16 Advanced Solid Tumors Clinical Trials in Cincinnati, OH (2026)

Q: How do I join a clinical trial in Cincinnati?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Cincinnati research site will contact you.

Recruiting Advanced Solid Tumors Studies in Cincinnati

NCT06384352Recruiting

Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

This is a multicenter, open-label, Phase 1 study. The study will enroll subjects with advanced solid tumors. It consists of six parts. Objectives for Dose-Escalation Parts (Part 1 and Part 4) To evalu...

Cincinnati, OHPHASE1500 participantsMediLink Therapeutics (Suzhou) Co., Ltd.

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NCT06241456Recruiting

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

This is a phase 1 study designed to evaluate the safety, tolerability, and antitumor activity of FT825 (also known as ONO-8250) with or without monoclonal antibody therapy following chemotherapy in pa...

Cincinnati, OHPHASE1351 participantsFate Therapeutics

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NCT05720117Recruiting

A Study of PYX-201 in Advanced Solid Tumors

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with recurrent/metastatic (R/M) solid tumors, and to determine the objective response rate (OR...

Cincinnati, OHPHASE1330 participantsPyxis Oncology, Inc

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NCT06234397Recruiting

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

This is a First-in-Human, Phase 1, Dose-Escalation and Dose-Expansion study of BH3120, as a single agent and in combination with pembrolizumab, to assess safety, tolerability, MTD, RP2D, PK, and effic...

Cincinnati, OHPHASE1245 participantsHanmi Pharmaceutical Company Limited

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NCT06480552Recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

The primary objectives of this trial are to: * Characterize the safety and tolerability of TEV-56278 * Determine the Recommended Phase 2 Dose (RP2D) * Evaluate antitumor activity of TEV-56278 (Part 2...

Cincinnati, OHPHASE1240 participantsTeva Branded Pharmaceutical Products R&D LLC

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NCT06859762Recruiting

A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

A Phase 1 First-in-Human study of YL217 in Patients with Advanced Solid Tumors...

Cincinnati, OHPHASE1220 participantsMediLink Therapeutics (Suzhou) Co., Ltd.

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NCT06425926Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

GIM-531 is a first-in-class, orally bioavailable small molecule that is being developed for the treatment of advanced solid tumors as a single agent and rescue therapy. GIM-531 exhibits its primary ef...

Cincinnati, OHPHASE1117 participantsGeorgiamune Inc

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NCT04872166Recruiting

A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

This is a multicenter, open label, nonrandomized, sequential dose escalation/dose ranging, multiple dose study designed to evaluate the safety, toxicity, and PK as well as preliminary efficacy of BTX-...

Cincinnati, OHPHASE1112 participantsEdgewood Oncology Inc.

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NCT06507306Recruiting

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

The goal of this clinical trial is to learn if KQB198 works to treat advanced solid tumor cancer in adults. It will also learn about the safety of KQB198. The main questions it aims to answer are: * ...

Cincinnati, OHPHASE1100 participantsKumquat Biosciences Inc.

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NCT07207707Recruiting

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

The goal of this trial is to learn if KQB548 works to treat patients with advanced solid malignancies with a KRAS G12D mutation. It will also learn about the safety of KQB548. The main questions it ai...

Cincinnati, OHPHASE178 participantsKumquat Biosciences Inc.

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NCT05038150Recruiting

Study of SGN1 in Patients With Advanced Solid Tumor

Objectives:To assess the safety and tolerability followed by a dose expansion study to characterize safety, and preliminary efficacy of SGN1 in participants with refractory solid tumors. Study Ration...

Cincinnati, OHPHASE170 participantsGuangzhou Sinogen Pharmaceutical Co., Ltd

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NCT06096974Recruiting

Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

This study will evaluate the safety, tolerability, drug levels, pharmacodynamic effects, and clinical activity of YL 17231 in patients with advanced solid tumors harboring mutations in KRAS, HRAS, or ...

Cincinnati, OHPHASE160 participantsShanghai YingLi Pharmaceutical Co. Ltd.

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NCT06463340Recruiting

Study of SGR-3515 In Participants With Advanced Solid Tumors.

The purpose of this study is to learn about the effects of a new study drug, called SGR-3515 that may be a treatment for advanced solid tumors....

Cincinnati, OHPHASE152 participantsSchrödinger, Inc.

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NCT04928677Recruiting

A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

The purpose of this study to find out whether codrituzumab is a safe treatment that causes few or mild side effects in children and young adults who have solid tumors that express the protein GPC3. Th...

Cincinnati, OHPHASE150 participantsMemorial Sloan Kettering Cancer Center

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NCT06187402Recruiting

A Study of LM-24C5 For Advanced Solid Tumors

To assess the safety and tolerability, obtain the recommended phase 2 dose (RP2D)/optimal biologic dose (OBD) and/or Maximum Tolerated Dose (MTD) for LM-24C5 in subjects with advanced solid tumors....

Cincinnati, OHPHASE149 participantsLaNova Medicines Limited

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NCT05868629Recruiting

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

This study is a phase IV, pragmatic single-arm prospective, open label study in pediatric (1 years or older) and adult study participants with rare BRAF V600E mutation-positive unresectable or metasta...

Cincinnati, OH40 participantsNovartis Pharmaceuticals

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About Advanced Solid Tumors Clinical Trials in Cincinnati

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 16 advanced solid tumors clinical trials recruiting participants in Cincinnati, OH. These studies are seeking a combined 2,614 participants. Research is being sponsored by MediLink Therapeutics (Suzhou) Co., Ltd., Fate Therapeutics, Pyxis Oncology, Inc and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Cincinnati — FAQ

Are there advanced solid tumors clinical trials in Cincinnati?

Yes, there are 16 advanced solid tumors clinical trials currently recruiting in Cincinnati, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cincinnati?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cincinnati research site will contact you about next steps.

Are clinical trials in Cincinnati free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cincinnati studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 16 active trials in Cincinnati are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated July 18, 2026 from ClinicalTrials.gov