Costa Mesa, CALIFORNIA6 Active Studies

Alzheimers Disease Clinical Trials in Costa Mesa, CALIFORNIA

Find 6 actively recruiting alzheimers disease clinical trials in Costa Mesa, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
3,139
Enrolling

Recruiting Alzheimers Disease Studies in Costa Mesa

RecruitingCosta Mesa, CALIFORNIANCT06159673

ACP-204 in Adults With Alzheimer's Disease Psychosis

This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies in patients with ADP * Substudy 1 (Phase 2) will e...

1,074 participants
ACADIA Pharmaceuticals Inc.
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RecruitingCosta Mesa, CALIFORNIANCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT and KarXT + KarX-EC in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

This is a Phase 3 global, multicenter, 52-week, open-label extension (OLE) rollover study for subjects completing study CN012-0026, CN012-0027, CN012-0056 or CN012-0034. Subjects (randomized or non-ra...

800 participants
Karuna Therapeutics
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RecruitingCosta Mesa, CALIFORNIANCT05397639

Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, tolerability, and pharmacokinetics of masupirdine compared to placebo for the treatment of agitation in participants with dementia of the...

375 participants
Suven Life Sciences Limited
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RecruitingCosta Mesa, CALIFORNIANCT06540833

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo in the trea...

370 participants
Intra-Cellular Therapies, Inc.
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RecruitingCosta Mesa, CALIFORNIANCT06651567

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

This is a multicenter, randomized, double-blind, placebo-controlled, flexible-dose study of the efficacy, safety, and tolerability of ITI-1284 in patients with agitation associated with Alzheimer's de...

320 participants
Intra-Cellular Therapies, Inc.
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RecruitingCosta Mesa, CALIFORNIANCT04838301

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

A phase 2, double-blind, randomized, placebo-controlled clinical trial to evaluate the safety and efficacy of Allopregnanolone as a regenerative therapeutic for Alzheimer's disease....

200 participants
University of Arizona
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About Alzheimers Disease Clinical Trials in Costa Mesa

Alzheimer's disease is a progressive brain disorder that destroys memory, thinking skills, and the ability to carry out daily tasks. It is the most common cause of dementia, affecting over 6.7 million Americans age 65 and older. The disease is characterized by amyloid-beta plaques and tau tangles in the brain. Recent FDA approvals of anti-amyloid antibodies like lecanemab (Leqembi) and donanemab have opened a new era of disease-modifying treatments. Clinical trials are now exploring next-generation amyloid-clearing therapies, tau-targeting treatments, anti-inflammatory approaches, and combination strategies. Early-stage patients with mild cognitive impairment or early Alzheimer's are frequently sought for enrollment, and many trials now use blood-based biomarkers for screening.

There are currently 6 alzheimers disease clinical trials recruiting participants in Costa Mesa, CALIFORNIA. These studies are seeking a combined 3,139 participants. Research is being sponsored by ACADIA Pharmaceuticals Inc., Karuna Therapeutics, Suven Life Sciences Limited and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Alzheimers Disease Clinical Trials in Costa Mesa — FAQ

Are there alzheimers disease clinical trials in Costa Mesa?

Yes, there are 6 alzheimers disease clinical trials currently recruiting in Costa Mesa, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Costa Mesa?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Costa Mesa research site will contact you about next steps.

Are clinical trials in Costa Mesa free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Costa Mesa studies also compensate for your time and travel.

What alzheimers disease treatments are being tested?

The 6 active trials in Costa Mesa are testing new therapies including novel drugs, biologics, and treatment approaches for alzheimers disease.

Data updated March 2, 2026 from ClinicalTrials.gov