26 Heart Attack Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Heart Attack Studies in Durham

NCT06150781Recruiting

Aimovig Pregnancy Exposure Registry

The primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of w...

Durham, NC2,842 participantsAmgen

View Study Details

NCT04669548Recruiting

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular ...

Durham, NC2,500 participantsPotrero Medical

View Study Details

NCT04194138Recruiting

Complex Adult Deformity Surgery (CADS)

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative c...

Durham, NC1,500 participantsInternational Spine Study Group Foundation

View Study Details

NCT06080698Recruiting

Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

The Gram-negative bloodstream infection Oral Antibiotic Therapy trial (The GOAT Trial) is a multi-center, randomized clinical trial that hypothesizes that early transition to oral antibiotic therapy f...

Durham, NCNA1,030 participantsJohns Hopkins University

View Study Details

NCT00512694Recruiting

Duke Lupus Registry

Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger w...

Durham, NC1,000 participantsDuke University

View Study Details

NCT04761120Recruiting

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

ARB-PMCF is a multicenter, observational study of the safety and performance of Abbott annuloplasty devices used in surgical repair of mitral and tricuspid valve regurgitation. The devices included in...

Durham, NC550 participantsAbbott Medical Devices

View Study Details

NCT06458075Recruiting

Intervention to Improve Communication and Medication Adherence in Lupus

CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). The purpose of this study is to optimize the cult...

Durham, NCNA480 participantsDuke University

View Study Details

NCT06568601Recruiting

Pharmacogenomic Informed Statin Prescribing

Statins are the most cost-effective medications to lower cholesterol and cardiovascular disease (CVD) risk. However, many patients at high-risk for CVD do not accept or adhere to statins. This gap in ...

Durham, NCNA410 participantsVA Office of Research and Development

View Study Details

NCT06351631Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bome...

Durham, NCPHASE3400 participantsMerck Sharp & Dohme LLC

View Study Details

NCT06601933Recruiting

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transition to dementia. Cognitive training represe...

Durham, NCPHASE2240 participantsColumbia University

View Study Details

NCT04888104Recruiting

Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients...

Durham, NC225 participantsInternational Spine Study Group Foundation

View Study Details

NCT06472128Recruiting

Novel Digital Application for Patients With Acute Leukemia

This research study is evaluating to examine the efficacy of a novel a self-administered digital application (DREAMLAND) for improving patients' long-term quality of life and psychological outcomes fo...

Durham, NCNA200 participantsMassachusetts General Hospital

View Study Details

NCT06065202Recruiting

Personalized Nutrition to Improve Recovery in Trauma

The purpose of this study is to determine if a particular method of providing nutrition improves the outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery followin...

Durham, NCPHASE2150 participantsDuke University

View Study Details

NCT05362773Recruiting

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

CP-MGD024-01 is a Phase 1, open-label, multi-center study of MGD024 as a single agent in participants with select blood cancers that have not responded to treatment with standard therapies or who have...

Durham, NCPHASE1130 participantsMacroGenics

View Study Details

NCT06520098Recruiting

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

People who have chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) are often treated with ibrutinib, acalabrutinib, or zanubrutinib. These are pills that are taken by mouth. This t...

Durham, NCPHASE2100 participantsVA Office of Research and Development

View Study Details

NCT04159103Recruiting

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

This 3-part, Phase 1/2 study is designed to characterize the safety, tolerability, and pharmacological activity (as assessed by biomarker measurements) and to determine the selected dose of mRNA-3927 ...

Durham, NCPHASE177 participantsModernaTX, Inc.

View Study Details

NCT06222450Recruiting

Vestibular Rehabilitation App for Adults With Dizziness Related to mTBI

The goal of this clinical trial is to compare outcomes for standard vestibular rehabilitation home program to a digital vestibular rehabilitation home program in adults with dizziness related to mild ...

Durham, NCNA68 participantsMountain Home Research & Education Corporation

View Study Details

NCT07085104Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) ...

Durham, NCPHASE166 participantsAllogene Therapeutics

View Study Details

NCT06985147Recruiting

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics...

Durham, NCPHASE260 participantsDisc Medicine, Inc

View Study Details

NCT05546580Recruiting

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat ...

Durham, NCPHASE150 participantsOryzon Genomics S.A.

View Study Details

NCT06778278Recruiting

Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans

The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life. It is hypothesize...

Durham, NCNA40 participantsRTI International

View Study Details

NCT05766839Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

A study to evaluate the pharmacodynamic effects, safety, and tolerability of patiromer in children under 12 years of age with hyperkalaemia...

Durham, NCPHASE232 participantsVifor Pharma, Inc.

View Study Details

NCT07166926Recruiting

Pediatrics Mobile CT

A special kind of CT scanner that can move around (called a mobile CT) is already approved by the FDA to take pictures of adult and pediatric heads. This study wants to see if the same machine can saf...

Durham, NCNA25 participantsDuke University

View Study Details

NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Durham, NCPHASE120 participantsAdaptimmune

View Study Details

NCT04704323Recruiting

CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia

Introduction of immuno-chemotherapy in the treatment options of CLL and SLL changed the treatment paradigm of these diseases. Presently, first-line therapies for CLL/SLL include targeted therapies (e....

Durham, NCPHASE118 participantsCatapult Therapeutics

View Study Details

NCT06328777Recruiting

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

RESET-SSc: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T cell therapy, in Subjects with Systemic Sclerosis...

Durham, NCPHASE112 participantsCabaletta Bio

View Study Details

About Heart Attack Clinical Trials in Durham

A heart attack (myocardial infarction) occurs when blood flow to part of the heart muscle is blocked, usually by a blood clot. It is a medical emergency requiring immediate treatment. Long-term management includes medications, lifestyle changes, and cardiac rehabilitation.

There are currently 26 heart attack clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 12,225 participants. Research is being sponsored by Amgen, Potrero Medical, International Spine Study Group Foundation and 18 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Attack Clinical Trials in Durham — FAQ

Are there heart attack clinical trials in Durham?

Yes, there are 26 heart attack clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What heart attack treatments are being tested?

The 26 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for heart attack.

Data updated July 18, 2026 from ClinicalTrials.gov