14 Rheumatoid Arthritis Clinical Trials in Charlotte, MI (2026)

Q: Are there rheumatoid arthritis clinical trials in Charlotte?

Yes, there are 14 rheumatoid arthritis clinical trials currently recruiting in Charlotte, MI.

Q: How do I join a clinical trial in Charlotte?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlotte research site will contact you.

Q: Are clinical trials in Charlotte free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Rheumatoid Arthritis Studies in Charlotte

NCT05936970Recruiting

Prospective, Multi-Center, Observational, Whole Blood Specimen Collection Study in Participants with Rheumatoid Arthritis with Inadequate Response or Intolerance to a DMARD Starting a New BDMARD or TsDMARD Treatment +/- CsDMARD

The primary goal of this study is to assess a cfDNA-based blood test using genetic, transcriptomic and/or epigenetic information to help doctors predict the best treatment options for rheumatoid arthr...

Charlotte, MI1,410 participantsAqtual, Inc.

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NCT05437575Recruiting

Prehospital Analgesia INtervention Trial (PAIN)

The Prehospital Analgesia INtervention trial (PAIN) is a proposed 4 year (3-year enrollment) multicenter, prehospital, randomized, double-blind, clinical trial that will enroll approximately 994 patie...

Charlotte, MI994 participantsJason Sperry

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NCT05766670Recruiting

Intramedullary Calcium Sulfate Antibiotic Depot

The goal of this randomized clinical trial is to study the best treatment for open lower leg fractures to prevent infection. The main questions it aims to answer is if treating tibia fracture patients...

Charlotte, MI497 participantsWake Forest University Health Sciences

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NCT05421741Recruiting

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

This prospective randomized clinical trial will compare outcomes between patients treated primarily with a prophylactic antibiotic coated nail and those treated with traditional standard of care intra...

Charlotte, MI484 participantsWake Forest University Health Sciences

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NCT05897320Recruiting

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine

The main goal of this trial is to learn whether eptinezumab helps reduce the number of days with episodic migraine in pediatric participants....

Charlotte, MI315 participantsH. Lundbeck A/S

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NCT06616194Recruiting

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

The purpose of this study is to learn about the effect of a study medicine called rimegepant in adolescents who have frequent migraine attacks. Rimegepant is a tablet that dissolves when you put it o...

Charlotte, MI200 participantsPfizer

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NCT04615104Recruiting

Pelvic and Acetabular Fracture: A Prospective Observational Study

The purpose of this study is to understand the trajectory of function and self-reported outcomes of patients following pelvic and acetabular, treated both operatively and nonoperatively....

Charlotte, MI200 participantsWake Forest University Health Sciences

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NCT07131631Recruiting

Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance

This is a multi-center, prospective, observational study designed to evaluate the impact of LV myocardial fibrosis extent assessed by CMR on LV reverse remodeling and clinical outcomes post TEER. The ...

Charlotte, MI125 participantsMinneapolis Heart Institute Foundation

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NCT06636656Recruiting

A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis

Adults between 18 and 80 years of age with ulcerative colitis can participate in this study. This is a study for people for whom previous treatment was not successful or who stopped previous treatment...

Charlotte, MI80 participantsBoehringer Ingelheim

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NCT06985147Recruiting

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics...

Charlotte, MI60 participantsDisc Medicine, Inc

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NCT07124078Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

This study will be conducted to compare Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy....

Charlotte, MI60 participantsIncyte Corporation

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NCT04789044Recruiting

Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury. PEG is s...

Charlotte, MI40 participantsMajor Extremity Trauma Research Consortium

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NCT06321601Recruiting

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV....

Charlotte, MI20 participantsAmgen

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NCT06392386Recruiting

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

The purpose of this study is to measure the pharmacokinetics (PK), pharmacodynamics (PD), safety, tolerability, and immunogenicity of efgartigimod PH20 SC in pediatric participants with gMG aged 2 to ...

Charlotte, MI12 participantsargenx

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About Rheumatoid Arthritis Clinical Trials in Charlotte

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 14 rheumatoid arthritis clinical trials recruiting participants in Charlotte, MI. These studies are seeking a combined 4,497 participants. Research is being sponsored by Aqtual, Inc., Jason Sperry, Wake Forest University Health Sciences and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Charlotte — FAQ

Are there rheumatoid arthritis clinical trials in Charlotte?

Yes, there are 14 rheumatoid arthritis clinical trials currently recruiting in Charlotte, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Charlotte?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlotte research site will contact you about next steps.

Are clinical trials in Charlotte free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Charlotte studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 14 active trials in Charlotte are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated July 13, 2026 from ClinicalTrials.gov