13 COPD Clinical Trials in Chicago, IL (2026)

Q: How do I join a clinical trial in Chicago?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you.

Recruiting COPD Studies in Chicago

NCT04543461Recruiting

American Lung Association (ALA) Lung Health Cohort

The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of t...

Chicago, IL4,000 participantsJohns Hopkins University

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NCT00470327Recruiting

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

We propose to acquire data and blood samples on all patients being cared for by the Interstitial Lung Disease (ILD) program. Additionally, we will collect data and blood samples from a control group f...

Chicago, IL4,000 participantsUniversity of Chicago

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NCT06177717Recruiting

Deep Functional Phenotyping of the ALA Lung Health Cohort

The goal of this observational study is to learn about lung structure and function in a group of 1000 healthy people aged 25 to 35. The main questions it aims to answer are whether people's bodies, en...

Chicago, IL1,000 participantsJohns Hopkins University

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NCT05033990Recruiting

SPIROMICS Study of Early COPD Progression (SOURCE)

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals:...

Chicago, IL1,000 participantsUniversity of Massachusetts, Worcester

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NCT05204888Recruiting

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year a...

Chicago, ILNA642 participantsTemple University

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NCT07125053Recruiting

COPD Resources, Education, and Activity Designed for You Study

Although COPD self-management treatment programs are effective in reducing COPD-related hospitalizations and increasing quality of life, there is a limited understanding of 'how and why' they work. Th...

Chicago, ILNA448 participantsRush University Medical Center

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NCT06390345Recruiting

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

The investigators will conduct a Type I hybrid effectiveness-implementation study to test an integrated telehealth intervention among 400 overweight and obese patients with Chronic Obstructive Pulmona...

Chicago, ILNA400 participantsSeattle Institute for Biomedical and Clinical Research

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NCT07285655Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD

The purpose of this study is to find out if L606 is safe and if it helps people with high blood pressure in the lungs (pulmonary hypertension) caused by interstitial lung disease (PH-ILD, WHO Group 3)...

Chicago, ILPHASE3344 participantsLiquidia Technologies, Inc.

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NCT07059091Recruiting

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Each participant will be in the study for about 16 mon...

Chicago, ILPHASE2334 participantsJohns Hopkins University

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NCT06891755Recruiting

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphys...

Chicago, ILNA250 participantsApreo Health, Inc.

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NCT06035120Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo ...

Chicago, ILNA200 participantsPulmonx Corporation

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NCT04302272Recruiting

STRIVE Post-Market Registry Study

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-m...

Chicago, IL150 participantsOlympus Corporation of the Americas

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NCT07119229Recruiting

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

A study taking place at multiple sites in the United States, Europe and Brazil to evaluate how well a new therapy for severe COPD/emphysema works, and how safe it is....

Chicago, ILNA60 participantsPulmair Medical, Inc.

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About COPD Clinical Trials in Chicago

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes breathing difficult, primarily caused by smoking. It includes emphysema and chronic bronchitis. Treatment involves bronchodilators, inhaled steroids, pulmonary rehabilitation, and oxygen therapy.

There are currently 13 copd clinical trials recruiting participants in Chicago, IL. These studies are seeking a combined 12,828 participants. Research is being sponsored by Johns Hopkins University, University of Chicago, University of Massachusetts, Worcester and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

COPD Clinical Trials in Chicago — FAQ

Are there copd clinical trials in Chicago?

Yes, there are 13 copd clinical trials currently recruiting in Chicago, IL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chicago?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you about next steps.

Are clinical trials in Chicago free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chicago studies also compensate for your time and travel.

What copd treatments are being tested?

The 13 active trials in Chicago are testing new therapies including novel drugs, biologics, and treatment approaches for copd.

Data updated July 17, 2026 from ClinicalTrials.gov