10 Heart Disease Clinical Trials in Columbus, OH (2026)

Q: How do I join a clinical trial in Columbus?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you.

Recruiting Heart Disease Studies in Columbus

NCT01192048Recruiting

Genetics of Congenital Heart Disease

Congenital heart disease (CHD) is the most common type of birth defect but the cause for the majority of cardiac birth defects remains unknown. Numerous epidemiologic studies have demonstrated evidenc...

Columbus, OH5,000 participantsNationwide Children's Hospital

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NCT06952933Recruiting

Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease

The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for expo...

Columbus, OH1,000 participantsDartmouth-Hitchcock Medical Center

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NCT06854458Recruiting

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the h...

Columbus, OHNA1,000 participantsBrigham and Women's Hospital

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NCT06870591Recruiting

Pivotal Study for the Cardiac Performance System (CPS)

This multi-center, observational study evaluates the accuracy of the Cardiac Performance System (CPS), a non-invasive device, for measuring hemodynamic parameters in adult patients undergoing clinical...

Columbus, OH1,000 participantsSensydia Corporation

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NCT05550324Recruiting

IPSC Repository of Pediatric Cardiovascular Disease

Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pe...

Columbus, OH300 participantsMingtao Zhao

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NCT05386173Recruiting

Effect of Fetal Aortic Valvuloplasty on Outcomes

In one of the most severe congenital heart defects, hypoplastic left heart syndrome (HLHS), the left ventricle is underdeveloped and the prognosis is worse than in most other heart defects. The underd...

Columbus, OH200 participantsQueen Silvia Children's Hospital, Gothenburg, Sweden

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NCT07380243Recruiting

Pathways to Prevention Food-is-Medicine Trial

The goal of this study is to learn whether combining healthy food access with personalized tools can help families improve heart health and make lasting lifestyle changes. The main questions the study...

Columbus, OHNA120 participantsAmrik Singh Khalsa

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NCT07114718Recruiting

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

Starlight Cardiovascular, Inc. is sponsoring a prospective, multi-center, study to evaluate safety and effectiveness of the Lifeline Ductus Arteriosus Stent System. The study device is a stent that is...

Columbus, OHNA45 participantsStarlight Cardiovascular Inc

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NCT07466745Recruiting

Autus Valve Continued Access Study (CAS)

Prospective, single-arm, multi-center, continued access study of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring surgical pulmonary valve replacement. The Au...

Columbus, OHNA36 participantsEdwards Lifesciences

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NCT07384585Recruiting

Feasibility of Light Therapy in the Pediatric Intensive Care Unit (ICU)

The goal of this clinical trial is to understand how easy or difficult it is for critically ill children (4-17 years old) to have light therapy while in the pediatric ICU. Participants will have a lig...

Columbus, OHNA30 participantsLaura Beth Kalvas

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About Heart Disease Clinical Trials in Columbus

Heart disease is the leading cause of death worldwide, encompassing conditions that affect the heart and blood vessels. Coronary artery disease, the most common type, occurs when arteries supplying the heart become narrowed or blocked. Risk factors include high blood pressure, high cholesterol, diabetes, and smoking.

There are currently 10 heart disease clinical trials recruiting participants in Columbus, OH. These studies are seeking a combined 8,731 participants. Research is being sponsored by Nationwide Children's Hospital, Dartmouth-Hitchcock Medical Center, Brigham and Women's Hospital and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Disease Clinical Trials in Columbus — FAQ

Are there heart disease clinical trials in Columbus?

Yes, there are 10 heart disease clinical trials currently recruiting in Columbus, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbus?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you about next steps.

Are clinical trials in Columbus free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbus studies also compensate for your time and travel.

What heart disease treatments are being tested?

The 10 active trials in Columbus are testing new therapies including novel drugs, biologics, and treatment approaches for heart disease.

Data updated September 2, 2026 from ClinicalTrials.gov