Fort Smith, ARKANSAS5 Active Studies

Rheumatoid Arthritis Clinical Trials in Fort Smith, ARKANSAS

Find 5 actively recruiting rheumatoid arthritis clinical trials in Fort Smith, ARKANSAS. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
3,004
Enrolling

Recruiting Rheumatoid Arthritis Studies in Fort Smith

RecruitingFort Smith, ARKANSASNCT06212999

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment wi...

960 participants
Incyte Corporation
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RecruitingFort Smith, ARKANSASNCT05156398

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years with episodic migraine....

640 participants
Pfizer
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RecruitingFort Smith, ARKANSASNCT06855498

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib....

600 participants
Incyte Corporation
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RecruitingFort Smith, ARKANSASNCT06799000

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis sup...

555 participants
Novartis Pharmaceuticals
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RecruitingFort Smith, ARKANSASNCT04628767

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

This phase II/III trial compares the effect of adding durvalumab to chemotherapy versus chemotherapy alone before surgery in treating patients with upper urinary tract cancer. Immunotherapy with monoc...

249 participants
National Cancer Institute (NCI)
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About Rheumatoid Arthritis Clinical Trials in Fort Smith

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 5 rheumatoid arthritis clinical trials recruiting participants in Fort Smith, ARKANSAS. These studies are seeking a combined 3,004 participants. Research is being sponsored by Incyte Corporation, Pfizer, Novartis Pharmaceuticals and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Fort Smith — FAQ

Are there rheumatoid arthritis clinical trials in Fort Smith?

Yes, there are 5 rheumatoid arthritis clinical trials currently recruiting in Fort Smith, ARKANSAS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Fort Smith?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Fort Smith research site will contact you about next steps.

Are clinical trials in Fort Smith free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Fort Smith studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 5 active trials in Fort Smith are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov