Cleveland, OHIO6 Active Studies

Breast Cancer Clinical Trials in Cleveland, OHIO

Find 6 actively recruiting breast cancer clinical trials in Cleveland, OHIO. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
878
Enrolling

Recruiting Breast Cancer Studies in Cleveland

RecruitingCleveland, OHIONCT05867251

Study of AVZO-021 in Patients With Advanced Solid Tumors

This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients...

430 participants
Avenzo Therapeutics, Inc.
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RecruitingCleveland, OHIONCT06184750

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

This phase II trial evaluates response-guided low-dose tamoxifen for reducing breast density in women who are at higher than average risk for breast cancer. Increasing breast density is a well establi...

200 participants
National Cancer Institute (NCI)
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RecruitingCleveland, OHIONCT05900986

LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer

The aim of this Phase 1b/2 study is to investigate the safety, efficacy, and pharmacokinetics (PK) of a single dose of LS301-IT, a novel fluorescence imaging agent developed by Integro Theranostics (I...

100 participants
Integro Theranostics
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RecruitingCleveland, OHIONCT06129747

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments. The purpo...

55 participants
Case Comprehensive Cancer Center
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RecruitingCleveland, OHIONCT05455619

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

This is a Phase 1b/2, open-label, parallel-arms pilot study in men and post-menopausal women with hormone receptor positive (HR+), HER2- advanced or metastatic breast cancer with an alteration in the ...

52 participants
SynDevRx, Inc.
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RecruitingCleveland, OHIONCT04711824

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

This study is a Phase I/II study evaluating the safety and effectiveness of focused radiation therapy (radiosurgery) together with olaparib, followed by immunotherapy, for patients with brain metastas...

41 participants
Colette Shen
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About Breast Cancer Clinical Trials in Cleveland

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 6 breast cancer clinical trials recruiting participants in Cleveland, OHIO. These studies are seeking a combined 878 participants. Research is being sponsored by Avenzo Therapeutics, Inc., National Cancer Institute (NCI), Integro Theranostics and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Cleveland — FAQ

Are there breast cancer clinical trials in Cleveland?

Yes, there are 6 breast cancer clinical trials currently recruiting in Cleveland, OHIO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Cleveland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Cleveland research site will contact you about next steps.

Are clinical trials in Cleveland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Cleveland studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 6 active trials in Cleveland are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov