Durham, NC7 Active Studies

Pulmonary Hypertension Clinical Trials in Durham, NC

Find 7 actively recruiting pulmonary hypertension clinical trials in Durham, NC. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
608
Enrolling

Recruiting Pulmonary Hypertension Studies in Durham

RecruitingDurham, NCNCT07038200

A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous AOC 1020 for the Treatment of Facioscapulohumeral Muscular Dystrophy (FSHD)...

200 participants
Avidity Biosciences, Inc.
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RecruitingDurham, NCNCT06635850

A Study of Mosliciguat in PH-ILD

This is a Phase 2, randomized, double-blind, placebo-controlled, multi-center clinical study to evaluate the safety and efficacy of inhaled mosliciguat in participants with pulmonary hypertension asso...

120 participants
Pulmovant, Inc.
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RecruitingDurham, NCNCT04858256

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

The main purpose of this study is to determine the effectiveness of the study drug pacritinib in people with relapsed or refractory lymphoproliferative disorders....

100 participants
University of Michigan Rogel Cancer Center
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RecruitingDurham, NCNCT05563766

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

Esophageal cancer, which has a low 5-year overall survival rate (\<20%) is increasing in incidence. Previous studies have shown that Hedgehog, AKT, and angiogenic signaling pathways are activated in a...

78 participants
VA Office of Research and Development
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RecruitingDurham, NCNCT04747236

Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL

The purpose of this study is to find out whether the combination treatment of romidepsin and oral azacytidine is safe and effective in patients with Peripheral T-Cell Lymphoma (PTCL). This study will ...

50 participants
University of Virginia
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RecruitingDurham, NCNCT05233397

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

ACTEMRA (tocilizumab) is an IL-6 receptor antagonist used for the treatment of adult Rheumatoid Arthritis as well as Polyarticular (PJIA) and Systemic (SJIA) Juvenile Idiopathic Arthritis. In this Pha...

38 participants
Nationwide Children's Hospital
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RecruitingDurham, NCNCT05671757

Daratumumab in Primary Antiphospholipid Syndrome

The purpose of this study is to see if the study medication, daratumumab, is safe to treat individuals with Anti-Phospholipid Syndrome (APS). Three daratumumab dosing cohorts are planned with up to s...

22 participants
National Institute of Allergy and Infectious Diseases (NIAID)
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About Pulmonary Hypertension Clinical Trials in Durham

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 7 pulmonary hypertension clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 608 participants. Research is being sponsored by Avidity Biosciences, Inc., Pulmovant, Inc., University of Michigan Rogel Cancer Center and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Durham — FAQ

Are there pulmonary hypertension clinical trials in Durham?

Yes, there are 7 pulmonary hypertension clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 7 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov