Cleveland, OH6 Active Studies

Myeloproliferative Neoplasms Clinical Trials in Cleveland, OH

Find 6 actively recruiting myeloproliferative neoplasms clinical trials in Cleveland, OH. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
565
Enrolling

Recruiting Myeloproliferative Neoplasms Studies in Cleveland

RecruitingCleveland, OHNCT06093672

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

The goal of this clinical trial is to compare the efficacy and safety of givinostat to hydroxyurea in Jak2V617F-positive high risk polycythemia vera patients....

220 participants
Italfarmaco
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RecruitingCleveland, OHNCT05320198

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofi...

150 participants
Disc Medicine, Inc
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RecruitingCleveland, OHNCT05980806

A Study of Selinexor Monotherapy in Subjects with JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

The main purpose of this study with corresponding optional expansion is to evaluate the efficacy of selinexor in JAKi-naïve participants with myelofibrosis (MF) and moderate thrombocytopenia based on ...

118 participants
Karyopharm Therapeutics Inc
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RecruitingCleveland, OHNCT06773195

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

37 participants
Memorial Sloan Kettering Cancer Center
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RecruitingCleveland, OHNCT05835466

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

This is an open label, phase II study to assess the efficacy, safety, and tolerability of Reparixin in patients with DIPSS intermediate-2, or high-risk primary myelofibrosis (PMF), post essential thro...

26 participants
Icahn School of Medicine at Mount Sinai
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RecruitingCleveland, OHNCT05467800

Study of Canakinumab in Patients With Myelofibrosis

This is an open label, multicenter, phase 2 trial of Canakinumab in patients with primary myelofibrosis (PMF), post essential thrombocythemia/polycythemia vera related MF (Post ET/PV MF). Eligible pat...

14 participants
John Mascarenhas
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About Myeloproliferative Neoplasms Clinical Trials in Cleveland

Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.

There are currently 6 myeloproliferative neoplasms clinical trials recruiting participants in Cleveland, OH. These studies are seeking a combined 565 participants. Research is being sponsored by Italfarmaco, Disc Medicine, Inc, Karyopharm Therapeutics Inc and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myeloproliferative Neoplasms Clinical Trials in Cleveland — FAQ

Are there myeloproliferative neoplasms clinical trials in Cleveland?

Yes, there are 6 myeloproliferative neoplasms clinical trials currently recruiting in Cleveland, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What myeloproliferative neoplasms treatments are being tested?

The 6 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.

Data updated March 2, 2026 from ClinicalTrials.gov