14 Pediatric Cancer Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Pediatric Cancer Studies in Boston

NCT04511806Recruiting

Childhood Cancer Predisposition Study (CCPS)

The Childhood Cancer Predisposition Study (CCPS) is a multi-center, longitudinal, observational study that will collect clinical and biological data and specimens from children with a cancer predispos...

Boston, MA1,050 participantsEmory University

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NCT01587300Recruiting

Neuroblastoma Biology Study

Medical scientists want to find better ways to treat neuroblastoma and to find ways to prevent the tumor from growing back. To do this, they need more information about the characteristics of neurobla...

Boston, MA1,000 participantsNew Approaches to Neuroblastoma Therapy Consortium

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NCT06786104Recruiting

Video Inspired Discussions About Ethical Outcomes in Pediatrics

The goal of this clinical trial is to learn if the VIDEO-PEDS intervention works to improve Goals of Care communication between clinicians and parents of children with cancer. The main questions it a...

Boston, MA567 participantsMassachusetts General Hospital

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NCT06055296Recruiting

Multisite Implementation of COMPRENDO

COMPRENDO (ChildhOod Malignancy Peer Research NavigatiOn) is a multi-site randomized clinical trial (RCT) that uses a Hybrid Type 1 design, to test the effects of a clinical intervention on patient-le...

Boston, MA450 participantsUniversity of California, San Diego

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NCT02332668Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood cancers) that are any of these: * Advanced, which means cance...

Boston, MA370 participantsMerck Sharp & Dohme LLC

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NCT06831552Recruiting

Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

The goal of this study is to test if the addition of a novel income-poverty targeted supportive care intervention (Pediatric Resource Intervention to Support Equity \[Pediatric RISE\]) to usual suppor...

Boston, MA84 participantsDana-Farber Cancer Institute

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NCT06450041Recruiting

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

This is a phase II study looking at patient response to treatment with the combination dinutuximab, temozolomide, irinotecan, and GM-CSF....

Boston, MA62 participantsNew Approaches to Neuroblastoma Therapy Consortium

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NCT05985161Recruiting

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPNST, or another solid tumor that makes a h...

Boston, MA45 participantsMemorial Sloan Kettering Cancer Center

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NCT06803875Recruiting

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

This Phase 1/2 trial aims to determine the safety and feasibility of administration of autologous chimeric antigen receptor (CAR) T cells targeting the human Anaplastic Lymphoma Kinase (ALK) receptor ...

Boston, MA42 participantsRoberto Chiarle

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NCT06283251Recruiting

PediRISE Feasibility

The goal of this research study is to learn whether investigators can successfully give the PediRISE program to families-in other words, whether most families are interested in participating in a stud...

Boston, MA40 participantsDana-Farber Cancer Institute

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NCT02112617Recruiting

Phase II Study of Proton Radiation Therapy for Neuroblastoma

This research study is evaluating a therapy called proton beam radiation therapy (PBRT) as a possible treatment for neuroblastoma. Neuroblastoma most commonly occurs in and around the adrenal glands,...

Boston, MA30 participantsMassachusetts General Hospital

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NCT04796012Recruiting

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

This trial is a multi-center, non-randomized, open-label Phase I/II study evaluating the feasibility and efficacy of vincristine, irinotecan, temozolomide, and atezolizumab in children with relapsed/r...

Boston, MA23 participantsUniversity of Texas Southwestern Medical Center

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NCT07027748Recruiting

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

This research is being done to investigate a treatment regimen of Irinotecan, Temozolomide, and Sargramostin, and an immunotherapy called Naxitamab and whether giving Naxitamab more slowly reduces the...

Boston, MA18 participantsSteven DuBois, MD

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NCT06609473Recruiting

Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors

The goal of the Cardiovascular Health Equity Through Food (CHEF) program is to make it easier for participants and families to cook and eat healthy foods during and following childhood cancer treatmen...

Boston, MA17 participantsDana-Farber Cancer Institute

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About Pediatric Cancer Clinical Trials in Boston

Pediatric cancers include a wide range of cancers occurring in children and adolescents, with leukemia, brain tumors, and lymphoma being most common. Overall cure rates have improved dramatically to about 80%. Treatment includes chemotherapy, surgery, radiation, and newer immunotherapies.

There are currently 14 pediatric cancer clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 3,798 participants. Research is being sponsored by Emory University, New Approaches to Neuroblastoma Therapy Consortium, Massachusetts General Hospital and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pediatric Cancer Clinical Trials in Boston — FAQ

Are there pediatric cancer clinical trials in Boston?

Yes, there are 14 pediatric cancer clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What pediatric cancer treatments are being tested?

The 14 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for pediatric cancer.

Data updated July 13, 2026 from ClinicalTrials.gov