Boston, MA5 Active Studies

Bladder Cancer Clinical Trials in Boston, MA

Find 5 actively recruiting bladder cancer clinical trials in Boston, MA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
568
Enrolling

Recruiting Bladder Cancer Studies in Boston

RecruitingBoston, MANCT05544552

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of TYRA-300 in cancers with FGFR3 activating gene alterations, including lo...

310 participants
Tyra Biosciences, Inc
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RecruitingBoston, MANCT06483334

A Study of Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

This study is a substudy being conducted under one pembrolizumab umbrella master study KEYMAKER-U04. The substudy will consist of 2 parts. Part 1 will evaluate the safety and preliminary efficacy of s...

98 participants
Merck Sharp & Dohme LLC
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RecruitingBoston, MANCT05710848

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

This is a first-in-human (FIH), Phase 1/2a, multi center, open-label, single treatment, dose escalation and expansion study designed to determine the safety and tolerability of STM-416 in patients wit...

75 participants
SURGE Therapeutics
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RecruitingBoston, MANCT03317158

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Upon successful screening and registration, enrollment to durvalumab monotherapy (cohort 1) will begin. If DLT criteria outlined in the protocol are exceeded with durvalumab monotherapy (cohort 1), th...

55 participants
Noah Hahn, M.D.
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RecruitingBoston, MANCT04701918

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

This research study is examining the effectiveness of pembrolizumab plus cryoablation or aveluma plus cryoablation on people with urothelial carcinoma, including bladder cancer, that has spread....

30 participants
Massachusetts General Hospital
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About Bladder Cancer Clinical Trials in Boston

Bladder cancer occurs in the tissues of the bladder and is one of the most common cancers. It has a high recurrence rate, requiring ongoing monitoring. Treatments include surgery, intravesical therapy, chemotherapy, and immunotherapy.

There are currently 5 bladder cancer clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 568 participants. Research is being sponsored by Tyra Biosciences, Inc, Merck Sharp & Dohme LLC, SURGE Therapeutics and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Bladder Cancer Clinical Trials in Boston — FAQ

Are there bladder cancer clinical trials in Boston?

Yes, there are 5 bladder cancer clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What bladder cancer treatments are being tested?

The 5 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for bladder cancer.

Data updated March 2, 2026 from ClinicalTrials.gov