40 Interstitial Cystitis Clinical Trials in Columbus, OH (2026)

Q: How do I join a clinical trial in Columbus?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you.

Recruiting Interstitial Cystitis Studies in Columbus

NCT06057181Recruiting

Helix Research Network

The Helix Research Network ("HRN") is a network of academic, public, and/or private healthcare organizations that are committed to advancing medical research and improving human health through large-s...

Columbus, OH2,000,000 participantsHelix, Inc

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NCT01522183Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab....

Columbus, OH3,000 participantsAlexion Pharmaceuticals, Inc.

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NCT06094218Recruiting

Development of a Treatment Prognosis Calculator for the Prevention of Suicide

The goal of this interventional study is to develop and test a treatment prognosis calculator to identify which service members with suicidal ideation or behavior are likely to respond well to the cur...

Columbus, OHNA1,200 participantsOhio State University

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NCT06071377Recruiting

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences ...

Columbus, OH1,000 participantsNational Alliance for Sickle Cell Centers

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NCT01473784Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

This pilot clinical trial studies transoral robotic surgery (TORS) in treating patients with benign or malignant tumors of the head and neck. TORS is a less invasive type of surgery for head and neck ...

Columbus, OHNA600 participantsOhio State University Comprehensive Cancer Center

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NCT03492151Recruiting

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

The study schema is shown in Figure 4. (A) All patients referred to one of the participating academic centers for EUS evaluation of the PCL will be enrolled in the protocol if they satisfy inclusion c...

Columbus, OH500 participantsOhio State University Comprehensive Cancer Center

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NCT07122700Recruiting

Evaluation of Non-Invasive Tests for Metabolic Liver Disease

The Non-Invasive Biomarkers for Metabolic Liver Disease (NIMBLE) study is a comprehensive, multi-year collaborative effort to standardize, validate and advance the regulatory qualification of blood- a...

Columbus, OH400 participantsFoundation for the National Institutes of Health

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NCT06654882Recruiting

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

This study is an open-label, randomized, multicenter trial that incorporates a multi-arm design comparing each of 3 non-TNFi (Tumor Necrosis Factor inhibitor) medications to a second TNFi (active cont...

Columbus, OHPHASE3400 participantsDuke University

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NCT06055036Recruiting

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, gly...

Columbus, OHNA340 participantsOhio State University

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NCT07312734Recruiting

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

Sputum culture has been the best approach to detect harmful bacteria in the lungs of people with cystic fibrosis (CF). With the widespread use of new CF therapies (like Trikafta and Alyftrak), it is m...

Columbus, OH300 participantsChris Goss

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NCT07335497Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) ...

Columbus, OHPHASE1290 participantsCrescent Biopharma, Inc.

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NCT02860364Recruiting

Comparing Hypothermic Temperatures During Hemiarch Surgery

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral...

Columbus, OHNA282 participantsOttawa Heart Institute Research Corporation

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NCT07214311Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a ...

Columbus, OHPHASE2240 participantsPeptilogics

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NCT06476886Recruiting

Intensive Crisis Intervention

The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric car...

Columbus, OHNA213 participantsJennifer Hughes

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NCT06314672Recruiting

Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

This clinical trial tests the impact of the The Ohio State University Connecting Underrepresented Populations to Clinical Trials (CUSP2CT) project on clinical trial referrals and enrollment in racial/...

Columbus, OHNA208 participantsOhio State University Comprehensive Cancer Center

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NCT06118554Recruiting

3D Printing to Improve Nasal Irrigation Outcome

Three-dimensional (3D) printing has been an emerging technology with uses in a wide array of fields. This research aims to use 3D printing as a tool to provide personalized education to maximize treat...

Columbus, OHNA200 participantsOhio State University

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NCT05178472Recruiting

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

This clinical trial studies the side effects of stereotactic radiosurgery and how well it works with or without vertebroplasty, separation surgery, or immunotherapy in patients with cancer that is rad...

Columbus, OHNA200 participantsOhio State University Comprehensive Cancer Center

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NCT07027995Recruiting

Food and Fitness With Medicine (FFWM)

Food and Fitness with Medicine (FFWM) is a 24-week randomized controlled trial (RCT) enrolling 200 post-menopausal women (PMW) with stage 2 cardio-kidney metabolic (CKM) syndrome and type-2 diabetes (...

Columbus, OHNA200 participantsOhio State University

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NCT02387255Recruiting

Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive a...

Columbus, OH165 participantsOhio State University

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NCT07103018Recruiting

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

Study K36-MCRPC-001 is the first in human clinical trial testing KTX-2001 alone and with darolutamide in men with metastatic castration-resistant prostate cancer. The study aims to assess whether the ...

Columbus, OHPHASE1144 participantsK36 Therapeutics, Inc.

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NCT06576271Recruiting

A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants

This study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of GSK4527363 in healthy participants (Part A), participants with active SLE (Part B), healthy pa...

Columbus, OHPHASE1142 participantsGlaxoSmithKline

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NCT07080242Recruiting

Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

The objective of this study is to evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of BL-M14D1 in Subjects with locally Advanced or Metastatic Small Cell Lung Cancer and Other Neuroen...

Columbus, OHPHASE1120 participantsSystImmune Inc.

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NCT06710756Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Phase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation Protein (FAP)-positive....

Columbus, OHPHASE1112 participantsPerspective Therapeutics

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NCT06447025Recruiting

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

An open label study designed to evaluate the safety, PK, PD, and clinical effects of long-term daily administration of CTI-1601 enrolling adolescent and adult patients with FRDA who have participated ...

Columbus, OHPHASE285 participantsLarimar Therapeutics, Inc.

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NCT06233318Recruiting

Sternotomy PIFB Block in Open Heart Surgery

The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia \[...

Columbus, OHNA84 participantsOhio State University

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NCT03711890Recruiting

Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer

This trial studies how well ultra-high resolution optical coherence tomography works in detecting micrometer sized early stage pancreatic cancer in participants with pancreatic cancer. Ultra-high reso...

Columbus, OHNA75 participantsOhio State University Comprehensive Cancer Center

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NCT06757647Recruiting

Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

This phase II trial tests how well acalabrutinib works in treating patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and evaluates how treatment with acalabrutinib affe...

Columbus, OHPHASE261 participantsSeema Bhat

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NCT06582615Recruiting

Food for Thought - A Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer

The goal of this randomized clinical trial is to learn if a healthy eating pattern called the MIND eating plan can reduce cancer-related cognitive impairment (commonly called "chemobrain") and other s...

Columbus, OHNA60 participantsOhio State University Comprehensive Cancer Center

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NCT05695430Recruiting

Brief Cognitive Behavioral Therapy for People With Physical Disabilities

The purpose of this study is to examine the effectiveness of a psychotherapy (non-medication) treatment, Brief Cognitive Behavioral Therapy for Suicide Prevention, in reducing suicide ideation and att...

Columbus, OHNA60 participantsOhio State University

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NCT07169370Recruiting

SPIRIT Club Chronic Brain Injury Exercise Platform

Many physical fitness centers and online exercise programs are not designed to support people with intellectual and developmental disabilities. To address this, the investigators are collaborating wit...

Columbus, OHNA60 participantsOhio State University

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NCT05422794Recruiting

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

This phase Ib trial tests the safety and tolerability of ZEN003694 in combination with an immunotherapy drug called pembrolizumab and the usual chemotherapy approach with nab-paclitaxel for the treatm...

Columbus, OHPHASE157 participantsNational Cancer Institute (NCI)

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NCT04588025Recruiting

Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

The goal of this study is to investigate whether the therapeutic response of pancreatic tumors can be accurately assessed using quantitative DCE-MRI, when the inter/intra-scanner variability is reduce...

Columbus, OHNA55 participantsOhio State University

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NCT06082947Recruiting

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

This is a study utilizing the Magnetic-activated cell sorting (CliniMACS®) Alpha-Beta T-cell (αβT)/Cluster of Differentiation 19 (CD19), also called B lymphocyte antigen CD19 depletion device for Chil...

Columbus, OHNA50 participantsNationwide Children's Hospital

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NCT05417308Recruiting

Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

This early phase I trial studies the possible benefits and/or side effects of topical or oral minoxidil in treating endocrine therapy-induced hair loss (alopecia) in patients with stage I-IV breast ca...

Columbus, OHEARLY_PHASE150 participantsOhio State University Comprehensive Cancer Center

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NCT06609317Recruiting

Postpartum pElvic Assisted Recovery With Leva

The goal of this prospective cohort study is to evaluate the feasibility of postpartum pelvic floor muscle training using an FDA-cleared digital therapeutic motion-based device. In addition to assess...

Columbus, OHNA25 participantsUniversity of South Florida

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NCT06325644Recruiting

Well-Formulated Ketogenic Diet Polycystic Kidney Disease

This is a prospective study to determine ketogenic diet effect on htTKV, GFR, microalbuminuria. This is a single-center study of 20 patients with ADPKD and deemed high risk for progression to ESRD. Th...

Columbus, OHNA20 participantsOhio State University

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NCT05913908Recruiting

EFS of the DUO System for Tricuspid Regurgitation

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcatheter Tricuspid Coaptation Valve System (...

Columbus, OHNA15 participantsCroiValve Limited

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NCT07106021Recruiting

A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure....

Columbus, OHPHASE112 participantsKenai Therapeutics

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NCT07180355Recruiting

A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

This is a phase 1b, first in-human, open-label, dose-finding study investigating the safety and tolerability of SGT-212 in participants with Friedreich's ataxia (FA). It will be delivered via dual int...

Columbus, OHPHASE110 participantsSolid Biosciences Inc.

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NCT06192576Recruiting

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

US, multicenter, cohort, open label observational study with primary data collection. Ancillary protocol-specified procedures to address the study objectives (eg, assessment of ADA) may be considered ...

Columbus, OH10 participantsSanofi

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About Interstitial Cystitis Clinical Trials in Columbus

Interstitial cystitis/bladder pain syndrome is a chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain. It primarily affects women and can significantly impact quality of life. Treatment includes dietary changes, bladder instillations, oral medications, and neuromodulation.

There are currently 40 interstitial cystitis clinical trials recruiting participants in Columbus, OH. These studies are seeking a combined 2,011,045 participants. Research is being sponsored by Helix, Inc, Alexion Pharmaceuticals, Inc., Ohio State University and 22 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Interstitial Cystitis Clinical Trials in Columbus — FAQ

Are there interstitial cystitis clinical trials in Columbus?

Yes, there are 40 interstitial cystitis clinical trials currently recruiting in Columbus, OH. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Columbus?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Columbus research site will contact you about next steps.

Are clinical trials in Columbus free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Columbus studies also compensate for your time and travel.

What interstitial cystitis treatments are being tested?

The 40 active trials in Columbus are testing new therapies including novel drugs, biologics, and treatment approaches for interstitial cystitis.

Data updated July 18, 2026 from ClinicalTrials.gov