevance
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RecruitingBoca Raton, FLNCT06538116

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementi...

300 participants
Eli Lilly and Company
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RecruitingBoca Raton, FLNCT06887192

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

ML-007C-MA-221 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ML-007C-MA in male and female participants aged 55 to 90 years with hallucination...

300 participants
MapLight Therapeutics
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RecruitingBoca Raton, FLNCT06463587

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

The purpose of this clinical study is to determine the efficacy and safety of a new oral cladribine formulation in participants with Generalized Myasthenia Gravis (gMG) in comparison to placebo. It wi...

264 participants
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
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RecruitingBoca Raton, FLNCT06765668

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

The primary purpose of this study is to evaluate efficacy and safety of CREXONT under real world conditions in participants with Parkinson disease (PD)....

220 participants
Impax Laboratories, LLC
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RecruitingBoca Raton, FLNCT06456580

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (RemeMG)

The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of generalized myasthenia gravis....

180 participants
RemeGen Co., Ltd.
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RecruitingBoca Raton, FLNCT06744920

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

A study to evaluate the efficacy, safety and tolerability of Remibrutinib versus placebo in adult patients with Generalized Myasthenia Gravis who are on stable, standard-of-care (SOC) treatment....

180 participants
Novartis Pharmaceuticals
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RecruitingBoca Raton, FLNCT04123795

A Study to Evaluate the Pharmacokinetics, Safety, and Effectiveness of Certolizumab Pegol in Children With Moderate to Severe Chronic Plaque Psoriasis

The purpose of the study is to evaluate the pharmacokinetic (PK) of certolizumab pegol (CZP) in study participants aged 6 to 17 years with moderate to severe chronic plaque psoriasis (PSO) in order to...

150 participants
UCB Biopharma SRL
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RecruitingBoca Raton, FLNCT06680830

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the ...

150 participants
Neuron23 Inc.
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RecruitingBoca Raton, FLNCT06517758

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.

The study is a randomized, double-blind, placebo-controlled, multicenter, Phase III study, to evaluate efficacy, safety and tolerability of iptacopan in patients with AChR+ gMG who are on stable SOC t...

146 participants
Novartis Pharmaceuticals
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RecruitingBoca Raton, FLNCT05766813

Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Soc...

132 participants
Intra-Cellular Therapies, Inc.
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RecruitingBoca Raton, FLNCT06558279

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

The purpose of this study is to evaluate the efficacy and safety of efgartigimod PH20 SC given by a pre-filled syringe in adult patients with ocular myasthenia gravis. The study consists of a part A (...

124 participants
argenx
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RecruitingBoca Raton, FLNCT06440525

A Study of RSLV-132 in Females With Sjögren's Disease

The goal of this clinical study is to learn if RSLV-132 improves the symptoms of SS in adults. It will also learn about the safety of RSLV-132. The main questions it aims to answer are: * Does RSLV-1...

106 participants
Resolve Therapeutics
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RecruitingBoca Raton, FLNCT06944522

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

Study BRT-DA01-301 is a Phase 3 multicenter, randomized, sham surgery-controlled, double-blind study to assess efficacy and safety of bemdaneprocel in approximately 102 adults with Parkinson's Disease...

102 participants
BlueRock Therapeutics
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RecruitingBoca Raton, FLNCT06285643

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered to the putamen in subjects with moderate Parkinson'...

87 participants
AskBio Inc
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RecruitingBoca Raton, FLNCT06414954

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, a...

84 participants
NMD Pharma A/S
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RecruitingBoca Raton, FLNCT06344052

To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma

The goal of this clinical trial is to evaluate the efficacy of using SP-002 in participants with locally advanced Basal cell carcinoma. The main question it aims to answer is what the objective respon...

80 participants
Stamford Pharmaceuticals, Inc.
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RecruitingBoca Raton, FLNCT06773962

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

The primary objectives of this study are to assess the efficacy of TB006 in improving motor function and to assess the safety of TB006 in participants with Parkinson's Disease (PD)....

62 participants
TrueBinding, Inc.
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RecruitingBoca Raton, FLNCT06602193

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

This Phase 2a, multicenter, randomized, 12-week double-blind, placebo-controlled, parallel-group study, followed by an OLE, is designed to evaluate the safety, tolerability, and pharmacodynamic effect...

50 participants
Denali Therapeutics Inc.
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RecruitingBoca Raton, FLNCT06909214

A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)

The main purpose of this study is to measure how well adults with new-onset gMG (which means they've had generalized disease signs and/or symptoms for less than 1 year) respond to treatment with efgar...

30 participants
argenx
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RecruitingBoca Raton, FLNCT06822517

A Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease

This trial is a randomized, double-blind, placebo-controlled Phase 1b study evaluating the safety/tolerability, PK, and pharmacodynamics of VENT 02, administered orally at 1 dose level twice daily (BI...

30 participants
Ventus Therapeutics U.S., Inc.
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About Ankylosing Spondylitis Clinical Trials in Boca Raton

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 26 ankylosing spondylitis clinical trials recruiting participants in Boca Raton, FL. These studies are seeking a combined 15,710 participants. Research is being sponsored by Eli Lilly and Company, Novartis Pharmaceuticals, Janssen Pharmaceutica N.V., Belgium and 17 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Boca Raton — FAQ

Are there ankylosing spondylitis clinical trials in Boca Raton?

Yes, there are 26 ankylosing spondylitis clinical trials currently recruiting in Boca Raton, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boca Raton?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boca Raton research site will contact you about next steps.

Are clinical trials in Boca Raton free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boca Raton studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 26 active trials in Boca Raton are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov