Chapel Hill, NC11 Active Studies

Pulmonary Hypertension Clinical Trials in Chapel Hill, NC

Find 11 actively recruiting pulmonary hypertension clinical trials in Chapel Hill, NC. Connect with local research sites and explore new treatment options.

11
Active Trials
11
Sponsors
1,125
Enrolling

Recruiting Pulmonary Hypertension Studies in Chapel Hill

RecruitingChapel Hill, NCNCT06596252

Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

The purpose of this study is to prove the non-inferiority of a 6-weeks treatment with 1 mg budesonide orodispersible tablets BID versus 2 mg budesonide orodispesible tabletss for the induction of clin...

308 participants
Dr. Falk Pharma GmbH
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RecruitingChapel Hill, NCNCT05208190

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

Two-hundred and eighty individuals with schizophrenia who have a recent history of violent acts will be randomized in this 2-arm, parallel-group, 24-week, open-label, 7-site clinical trial to examine ...

280 participants
New York State Psychiatric Institute
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RecruitingChapel Hill, NCNCT06238648

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

This phase II trial compares epcoritamab to standard practice (observation) for the treatment of patients with B-cell lymphomas who are not in complete remission after treatment with CD19-directed chi...

120 participants
Academic and Community Cancer Research United
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RecruitingChapel Hill, NCNCT05538208

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA; 600mg/m2 body surface area per dose about every ...

105 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingChapel Hill, NCNCT04895436

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess retreatment with venetoclax-obinutuzumab (VenG) in participants previousl...

75 participants
AbbVie
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RecruitingChapel Hill, NCNCT05345197

Emicizumab in Patients With Acquired Hemophilia A

This is a phase II multicenter open-label, single-arm prospective study to evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquire...

51 participants
University of Washington
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RecruitingChapel Hill, NCNCT06534060

MB-105 in Patients With CD5 Positive T-cell Lymphoma

This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon tw...

46 participants
March Biosciences Inc
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RecruitingChapel Hill, NCNCT05288855

Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis

The purpose of this study is to assess the efficacy and safety of voclosporin compared to placebo in achieving renal response following 24 weeks of therapy in adolescent and pediatric subjects with ac...

40 participants
Aurinia Pharmaceuticals Inc.
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RecruitingChapel Hill, NCNCT05654506

Daratumumab for Treatment of Proliferative Glomerulonephritis With Monoclonal Immune Deposits

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in people with proliferative glomerulonephritis with monoclonal immunoglobulin...

40 participants
Mayo Clinic
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RecruitingChapel Hill, NCNCT06239480

SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations

SELVA: A Multicenter, Phase 3 Baseline-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations The main purp...

40 participants
Palvella Therapeutics, Inc.
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RecruitingChapel Hill, NCNCT04083495

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

This is a research study to determine the safety and tolerability of ATLCAR.CD30 for treating relapsed/refractory Peripheral T Cell Lymphoma. Blood samples will be collected from study participants an...

20 participants
UNC Lineberger Comprehensive Cancer Center
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About Pulmonary Hypertension Clinical Trials in Chapel Hill

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 11 pulmonary hypertension clinical trials recruiting participants in Chapel Hill, NC. These studies are seeking a combined 1,125 participants. Research is being sponsored by Dr. Falk Pharma GmbH, New York State Psychiatric Institute, Academic and Community Cancer Research United and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Chapel Hill — FAQ

Are there pulmonary hypertension clinical trials in Chapel Hill?

Yes, there are 11 pulmonary hypertension clinical trials currently recruiting in Chapel Hill, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chapel Hill?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chapel Hill research site will contact you about next steps.

Are clinical trials in Chapel Hill free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chapel Hill studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 11 active trials in Chapel Hill are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov