Duarte, CALIFORNIA16 Active Studies

Breast Cancer Clinical Trials in Duarte, CALIFORNIA

Find 16 actively recruiting breast cancer clinical trials in Duarte, CALIFORNIA. Connect with local research sites and explore new treatment options.

16
Active Trials
9
Sponsors
15,869
Enrolling

Recruiting Breast Cancer Studies in Duarte

RecruitingDuarte, CALIFORNIANCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high ...

5,500 participants
AstraZeneca
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RecruitingDuarte, CALIFORNIANCT01042379

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learn...

5,000 participants
QuantumLeap Healthcare Collaborative
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RecruitingDuarte, CALIFORNIANCT03488693

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers w...

2,140 participants
Canadian Cancer Trials Group
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RecruitingDuarte, CALIFORNIANCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with investigator's choice chemot...

625 participants
AstraZeneca
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RecruitingDuarte, CALIFORNIANCT03424005

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

This is an umbrella study evaluating the efficacy and safety of multiple treatment combinations in participants with metastatic or inoperable locally advanced breast cancer. The study will be perform...

580 participants
Hoffmann-La Roche
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RecruitingDuarte, CALIFORNIANCT04482309

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

This is an open-label, multi-center, multi-cohort, Phase 2 study to evaluate the efficacy and safety of trastuzumab deruxtecan (T-DXd) for the treatment of selected HER2-expressing tumors. This study...

468 participants
AstraZeneca
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RecruitingDuarte, CALIFORNIANCT05563220

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

This is a multicenter, Phase 1b/2 trial in participants with estrogen receptor positive/human epidermal growth factor receptor 2 negative (ER+/HER2-) advanced/metastatic breast cancer. The phase 1b pa...

435 participants
Stemline Therapeutics, Inc.
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RecruitingDuarte, CALIFORNIANCT04802759

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

This is a Phase Ib/II, open-label, multicenter, randomized umbrella study in participants with breast cancer. The study is designed with the flexibility to open new treatment arms as new treatments be...

316 participants
Hoffmann-La Roche
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RecruitingDuarte, CALIFORNIANCT06763328

Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

This phase III trial evaluates how often women develop insulin resistance and type-2 diabetes and compares metformin with usual care to usual care alone in treating insulin resistance in women with st...

200 participants
City of Hope Medical Center
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RecruitingDuarte, CALIFORNIANCT06042569

Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

This phase II trial tests how well dose-reduced docetaxel combined with cyclophosphamide works in treating older women with early stage (stage I-III) HER2 negative breast cancer vulnerable to toxicity...

174 participants
City of Hope Medical Center
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RecruitingDuarte, CALIFORNIANCT06764940

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

This study is a multicenter, two-stage clinical trial to evaluate the efficacy and safety of utidelone in combination with capecitabine in patients with HER2-negative breast cancer with brain metastas...

120 participants
Biostar Pharma, Inc.
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RecruitingDuarte, CALIFORNIANCT05595499

Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors

This phase II trial tests whether fisetin works to improve physical function in women who have received chemotherapy for stage I-III breast cancer treatment. Fisetin is a naturally occurring substance...

88 participants
Jonsson Comprehensive Cancer Center
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RecruitingDuarte, CALIFORNIANCT06954831

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

This clinical trial tests how well ultra-hypofractionated (UF) whole breast irradiation (WBI) with lumpectomy cavity boost (CB) works in treating patients with stage I-III breast cancer. Breast conser...

82 participants
City of Hope Medical Center
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RecruitingDuarte, CALIFORNIANCT05941520

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

This phase IIA trial compares the effect of acolbifene versus low dose tamoxifen in preventing breast cancer in premenopausal women at high risk for developing breast cancer. The usual approach for pa...

80 participants
National Cancer Institute (NCI)
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RecruitingDuarte, CALIFORNIANCT04305834

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

This phase IIa trial studies the side effects of abemaciclib monotherapy in treating patients age 70 years and older with hormone receptor positive, HER2 negative breast cancer that has spread to othe...

43 participants
City of Hope Medical Center
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RecruitingDuarte, CALIFORNIANCT06260033

Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

This phase II trial tests how well stereotactic body radiation therapy (SBRT) works in treating patients with estrogen receptor positive (ER +) breast cancer that has spread from where it first starte...

18 participants
City of Hope Medical Center
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About Breast Cancer Clinical Trials in Duarte

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 16 breast cancer clinical trials recruiting participants in Duarte, CALIFORNIA. These studies are seeking a combined 15,869 participants. Research is being sponsored by AstraZeneca, QuantumLeap Healthcare Collaborative, Canadian Cancer Trials Group and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Duarte — FAQ

Are there breast cancer clinical trials in Duarte?

Yes, there are 16 breast cancer clinical trials currently recruiting in Duarte, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Duarte?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Duarte research site will contact you about next steps.

Are clinical trials in Duarte free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Duarte studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 16 active trials in Duarte are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov