13 Leukemia Clinical Trials in Charlottesville, VA (2026)

Q: How do I join a clinical trial in Charlottesville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlottesville research site will contact you.

Recruiting Leukemia Studies in Charlottesville

NCT05732103Recruiting

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

The goal of this phase 1/2 multicenter, open-label, single-arm dose escalation and expansion study is to assess the safety, tolerability, pharmacokinetic and pharmacodynamic profile of CTX-712 in pati...

Charlottesville, VAPHASE1225 participantsChordia Therapeutics, Inc.

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NCT07504458Recruiting

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

This Phase 3 study in adult participants with newly diagnosed low-risk APL will evaluate the efficacy, safety, and PK of an oral capsule formulation of ATO, in combination with ATRA....

Charlottesville, VAPHASE3150 participantsQuetzal Therapeutics

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NCT05903092Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer

The study treatment will consist of a platinum drug (carboplatin or cisplatin per investigator's choice) plus etoposide plus durvalumab plus monalizumab every 3 weeks for 4 cycles. After 4 cycles, sub...

Charlottesville, VAPHASE284 participantsHirva Mamdani

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NCT06965114Recruiting

Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell Leukemia

This phase I/II trial tests the safety, side effects, and effectiveness of tovorafenib in combination with rituximab in patients with classical hairy cell leukemia (cHCL) that has come back after a pe...

Charlottesville, VAPHASE184 participantsNational Cancer Institute (NCI)

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NCT04977180Recruiting

Cardioprotection in AML

Patients with acute myeloid leukemia (AML) often receive a drug called daunorubicin. Daunorubicin is a type of drug called an anthracycline, which increases the risk of some damage to the heart. Beta ...

Charlottesville, VAPHASE270 participantsUniversity of Virginia

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NCT07149363Recruiting

Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

This is a phase II trial of adjuvant chemotherapy and immunotherapy for completely resected small cell lung cancer (SCLC)....

Charlottesville, VAPHASE265 participantsAlliance Foundation Trials, LLC.

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NCT07057791Recruiting

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

Eligible untreated participants with Extensive Stage Small Cell Lung Cancer (ES-SCLC) who are ≥ 18 years of age will be randomized to receive ivonescimab 10 milligrams per kilogram (mg/kg) or ivonesci...

Charlottesville, VAPHASE260 participantsPrECOG, LLC.

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NCT06382168Recruiting

DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

This Phase I/II trial evaluates the safety and preliminary efficacy of DFP-10917 combined with venetoclax in relapsed or refractory acute myeloid leukemia. DFP-10917 is given as a 14-day continuous IV...

Charlottesville, VAPHASE139 participantsDelta-Fly Pharma, Inc.

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NCT07012031Recruiting

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

This phase I/II trial tests the safety, side effects and best dose of sotorasib with trastuzumab deruxtecan and how well the combination works in treating patients with KRAS G12C mutated non-small cel...

Charlottesville, VAPHASE137 participantsNational Cancer Institute (NCI)

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NCT06248606Recruiting

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

This is a single arm phase 2 trial is to evaluate the efficacy of SRS plus adagrasib for the treatment of brain metastases for patients with KRAS G12C-mutated non-small cell lung cancer (NSCLC). A tot...

Charlottesville, VAPHASE230 participantsRyan Gentzler, MD

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NCT07270978Recruiting

Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS

The purpose of this study is to understand the safety and estimate the efficacy of combining anti-CD3 x anti-CD33 bispecific antibody (CD33Bi) armed fresh peripheral blood mononuclear cells (CD33Bi FP...

Charlottesville, VAPHASE123 participantsUniversity of Virginia

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NCT06449313Recruiting

Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node Involvement

The goal of this clinical trial is to learn about neoadjuvant cemiplimab with histology-specific chemotherapy followed by resection and adjuvant cemiplimab in stage 3 non-small cell lung cancer (NSCLC...

Charlottesville, VAPHASE221 participantsGeorgetown University

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NCT04716452Recruiting

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

The study objective is to evaluate patient safety for patients with refractory and relapsed AML being treated with Ceramide NanoLiposome (CNL) ....

Charlottesville, VAPHASE115 participantsKeystone Nano, Inc

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About Leukemia Clinical Trials in Charlottesville

Leukemia is a group of blood cancers that develop in the bone marrow and result in abnormal white blood cells. Types include acute myeloid (AML), acute lymphoblastic (ALL), chronic myeloid (CML), and chronic lymphocytic (CLL). Treatment varies by type and may include chemotherapy, targeted therapy, and stem cell transplant.

There are currently 13 leukemia clinical trials recruiting participants in Charlottesville, VA. These studies are seeking a combined 903 participants. Research is being sponsored by Chordia Therapeutics, Inc., Quetzal Therapeutics, Hirva Mamdani and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Leukemia Clinical Trials in Charlottesville — FAQ

Are there leukemia clinical trials in Charlottesville?

Yes, there are 13 leukemia clinical trials currently recruiting in Charlottesville, VA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Charlottesville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlottesville research site will contact you about next steps.

Are clinical trials in Charlottesville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Charlottesville studies also compensate for your time and travel.

What leukemia treatments are being tested?

The 13 active trials in Charlottesville are testing new therapies including novel drugs, biologics, and treatment approaches for leukemia.

Data updated July 19, 2026 from ClinicalTrials.gov