Boston, MASSACHUSETTS7 Active Studies

Temporal Lobe Epilepsy Clinical Trials in Boston, MASSACHUSETTS

Find 7 actively recruiting temporal lobe epilepsy clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,556
Enrolling

Recruiting Temporal Lobe Epilepsy Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT06876649

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib....

787 participants
Eli Lilly and Company
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RecruitingBoston, MASSACHUSETTSNCT04787042

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab \[Gazyva®\] pre-treatme...

316 participants
Simcha IL-18, Inc.
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RecruitingBoston, MASSACHUSETTSNCT06742996

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma

The goal of this study is to compare how well sonrotoclax plus zanubrutinib works versus zanubrutinib plus placebo in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This st...

300 participants
BeiGene
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RecruitingBoston, MASSACHUSETTSNCT04855695

Avo In R/R And Previously Untreated MCL

This research study is evaluating the combination of three drugs - acalabrutinib, venetoclax, and obinutuzumab - as a possible treatment for relapsed or refractory and untreated mantle cell lymphoma (...

53 participants
Austin I Kim
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RecruitingBoston, MASSACHUSETTSNCT02934568

Ribociclib (LEE011) Rollover Study for Continued Access

This study is to allow continued use of ribociclib (LEE011) as single agent or in combination with other investigational treatments in patients benefitting from treatment in an eligible Novartis-spons...

50 participants
Novartis Pharmaceuticals
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RecruitingBoston, MASSACHUSETTSNCT05705024

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of...

38 participants
University of Illinois at Chicago
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RecruitingBoston, MASSACHUSETTSNCT06063850

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mesial temporal lobe epilepsy (MTLE)....

12 participants
UniQure Biopharma B.V.
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About Temporal Lobe Epilepsy Clinical Trials in Boston

Temporal lobe epilepsy is the most common form of focal epilepsy, with seizures originating in the temporal lobe of the brain. It can cause unusual sensations, memory problems, and altered consciousness. Treatment includes antiseizure medications and surgery for drug-resistant cases.

There are currently 7 temporal lobe epilepsy clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 1,556 participants. Research is being sponsored by Eli Lilly and Company, Simcha IL-18, Inc., BeiGene and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Temporal Lobe Epilepsy Clinical Trials in Boston — FAQ

Are there temporal lobe epilepsy clinical trials in Boston?

Yes, there are 7 temporal lobe epilepsy clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What temporal lobe epilepsy treatments are being tested?

The 7 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for temporal lobe epilepsy.

Data updated March 2, 2026 from ClinicalTrials.gov