Recruiting Systemic Mastocytosis Studies in Boston
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
This is a randomized, double-blind, placebo-controlled, Phase 2/3 study comparing the efficacy and safety of elenestinib (BLU-263) + symptom directed therapy (SDT) with placebo + SDT in participants w...
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
This is an open-label, two-part Phase 2 study investigating CGT9486 for the treatment of patients with Advanced Systemic Mastocytosis (AdvSM), including patients with Aggressive SM (ASM), SM with Asso...
About Systemic Mastocytosis Clinical Trials in Boston
Systemic mastocytosis is a rare condition caused by accumulation of abnormal mast cells in the bone marrow, skin, liver, spleen, and GI tract. It can cause allergic reactions, bone pain, and organ damage. Treatment includes targeted therapies, antihistamines, and mast cell stabilizers.
There are currently 2 systemic mastocytosis clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 674 participants. Research is being sponsored by Blueprint Medicines Corporation, Cogent Biosciences, Inc.. Clinical trial participation is free and participants receive study-related medical care at no cost.
Systemic Mastocytosis Clinical Trials in Boston — FAQ
Are there systemic mastocytosis clinical trials in Boston?
Yes, there are 2 systemic mastocytosis clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Boston?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.
Are clinical trials in Boston free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.
What systemic mastocytosis treatments are being tested?
The 2 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for systemic mastocytosis.
Data updated March 2, 2026 from ClinicalTrials.gov