Denver, COLORADO17 Active Studies

Advanced Solid Tumors Clinical Trials in Denver, COLORADO

Find 17 actively recruiting advanced solid tumors clinical trials in Denver, COLORADO. Connect with local research sites and explore new treatment options.

17
Active Trials
16
Sponsors
4,418
Enrolling

Recruiting Advanced Solid Tumors Studies in Denver

RecruitingDenver, COLORADONCT04657068

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

This clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors. The main goals of this study are to: * Find the recommended dose of ART0380 that can ...

597 participants
Artios Pharma Ltd
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RecruitingDenver, COLORADONCT05410145

A Study of D3S 001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation

This is a first-in-human (FIH), multicenter, open-label, dose-escalation, and dose-expansion Phase 1/2 clinical trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and prel...

442 participants
D3 Bio (Wuxi) Co., Ltd
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RecruitingDenver, COLORADONCT07038343

Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

This study, the first clinical trial of AVZO-1418, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-1418 when admi...

430 participants
Avenzo Therapeutics, Inc.
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RecruitingDenver, COLORADONCT06914128

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

The study treatment, BAY 3713372, is under development to treat MTAP (methylthioadenosine phosphorylase)-deleted solid tumors. It is thought to work by blocking the protein arginine N-methyltransferas...

370 participants
Bayer
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RecruitingDenver, COLORADONCT05592626

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with ad...

365 participants
Marengo Therapeutics, Inc.
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RecruitingDenver, COLORADONCT05669430

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care....

365 participants
GV20 Therapeutics
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RecruitingDenver, COLORADONCT06265727

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

The goal of this clinical trial is to define a safe and effective dose of CRB-701 for participants with solid tumors that are expressing a protein called nectin-4. The main questions it aims to answe...

348 participants
Corbus Pharmaceuticals Inc.
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RecruitingDenver, COLORADONCT04145622

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

This is a single group study of participants with advanced solid tumors who have not been cured by other treatments. It is the first time the drug will be used in humans, and will be in two parts. Th...

250 participants
Daiichi Sankyo
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RecruitingDenver, COLORADONCT04585750

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tum...

230 participants
PMV Pharmaceuticals, Inc
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RecruitingDenver, COLORADONCT04219254

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors (KEYNOTE-A04)

Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1...

197 participants
BioInvent International AB
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RecruitingDenver, COLORADONCT06603844

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

The purpose of this study is to determine the safety, blood concentrations and treatment effect of CRB-601 in combination with immunotherapy in patients who have advanced solid tumors (cancer) and hav...

156 participants
Corbus Pharmaceuticals Inc.
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RecruitingDenver, COLORADONCT06386146

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

This study is to evaluate the efficacy and safety of JAB-30355 in adult participants with advanced solid tumors harboring TP53 Y220C mutation....

144 participants
Jacobio Pharmaceuticals Co., Ltd.
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RecruitingDenver, COLORADONCT06287463

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

This is a multicenter, Phase 1/2 clinical trial to evaluate DCC-3084 alone or in combination with other cancer therapies in participants with advanced cancers. Module A will enroll participants with a...

140 participants
Deciphera Pharmaceuticals, LLC
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RecruitingDenver, COLORADONCT05887492

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

The goal of this interventional clinical trial is to learn about TNG260, a CoREST inhibitor, in combination with pembrolizumab in patients with advanced solid tumors with a known STK11 mutation. The ...

126 participants
Tango Therapeutics, Inc.
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RecruitingDenver, COLORADONCT06239194

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors....

115 participants
ModeX Therapeutics, An OPKO Health Company
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RecruitingDenver, COLORADONCT06710847

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic characteristics that can make them more aggressive an...

73 participants
GlaxoSmithKline
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RecruitingDenver, COLORADONCT06253130

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

This study will evaluate the preliminary efficacy of IMP1734 in patients with recurrent advanced/metastatic breast cancer, ovarian cancer and metastatic castrate resistant prostate cancer (mCRPC) with...

70 participants
Eikon Therapeutics
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About Advanced Solid Tumors Clinical Trials in Denver

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 17 advanced solid tumors clinical trials recruiting participants in Denver, COLORADO. These studies are seeking a combined 4,418 participants. Research is being sponsored by Artios Pharma Ltd, D3 Bio (Wuxi) Co., Ltd, Avenzo Therapeutics, Inc. and 13 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Denver — FAQ

Are there advanced solid tumors clinical trials in Denver?

Yes, there are 17 advanced solid tumors clinical trials currently recruiting in Denver, COLORADO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Denver?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Denver research site will contact you about next steps.

Are clinical trials in Denver free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Denver studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 17 active trials in Denver are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated March 2, 2026 from ClinicalTrials.gov