Boston, MASSACHUSETTS4 Active Studies

Cardiomyopathy Clinical Trials in Boston, MASSACHUSETTS

Find 4 actively recruiting cardiomyopathy clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

4
Active Trials
4
Sponsors
1,855
Enrolling

Recruiting Cardiomyopathy Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT07052903

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

The purpose of this study is to: * Evaluate the efficacy of nucresiran compared to placebo on reducing all-cause mortality and cardiovascular (CV) events * Evaluate the efficacy of nucresiran compare...

1,250 participants
Alnylam Pharmaceuticals
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RecruitingBoston, MASSACHUSETTSNCT06481891

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

The main purpose of the study is to determine the changes in symptoms and functional limitations in participants with symptomatic hypertrophic cardiomyopathy (HCM) treated with sotagliflozin as compar...

500 participants
Lexicon Pharmaceuticals
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RecruitingBoston, MASSACHUSETTSNCT06347159

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

This study is being conducted in order to understand the safety and effects of different doses of EDG-7500 as a single dose in adults with obstructive hypertrophic cardiomyopathy (oHCM) and as multipl...

75 participants
Edgewise Therapeutics, Inc.
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RecruitingBoston, MASSACHUSETTSNCT05836259

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

This is a first-in-human, non-randomized, open-label study designed to evaluate the safety, tolerability, and pharmacodynamics (PD) of TN-201 in adult patients with symptomatic hypertrophic cardiomyop...

30 participants
Tenaya Therapeutics
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About Cardiomyopathy Clinical Trials in Boston

Cardiomyopathy refers to diseases of the heart muscle that make it harder for the heart to pump blood. Types include dilated, hypertrophic, and restrictive cardiomyopathy. Treatment depends on the type and may include medications, devices, or heart transplant.

There are currently 4 cardiomyopathy clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 1,855 participants. Research is being sponsored by Alnylam Pharmaceuticals, Lexicon Pharmaceuticals, Edgewise Therapeutics, Inc. and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Cardiomyopathy Clinical Trials in Boston — FAQ

Are there cardiomyopathy clinical trials in Boston?

Yes, there are 4 cardiomyopathy clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What cardiomyopathy treatments are being tested?

The 4 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for cardiomyopathy.

Data updated March 2, 2026 from ClinicalTrials.gov