Chapel Hill, NC15 Active Studies

Pulmonary Embolism Clinical Trials in Chapel Hill, NC

Find 15 actively recruiting pulmonary embolism clinical trials in Chapel Hill, NC. Connect with local research sites and explore new treatment options.

15
Active Trials
13
Sponsors
8,831
Enrolling

Recruiting Pulmonary Embolism Studies in Chapel Hill

NCT04774159Recruiting

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular ...

Chapel Hill, NCPHASE36,150 participantsPopulation Health Research Institute
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NCT06628453Recruiting

CGM for Management of Type 2 Diabetes in Pregnancy

The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn...

Chapel Hill, NCNA564 participantsUniversity of Alabama at Birmingham
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NCT05096923Recruiting

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

Purpose: This study aims to create a registry of childhood, adolescent, and young adult patients with cancer (\<40 years-old at cancer diagnosis), entitled the 'UNC Childhood, Adolescent, and Young Ad...

Chapel Hill, NC500 participantsUNC Lineberger Comprehensive Cancer Center
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NCT01286519Recruiting

Pharmacokinetics of Off Label Pediatric Medications

The purpose of this study is to measure the level of medicines found in body fluids such as blood, urine, spinal fluid of children....

Chapel Hill, NC400 participantsUniversity of North Carolina, Chapel Hill
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NCT06777901Recruiting

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages. The main question it aims to answer is: Is tr...

Chapel Hill, NCPHASE4224 participantsAngiodynamics, Inc.
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NCT06405373Recruiting

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

This study is designed to compare two behavioral approaches to reduce diabetes distress ("the expected burdens, concerns, fears, and threats that arise from the challenges of living with diabetes") in...

Chapel Hill, NCNA200 participantsUniversity of North Carolina, Chapel Hill
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NCT06907147Recruiting

SPYRAL GEMINI Pilot Study

The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled...

Chapel Hill, NCNA175 participantsMedtronic Vascular
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NCT05799599Recruiting

Peer Interventions for Preschoolers With Autism

This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Ass...

Chapel Hill, NCNA132 participantsUniversity of Kansas
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NCT05966467Recruiting

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Long-term, multicenter, multinational, observational, registry of patients with AQP4+ NMOSD that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor...

Chapel Hill, NC122 participantsAlexion Pharmaceuticals, Inc.
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NCT06880640Recruiting

Affect-based Impulsivity in Borderline Personality Disorder

The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old. The main question it aims to a...

Chapel Hill, NCNA106 participantsUniversity of North Carolina, Chapel Hill
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NCT06997588Recruiting

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

This study is designed to demonstrate the efficacy and assess safety and tolerability of oral daily alpelisib in participants with PIK3CA-related overgrowth spectrum (PROS)....

Chapel Hill, NCPHASE2104 participantsNovartis Pharmaceuticals
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NCT07015996Recruiting

Efficacy of Tezepelumab in Peanut Oral Immunotherapy

The proposed study is a proof-of-concept Phase 2, double-blind, randomized placebo-controlled clinical trial evaluating the safety and efficacy of tezepelumab and peanut Oral Immunotherapy (OIT) for t...

Chapel Hill, NCPHASE262 participantsNational Institute of Allergy and Infectious Diseases (NIAID)
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NCT07580898Recruiting

Safety of MOON101 for the Treatment of Peanut Allergy

The goal of this open-label, single escalating dose study in 3 sequential groups: adults, adolescents, and children with peanut allergy is to assess the safety of MOON101. The main question it aims to...

Chapel Hill, NCPHASE140 participantsMoonlight Therapeutics, Inc.
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NCT07073820Recruiting

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

The purpose of this study is to learn about the long-term safety, tolerability and effects of the study medicine (PF-07868489) for the possible treatment of PAH. PAH is a condition in which there is h...

Chapel Hill, NCPHASE236 participantsPfizer
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NCT06919354Recruiting

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

This is a 78-week single arm, multi-center, Phase 1 study to evaluate the safety, tolerability, cellular kinetics, and biomarker changes in C-peptide over time of GNTI-122, an investigational cell the...

Chapel Hill, NCPHASE116 participantsGentiBio, Inc
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About Pulmonary Embolism Clinical Trials in Chapel Hill

Pulmonary embolism (PE) is a blockage of an artery in the lungs, usually caused by blood clots that travel from the deep veins of the legs. It can be life-threatening and requires immediate medical attention. Treatment includes anticoagulants and in severe cases, thrombolytic therapy.

There are currently 15 pulmonary embolism clinical trials recruiting participants in Chapel Hill, NC. These studies are seeking a combined 8,831 participants. Research is being sponsored by Population Health Research Institute, University of Alabama at Birmingham, UNC Lineberger Comprehensive Cancer Center and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Embolism Clinical Trials in Chapel Hill — FAQ

Are there pulmonary embolism clinical trials in Chapel Hill?

Yes, there are 15 pulmonary embolism clinical trials currently recruiting in Chapel Hill, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chapel Hill?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chapel Hill research site will contact you about next steps.

Are clinical trials in Chapel Hill free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chapel Hill studies also compensate for your time and travel.

What pulmonary embolism treatments are being tested?

The 15 active trials in Chapel Hill are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary embolism.

Data updated July 18, 2026 from ClinicalTrials.gov