12 Retinitis Pigmentosa Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Retinitis Pigmentosa Studies in Boston

NCT01561157Recruiting

Longitudinal Study of the Porphyrias

The objective of this protocol is to conduct a longitudinal multidisciplinary investigation of the human porphyrias including the natural history, morbidity, pregnancy outcomes, and mortality in peopl...

Boston, MA1,500 participantsThe American Porphyrias Expert Collaborative

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NCT05005975Recruiting

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

To evaluate the long-term safety and tolerability of oral dersimelagon....

Boston, MAPHASE3301 participantsMitsubishi Tanabe Pharma America Inc.

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NCT06944145Recruiting

New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia

SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH). SRD5A2 is absent in 30% of normal adult me...

Boston, MAPHASE2242 participantsBeth Israel Deaconess Medical Center

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NCT07159841Recruiting

A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of atumelnant treatment in pediatric participants with classic congenital adrenal hyperp...

Boston, MAPHASE2153 participantsCrinetics Pharmaceuticals Inc.

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NCT04883905Recruiting

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effec...

Boston, MA150 participantsAlnylam Pharmaceuticals

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NCT06948318Recruiting

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Primary immune thrombocytopenia (ITP) is a condition where the immune system mistakenly destroys platelets, which are cells that help stop bleeding. This leads to a lower number of platelets, making i...

Boston, MAPHASE3150 participantsTakeda

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NCT04288427Recruiting

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which...

Boston, MANA120 participantsBeth Israel Deaconess Medical Center

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NCT07567131Recruiting

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

The purpose of this study is to collect information about the effects of EPP/XLP in adults and adolescents. This is an observational study in which participants will not receive any treatment. Study d...

Boston, MA50 participantsPortal Therapeutics, Inc.

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NCT07148089Recruiting

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

This is a Phase 1b, Multicenter, Open-Label, Dose Finding Study to Investigate the Safety and Tolerability of a Single Intravenous Dose of SGT-501 in participants with catecholaminergic polymorphic ve...

Boston, MAPHASE118 participantsSolid Biosciences Inc.

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NCT02851758Recruiting

Transplantation of Autologously Derived Mitochondria Following Ischemia

The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring extracorporea...

Boston, MANA16 participantsBoston Children's Hospital

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NCT06891885Recruiting

A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

The Goal of this study is to evaluate the safety, tolerability, and clinical responses following single dose of DSP-3077. Study enrolls both male and female patients in 3 cohorts with each cohort defi...

Boston, MAPHASE112 participantsSumitomo Pharma America, Inc.

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NCT07476183Recruiting

Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia

Brief summary The goal of this clinical trial is to learn if APR-2020 is safe and can help treat Diamond-Blackfan Anemia (DBA) in adolescents and children. The main questions it aims to answer are: ...

Boston, MAPHASE14 participantsApriligen, Inc.

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About Retinitis Pigmentosa Clinical Trials in Boston

Retinitis pigmentosa (RP) is a group of inherited retinal diseases that cause progressive loss of photoreceptor cells in the retina, leading to vision loss. It typically begins with night blindness and progresses to tunnel vision. Gene therapy and retinal implants are areas of active research.

There are currently 12 retinitis pigmentosa clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 2,716 participants. Research is being sponsored by The American Porphyrias Expert Collaborative, Mitsubishi Tanabe Pharma America Inc., Beth Israel Deaconess Medical Center and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Retinitis Pigmentosa Clinical Trials in Boston — FAQ

Are there retinitis pigmentosa clinical trials in Boston?

Yes, there are 12 retinitis pigmentosa clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What retinitis pigmentosa treatments are being tested?

The 12 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for retinitis pigmentosa.

Data updated July 17, 2026 from ClinicalTrials.gov