27 Heart Attack Clinical Trials in Cleveland, OH (2026)

Q: How do I join a clinical trial in Cleveland?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you.

Recruiting Heart Attack Studies in Cleveland

NCT04669548Recruiting

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular ...

Cleveland, OH2,500 participantsPotrero Medical

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NCT00921986Recruiting

Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes....

Cleveland, OH2,000 participantsThe Cleveland Clinic

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NCT01694940Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders....

Cleveland, OH1,000 participantsColumbia University

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NCT06854458Recruiting

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the h...

Cleveland, OHNA1,000 participantsBrigham and Women's Hospital

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NCT05071144Recruiting

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine de...

Cleveland, OH700 participantsBoston Children's Hospital

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NCT04064060Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

A Phase 3b, open-label, single-arm, rollover study to evaluate the long-term safety of luspatercept, to the following participants: * Participants receiving luspatercept on a parent protocol at the t...

Cleveland, OHPHASE3665 participantsCelgene

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NCT05868902Recruiting

A Registry of Cardiac PET and CardioFlux Magnetocardiography in Patients With Suspected Coronary Ischemia.

A multicenter observational data development registry collecting diagnostic measures via standard of care (SOC) cardiac PET in order gain a better understanding of how CardioFlux MCG may be used in th...

Cleveland, OH300 participantsGenetesis Inc.

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NCT03209583Recruiting

ATrial Tachycardia PAcing Therapy in Congenital Heart

Congenital heart disease (CHD) affects approximately 1% of newborns in the US, with 25% of those affected having critical conditions requiring open heart surgery within one year of birth. Surgical and...

Cleveland, OH300 participantsIan Law

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NCT06258447Recruiting

CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction

Concentrated autologous bone marrow mononuclear cells (ABM MNC) contain potentially therapeutic cell factors and past studies support therapeutic benefit to patients with cardiac diseases of acute myo...

Cleveland, OHNA250 participantsBioCardia, Inc.

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NCT04260022Recruiting

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic pha...

Cleveland, OHPHASE1242 participantsAscentage Pharma Group Inc.

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NCT06093672Recruiting

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

The goal of this clinical trial is to compare the efficacy and safety of givinostat to hydroxyurea in Jak2V617F-positive high risk polycythemia vera patients....

Cleveland, OHPHASE3220 participantsItalfarmaco

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NCT07220382Recruiting

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (...

Cleveland, OHPHASE4188 participantsThe Cleveland Clinic

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NCT07208162Recruiting

SHARE Adaptation Intervention for African-American Families

This project aims to culturally adapt the SHARE program for African-Americans in early-moderate stage dementia and their care partner. Upon completion of the adaptation, a pilot randomized-control tri...

Cleveland, OHNA120 participantsBenjamin Rose Institute on Aging

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NCT06409156Recruiting

EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery

The investigators propose a single-center, assessor blinded, randomized control trial to compare the efficacy of external oblique fascial plane (EOIFP) block versus Oblique Subcostal Transversus Abdom...

Cleveland, OHNA100 participantsThe Cleveland Clinic

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NCT07088510Recruiting

Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

Early pregnancy loss happens when a pregnancy that is not developing properly is found on an ultrasound before 12 weeks and 6 days. This type of loss occurs in about 10% of pregnancies. There are thre...

Cleveland, OHNA80 participantsUniversity Hospitals Cleveland Medical Center

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NCT06795035Recruiting

Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution

The goal of this observational study to measure the heart's microvascular function in the setting of a myocardial infarction (MI), or heart attack, using a method called continuous saline thermodiluti...

Cleveland, OH70 participantsThe Cleveland Clinic

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NCT06918431Recruiting

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

This phase II trial tests the safety, side effects, and effectiveness of asparaginase Erwinia chrysanthemi during induction chemotherapy followed by consolidation chemotherapy in treating high-risk ad...

Cleveland, OHPHASE253 participantsCity of Hope Medical Center

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NCT04991831Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD) using the Exablate Neuro system....

Cleveland, OH50 participantsInSightec

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NCT03004326Recruiting

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis....

Cleveland, OH50 participantsPeter Merkel

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NCT03104491Recruiting

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely be given to subjects ...

Cleveland, OHPHASE144 participantsLeland Metheny

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NCT05677802Recruiting

Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cancer

This clinical trial aims to see if patients with triple negative breast cancer can complete a biobehavioral stress reduction program that also addresses health related social needs (e.g., utilities, t...

Cleveland, OHNA40 participantsOhio State University Comprehensive Cancer Center

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NCT06641310Recruiting

Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

The purpose of this phase 1a/b trial is to find out what amount of exercise would be best to use for preventing recurrence of colorectal polyps. It involves following one of four different amounts of ...

Cleveland, OHNA32 participantsUniversity of Michigan Rogel Cancer Center

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NCT05892614Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

This is a 2-Part study with Part A, a double-blind, randomized, placebo-controlled, PoC study to evaluate the efficacy, safety, and tolerability of efzofitimod in patients with SSc-ILD. The primary ob...

Cleveland, OHPHASE225 participantsaTyr Pharma, Inc.

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NCT06344143Recruiting

Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma

The aim of the proposed study is to estimate the incidence of Mild Autonomous Cortisol Secretion (MACS) in patients with Adrenal Incidentaloma (AI) and evaluate the available diagnostic tests to deter...

Cleveland, OH20 participantsThe Cleveland Clinic

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NCT07454174Recruiting

Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease

This is a 16 week pilot study of the impact of a nutritionist led ketogenic diet (Ren-Nu) supplemented with the medical food KetoCitra on autosomal dominant polycystic kidney disease....

Cleveland, OHNA20 participantsRichard Fatica

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NCT07148089Recruiting

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

This is a Phase 1b, Multicenter, Open-Label, Dose Finding Study to Investigate the Safety and Tolerability of a Single Intravenous Dose of SGT-501 in participants with catecholaminergic polymorphic ve...

Cleveland, OHPHASE118 participantsSolid Biosciences Inc.

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NCT04430218Recruiting

Peripheral Interfaces in Amputees for Sensorimotor Integration

The purpose of this research is to gather information on the safety and effectiveness of an implanted wireless sensory enabled highly intuitive controlled prosthetic device....

Cleveland, OHNA15 participantsVA Office of Research and Development

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About Heart Attack Clinical Trials in Cleveland

A heart attack (myocardial infarction) occurs when blood flow to part of the heart muscle is blocked, usually by a blood clot. It is a medical emergency requiring immediate treatment. Long-term management includes medications, lifestyle changes, and cardiac rehabilitation.

There are currently 27 heart attack clinical trials recruiting participants in Cleveland, OH. These studies are seeking a combined 10,102 participants. Research is being sponsored by Potrero Medical, The Cleveland Clinic, Columbia University and 20 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Attack Clinical Trials in Cleveland — FAQ

Are there heart attack clinical trials in Cleveland?

Yes, there are 27 heart attack clinical trials currently recruiting in Cleveland, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What heart attack treatments are being tested?

The 27 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for heart attack.

Data updated September 1, 2026 from ClinicalTrials.gov