14 Obesity Clinical Trials in Columbia, MD (2026)

Q: Are there obesity clinical trials in Columbia?

Yes, there are 14 obesity clinical trials currently recruiting in Columbia, MD.

Q: How do I join a clinical trial in Columbia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbia research site will contact you.

Q: Are clinical trials in Columbia free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Obesity Studies in Columbia

NCT06105957Recruiting

Optimal Digital Weight Loss Treatment for Rural Individuals

Over 130 million adults in the US experience overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases. Although lifestyle interventio...

Columbia, MD616 participantsUniversity of South Carolina

View Study Details

NCT07282340Recruiting

Phentermine's Impact on Treatment in Teens

PhITT is a Phase IIb, multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of phentermine (16 mg daily) in adolescents aged 12 to \<18 years with...

Columbia, MD240 participantsRussell McCulloh, MD

View Study Details

NCT07446998Recruiting

Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss

The primary objective of this study is to assess the effect of enobosarm on total body weight...

Columbia, MD200 participantsVeru Inc.

View Study Details

NCT06132477Recruiting

Impact GLP-1 Agonists Following Bariatric

Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control hunger, induce satiety and ...

Columbia, MD150 participantsUniversity of Missouri-Columbia

View Study Details

NCT07083557Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to p...

Columbia, MD100 participantsBettina Mittendorfer

View Study Details

NCT06286761Recruiting

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)

Columbia, MD100 participantsBettina Mittendorfer

View Study Details

NCT05219799Recruiting

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system....

Columbia, MD72 participantsUniversity of Missouri-Columbia

View Study Details

NCT06335771Recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity. The ...

Columbia, MD60 participantsBettina Mittendorfer

View Study Details

NCT07340125Recruiting

Pistachio Snacking and Metabolic Flexibility

The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Se...

Columbia, MD60 participantsUniversity of South Carolina

View Study Details

NCT06745063Recruiting

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

The study will assign participants to take either the medication, empagliflozin or a placebo for 12 weeks. The goal of the study is to determine the effects of empagliflozin on arterial health in Vete...

Columbia, MD50 participantsVA Office of Research and Development

View Study Details

NCT07313384Recruiting

Dietary Insights and Nutrition Experiences in Adults on GLP-1 Therapy - A Study on Diet Quality Changes in Adults on GLP-1 Therapy

The DINE-GLP1 study aims to understand how people on GLP-1 therapy change their eating habits and what kind of dietary support they need. As more people use GLP-1 medications, there's not much guidanc...

Columbia, MD50 participantsUniversity of South Carolina

View Study Details

NCT07231484Recruiting

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity....

Columbia, MD50 participantsUniversity of Missouri-Columbia

View Study Details

NCT07518407Recruiting

Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy

This pilot study will evaluate the feasibility, acceptability, and perceived usefulness of the SWITCH mobile nutrition behavioral intervention among adults receiving GLP-1 receptor agonist therapy for...

Columbia, MD50 participantsUniversity of South Carolina

View Study Details

NCT06969235Recruiting

Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment

The objectives of this open trial feasibility study are to examine the impacts of intensive health behavior and lifestyle treatment (IHBLT) on youth and caregiver executive functioning (EF), weight st...

Columbia, MD10 participantsUniversity of Missouri-Columbia

View Study Details

About Obesity Clinical Trials in Columbia

Obesity is a complex chronic disease involving an excessive amount of body fat that increases the risk of other diseases and health problems. It affects over 650 million adults worldwide. Treatment approaches include lifestyle modifications, medications (GLP-1 agonists), and bariatric surgery.

There are currently 14 obesity clinical trials recruiting participants in Columbia, MD. These studies are seeking a combined 1,808 participants. Research is being sponsored by University of South Carolina, Russell McCulloh, MD, Veru Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Obesity Clinical Trials in Columbia — FAQ

Are there obesity clinical trials in Columbia?

Yes, there are 14 obesity clinical trials currently recruiting in Columbia, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbia research site will contact you about next steps.

Are clinical trials in Columbia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbia studies also compensate for your time and travel.

What obesity treatments are being tested?

The 14 active trials in Columbia are testing new therapies including novel drugs, biologics, and treatment approaches for obesity.

Data updated July 13, 2026 from ClinicalTrials.gov