16 Heart Failure Clinical Trials in Dallas, PA (2026)

Q: How do I join a clinical trial in Dallas?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Dallas research site will contact you.

Recruiting Heart Failure Studies in Dallas

NCT02693509Recruiting

Get With The Guidelines-Heart Failure Registry

Get With The Guidelines-Heart Failure is designed to improve the quality of care in patients hospitalized with heart failure. The program aims to help ensure that eligible patients are initiated on gu...

Dallas, PA128,026 participantsAmerican Heart Association

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NCT06593314Recruiting

Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes

A pragmatic electronic health record (EHR) based randomized controlled trial to evaluate the utility of providing Ultromics EchoGo analysis results and recommendations for HF risk prevention therapies...

Dallas, PA800 participantsUniversity of Texas Southwestern Medical Center

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NCT06349941Recruiting

Home-based Cardiac Rehabilitation in Heart Failure

This study evaluates a mobile health (mHealth) home-based cardiac rehabilitation program for patients with heart failure. We will stratify randomization between rural and urban populations, with the g...

Dallas, PA332 participantsUniversity of Texas Southwestern Medical Center

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NCT06939751Recruiting

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circulating miRs (associated with drug doses and...

Dallas, PA250 participantsInova Health Care Services

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NCT04982419Recruiting

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, func...

Dallas, PA240 participantsVA Office of Research and Development

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NCT07223242Recruiting

Tailored Exercise Training Study Among Adults With HFpEF

Heart failure with preserved ejection fraction (HFpEF) is associated with a high morbidity and mortality burden. There are limited pharmacological options available for the treatment of HFpEF. Exercis...

Dallas, PA120 participantsUniversity of Texas Southwestern Medical Center

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NCT06961929Recruiting

IEEM-Heat and Heart Failure

We will test the hypothesis that increasing skin wetness, and thus evaporative cooling, will attenuate the increase in core body temperature and accompanying cardiac stress during heat wave conditions...

Dallas, PA88 participantsUniversity of Texas Southwestern Medical Center

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NCT05723679Recruiting

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

The overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patient...

Dallas, PA78 participantsUniversity of Texas Southwestern Medical Center

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NCT06130059Recruiting

Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

The purpose of this research study is to determine the effectiveness of low dose colchicine (LoDoCo) on measures of exercise capacity, physical function, frailty, and quality of life, among patients w...

Dallas, PA60 participantsUniversity of Texas Southwestern Medical Center

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NCT04703842Recruiting

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which ...

Dallas, PA57 participantsSardocor Corp.

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NCT06350695Recruiting

The ROle of Compression StocKings in Heart Failure Patients

Congestive heart failure (CHF) occurs when the heart is weak and not able to effectively pump blood to the body. One of the common manifestations of CHF is fluid overload and swelling of the legs. Diu...

Dallas, PA50 participantsUniversity of Maryland, Baltimore

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NCT06080074Recruiting

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

There are two primary goals of this multicenter clinical trial that combines an FDA device trial and a phase II drug trial in the same study cohort. These two goals are to: 1. To evaluate the safety ...

Dallas, PA50 participantsStanford University

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NCT04656080Recruiting

Cardiopulmonary Stress Testing (CPET) AlloSure Study

1. Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ. (The imp...

Dallas, PA27 participantsBaylor Research Institute

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NCT03383419Recruiting

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

This phase II, multi-center, open-label study will evaluate the safety and efficacy of utilizing HCV-positive donors for heart transplant in HCV-negative recipients treated with sofosbuvir 400 mg / ve...

Dallas, PA15 participantsBaylor Research Institute

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NCT06560762Recruiting

Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

A Phase 1, Open label, Multiple Ascending Dose Study to Assess Safety and Tolerability of STM-01 in Participants with Heart Failure with Preserved Ejection Fraction (HFpEF)...

Dallas, PA12 participantsSecretome Therapeutics

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NCT06061549Recruiting

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction

The goal of this clinical trial is to test an experimental gene therapy in participants with heart failure with preserved ejection fraction, also known as diastolic heart failure. The main questions i...

Dallas, PA10 participantsSardocor Corp.

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About Heart Failure Clinical Trials in Dallas

Heart failure is a chronic condition where the heart cannot pump blood efficiently to meet the body's needs. It affects millions of people worldwide and can result from various heart conditions. Treatment includes medications, lifestyle changes, devices, and in severe cases, heart transplant.

There are currently 16 heart failure clinical trials recruiting participants in Dallas, PA. These studies are seeking a combined 130,215 participants. Research is being sponsored by American Heart Association, University of Texas Southwestern Medical Center, Inova Health Care Services and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Failure Clinical Trials in Dallas — FAQ

Are there heart failure clinical trials in Dallas?

Yes, there are 16 heart failure clinical trials currently recruiting in Dallas, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Dallas?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Dallas research site will contact you about next steps.

Are clinical trials in Dallas free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Dallas studies also compensate for your time and travel.

What heart failure treatments are being tested?

The 16 active trials in Dallas are testing new therapies including novel drugs, biologics, and treatment approaches for heart failure.

Data updated July 13, 2026 from ClinicalTrials.gov