Columbia, MISSOURI10 Active Studies

Ankylosing Spondylitis Clinical Trials in Columbia, MISSOURI

Find 10 actively recruiting ankylosing spondylitis clinical trials in Columbia, MISSOURI. Connect with local research sites and explore new treatment options.

10
Active Trials
9
Sponsors
11,224
Enrolling

Recruiting Ankylosing Spondylitis Studies in Columbia

RecruitingColumbia, MISSOURINCT07157774

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart a...

10,450 participants
Eli Lilly and Company
View Study Details
RecruitingColumbia, MISSOURINCT06706817

A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab

The main objective of this study is to evaluate treatment outcomes of tezepelumab among participants with physician-determined surgery-eligible CRSwNP, with or without asthma. Study details include: ...

180 participants
AstraZeneca
View Study Details
RecruitingColumbia, MISSOURINCT06340451

Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

This multicenter, randomized, double-blind, sham-controlled study is designed to evaluate the efficacy and safety of the iovera° system in subjects with upper extremity spasticity. A total of approxim...

132 participants
Pacira Pharmaceuticals, Inc
View Study Details
RecruitingColumbia, MISSOURINCT06196203

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

This is a Phase 2 randomized, double-blind, placebo-controlled, multicenter study evaluating the efficacy and safety of AK117 or placebo, combined with azacitidine in patients with newly diagnosed hig...

90 participants
Akeso
View Study Details
RecruitingColumbia, MISSOURINCT03843463

Escitalopram and Language Intervention for Subacute Aphasia

In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming un...

88 participants
Johns Hopkins University
View Study Details
RecruitingColumbia, MISSOURINCT06414954

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, a...

84 participants
NMD Pharma A/S
View Study Details
RecruitingColumbia, MISSOURINCT06482437

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

This Phase 2a study aims to evaluate the efficacy, safety and tolerability of NMD670 vs placebo administered twice a day (BID) for 21 days in ambulatory adult patients with Charcot-Marie-Tooth disease...

80 participants
NMD Pharma A/S
View Study Details
RecruitingColumbia, MISSOURINCT07126262

A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months

The purpose of this study is to evaluate the safety and efficacy of daily administration of vosoritide in participants with HCH aged 0 to \< 36 months over a 52-week period....

60 participants
BioMarin Pharmaceutical
View Study Details
RecruitingColumbia, MISSOURINCT05748834

Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

This clinical trial is evaluating tucatinib in combination with Doxil in participants with human epidermal growth factor 2 positive (HER2+) locally advanced or metastatic breast cancer. The main goals...

36 participants
SCRI Development Innovations, LLC
View Study Details
RecruitingColumbia, MISSOURINCT06322342

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

This Phase 2 clinical trial will study RVP-001, a new manganese-based MRI contrast agent, in people who are known to have gadolinium-enhancing central nervous system (CNS) lesions, for example brain t...

24 participants
Reveal Pharmaceuticals Inc.
View Study Details

About Ankylosing Spondylitis Clinical Trials in Columbia

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 10 ankylosing spondylitis clinical trials recruiting participants in Columbia, MISSOURI. These studies are seeking a combined 11,224 participants. Research is being sponsored by Eli Lilly and Company, AstraZeneca, Pacira Pharmaceuticals, Inc and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Columbia — FAQ

Are there ankylosing spondylitis clinical trials in Columbia?

Yes, there are 10 ankylosing spondylitis clinical trials currently recruiting in Columbia, MISSOURI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbia research site will contact you about next steps.

Are clinical trials in Columbia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbia studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 10 active trials in Columbia are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov