Durham, NORTH%20CAROLINA7 Active Studies

Breast Cancer Clinical Trials in Durham, NORTH%20CAROLINA

Find 7 actively recruiting breast cancer clinical trials in Durham, NORTH%20CAROLINA. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
949
Enrolling

Recruiting Breast Cancer Studies in Durham

RecruitingDurham, NORTH%20CAROLINANCT05703178

Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia

The main goal of this clinical trial is to test benefits of completing online pain coping skills training program in women who have been diagnosed with stage I-III breast cancer, who have completed th...

452 participants
Northwestern University
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RecruitingDurham, NORTH%20CAROLINANCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingDurham, NORTH%20CAROLINANCT05735080

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio (Incyclix) is developing INX-315 as an oral, small molecule inhibitor of cyclin dependent kinase 2 (CDK2) for the treatment of human cancers. This first-in-human study is designed to eval...

150 participants
Incyclix Bio
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RecruitingDurham, NORTH%20CAROLINANCT06840483

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

This is a global, multicenter, open-label study that aims to assess the efficacy and safety of zelenectide pevedotin in participants with NECTIN4-amplified recurrent, unresectable, or metastatic breas...

66 participants
BicycleTx Limited
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RecruitingDurham, NORTH%20CAROLINANCT06176261

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

The purpose of this study is to test the safety and effectiveness of the study drug datopotamab deruxtecan in participants with metastatic breast cancer that has spread to the brain. The name of the ...

58 participants
Sarah Sammons, MD
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RecruitingDurham, NORTH%20CAROLINANCT04711824

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

This study is a Phase I/II study evaluating the safety and effectiveness of focused radiation therapy (radiosurgery) together with olaparib, followed by immunotherapy, for patients with brain metastas...

41 participants
Colette Shen
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RecruitingDurham, NORTH%20CAROLINANCT04837209

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

This research study is looking to see whether the combination of Dostarlimab and Niraparib plus Radiation Therapy (RT) is safe and effective in participants with metastatic triple negative breast canc...

32 participants
Massachusetts General Hospital
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About Breast Cancer Clinical Trials in Durham

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 7 breast cancer clinical trials recruiting participants in Durham, NORTH%20CAROLINA. These studies are seeking a combined 949 participants. Research is being sponsored by Northwestern University, Laura Huppert, MD, BA, Incyclix Bio and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Durham — FAQ

Are there breast cancer clinical trials in Durham?

Yes, there are 7 breast cancer clinical trials currently recruiting in Durham, NORTH%20CAROLINA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 7 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov