Detroit, MICHIGAN11 Active Studies

Pulmonary Hypertension Clinical Trials in Detroit, MICHIGAN

Find 11 actively recruiting pulmonary hypertension clinical trials in Detroit, MICHIGAN. Connect with local research sites and explore new treatment options.

11
Active Trials
10
Sponsors
2,555
Enrolling

Recruiting Pulmonary Hypertension Studies in Detroit

RecruitingDetroit, MICHIGANNCT06644781

A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)

This study is designed to assess the efficacy and safety of ifinatamab deruxtecan (I-DXd) in patients with unresectable advanced or metastatic esophageal squamous cell carcinoma (ESCC) who have experi...

510 participants
Daiichi Sankyo
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RecruitingDetroit, MICHIGANNCT06091254

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin...

478 participants
Regeneron Pharmaceuticals
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RecruitingDetroit, MICHIGANNCT06356311

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

This study will compare how safe and effective sacituzumab tirumotecan is versus the treatment of physician's choice (TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The...

450 participants
Merck Sharp & Dohme LLC
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RecruitingDetroit, MICHIGANNCT06508658

A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). This study will assess how safe and effective epcoritamab plus lena...

360 participants
Genmab
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RecruitingDetroit, MICHIGANNCT05005975

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

To evaluate the long-term safety and tolerability of oral dersimelagon....

301 participants
Mitsubishi Tanabe Pharma America Inc.
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RecruitingDetroit, MICHIGANNCT06910358

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

The goal of this clinical trial is to learn if bitopertin works and is safe to treat EPP or XLP in participants 12 years or older. The main questions it aims to answer are: * Whether bitopertin incre...

150 participants
Disc Medicine, Inc
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RecruitingDetroit, MICHIGANNCT05721222

Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001)

Brief Summary: This study will test the safety, including side effects, and determine the characteristics of a drug called GEN1160 (PRO1160) in participants with solid tumors and blood cancers. Part...

110 participants
Genmab
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RecruitingDetroit, MICHIGANNCT05952024

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBC...

80 participants
AstraZeneca
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RecruitingDetroit, MICHIGANNCT04895436

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess retreatment with venetoclax-obinutuzumab (VenG) in participants previousl...

75 participants
AbbVie
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RecruitingDetroit, MICHIGANNCT05852717

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

Subjects with relapsed large cell lymphoma will receive 3 cycles of combination therapy consisting of GDP and epcoritamab. Each cycle will last 21 days. GDP consists of gemcitabine 1000 mg/m2 IV on Da...

32 participants
Dipenkumar Modi
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RecruitingDetroit, MICHIGANNCT05723055

Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

The goal of this clinical trial is to study the combination of nivolumab and axatilimab in patients with relapsed/refractory classical Hodgkin Lymphoma. This study will mainly look at if the combinati...

9 participants
University of Utah
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About Pulmonary Hypertension Clinical Trials in Detroit

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 11 pulmonary hypertension clinical trials recruiting participants in Detroit, MICHIGAN. These studies are seeking a combined 2,555 participants. Research is being sponsored by Daiichi Sankyo, Regeneron Pharmaceuticals, Merck Sharp & Dohme LLC and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Detroit — FAQ

Are there pulmonary hypertension clinical trials in Detroit?

Yes, there are 11 pulmonary hypertension clinical trials currently recruiting in Detroit, MICHIGAN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Detroit?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Detroit research site will contact you about next steps.

Are clinical trials in Detroit free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Detroit studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 11 active trials in Detroit are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov