7 PTSD Clinical Trials in Chicago, IL (2026)

Q: How do I join a clinical trial in Chicago?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you.

Recruiting PTSD Studies in Chicago

NCT06479447Recruiting

Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

This study aims to implement and evaluate a more timely approach to post-traumatic stress disorder (PTSD) diagnosis and management, entitled Patient Outcome Reporting for Timely Assessments of Life wi...

Chicago, ILNA17,000 participantsUniversity of Chicago

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NCT06733376Recruiting

Evaluating Evidenced Based Options for PTSD Treatment

This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment. The goal is t...

Chicago, ILNA400 participantsRush University Medical Center

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NCT05700279Recruiting

Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset

Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain. Untreate...

Chicago, ILNA345 participantsRush University Medical Center

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NCT07570654Recruiting

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring and support from a trained study team. COM...

Chicago, ILPHASE2300 participantsCOMPASS Pathways

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NCT06570213Recruiting

Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD

The purpose of this study is to understand if we can improve the treatment for posttraumatic stress disorder (PTSD). We are looking into whether the combination of Stellate Ganglion Block (SGB) treatm...

Chicago, ILEARLY_PHASE1270 participantsRush University Medical Center

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NCT07430657Recruiting

Nurse-Led PTSD Treatment in Primary Care

Purpose of the Study Post-traumatic stress disorder (PTSD) is a common and serious condition, but many people cannot get the help they need because there are not enough mental health specialists (like...

Chicago, ILNA100 participantsRush University Medical Center

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NCT07865052Recruiting

Psychological Prehabilitation for Complex Gastrointestinal Surgery

The goal of this clinical trial is to learn if a psychological program before surgery can help adults who have lasting stress from past medical experiences. The program is called PREPARE-GI. It is for...

Chicago, ILNA20 participantsNorthwestern University

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About PTSD Clinical Trials in Chicago

Post-traumatic stress disorder (PTSD) is a mental health condition triggered by experiencing or witnessing a traumatic event. Symptoms include flashbacks, nightmares, severe anxiety, and uncontrollable thoughts. Treatment includes trauma-focused psychotherapy and medications.

There are currently 7 ptsd clinical trials recruiting participants in Chicago, IL. These studies are seeking a combined 18,435 participants. Research is being sponsored by University of Chicago, Rush University Medical Center, COMPASS Pathways and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

PTSD Clinical Trials in Chicago — FAQ

Are there ptsd clinical trials in Chicago?

Yes, there are 7 ptsd clinical trials currently recruiting in Chicago, IL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Chicago?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Chicago research site will contact you about next steps.

Are clinical trials in Chicago free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Chicago studies also compensate for your time and travel.

What ptsd treatments are being tested?

The 7 active trials in Chicago are testing new therapies including novel drugs, biologics, and treatment approaches for ptsd.

Data updated October 12, 2026 from ClinicalTrials.gov