Fountain Valley, CALIFORNIA15 Active Studies

Psoriasis Clinical Trials in Fountain Valley, CALIFORNIA

Find 15 actively recruiting psoriasis clinical trials in Fountain Valley, CALIFORNIA. Connect with local research sites and explore new treatment options.

15
Active Trials
9
Sponsors
7,489
Enrolling

Recruiting Psoriasis Studies in Fountain Valley

RecruitingFountain Valley, CALIFORNIANCT06550076

A Study of TAK-279 in Participants With Moderate-to-Severe Plaque Psoriasis

The main aim of this study is to check the side effects of TAK-279 and how well it is tolerated in participants with moderate-to-severe plaque psoriasis. All participants will be assigned to study tr...

1,950 participants
Takeda
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RecruitingFountain Valley, CALIFORNIANCT06846541

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

The objective of the ESK-001-018 long term extension is to evaluate the safety and efficacy of ESK-001 over time. The scientific questions it aims to answer are: * How safe is taking ESK-001 long-ter...

1,680 participants
Alumis Inc
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RecruitingFountain Valley, CALIFORNIANCT06671483

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects the joints and skin in people who have psoriasis (PsO). The main aim of the study is to know how well zasocitinib (TAK-279) wo...

1,088 participants
Takeda
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RecruitingFountain Valley, CALIFORNIANCT04991116

Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis

An open label phase 3 study...

650 participants
Sun Pharmaceutical Industries Limited
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RecruitingFountain Valley, CALIFORNIANCT06973291

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

The main aim of this study is to assess whether zasocitinib works better than deucravacitinib in treating participants with moderate-to-severe plaque psoriasis. Participants will take one tablet dail...

600 participants
Takeda
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RecruitingFountain Valley, CALIFORNIANCT06979453

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

The purpose of this study is to evaluate the efficacy, safety, and drug levels of Deucravacitinib (BMS-986165) in adolescent participants with moderate to severe plaque psoriasis...

366 participants
Bristol-Myers Squibb
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RecruitingFountain Valley, CALIFORNIANCT06857942

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with moderate-to-severe plaque PsO and obesity o...

200 participants
Eli Lilly and Company
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RecruitingFountain Valley, CALIFORNIANCT06611163

A Study to Evaluate the Efficacy and Safety of Subcutaneous Tildrakizumab in Subjects With Moderate to Severe Genital Psoriasis.

Phase 3 study to evaluate the efficacy and safety of subcutaneous tildrakizumab in subjects with moderate to severe genital psoriasis....

192 participants
Sun Pharmaceutical Industries Limited
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RecruitingFountain Valley, CALIFORNIANCT06425549

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

The primary purpose of this study is to evaluate the efficacy of bimekizumab administered subcutaneously (sc) compared to active control (ustekinumab) in children and adolescents aged 6 to \<18 years ...

168 participants
UCB Biopharma SRL
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RecruitingFountain Valley, CALIFORNIANCT04123795

A Study to Evaluate the Pharmacokinetics, Safety, and Effectiveness of Certolizumab Pegol in Children With Moderate to Severe Chronic Plaque Psoriasis

The purpose of the study is to evaluate the pharmacokinetic (PK) of certolizumab pegol (CZP) in study participants aged 6 to 17 years with moderate to severe chronic plaque psoriasis (PSO) in order to...

150 participants
UCB Biopharma SRL
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RecruitingFountain Valley, CALIFORNIANCT03997786

A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque Psoriasis

The study has been designed with three components. Part A is an open label PK study followed by a randomized trial component (Part B) followed by open label Long Term Extension (LTE). The initial PK ...

130 participants
Sun Pharmaceutical Industries Limited
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RecruitingFountain Valley, CALIFORNIANCT05172726

Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis....

100 participants
Organon and Co
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RecruitingFountain Valley, CALIFORNIANCT06506916

A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis

The purpose of this study is to evaluate the effect of bimekizumab on gene expression biomarkers at Week 48 in a subset of study participants with moderate to severe plaque psoriasis (PSO) and moderat...

90 participants
UCB Biopharma SRL
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RecruitingFountain Valley, CALIFORNIANCT07090330

ORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque Psoriasis

This is a multicenter, randomized, double-blinded, placebo-controlled, proof-of-concept study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of ORKA-001 in adult participants wit...

80 participants
Oruka Therapeutics, Inc.
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RecruitingFountain Valley, CALIFORNIANCT03987763

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

This study is to evaluate the safety, the systemic exposure of halobetasol propionate (HP), and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-122 lotion...

45 participants
Bausch Health Americas, Inc.
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About Psoriasis Clinical Trials in Fountain Valley

Psoriasis is a chronic autoimmune skin condition affecting over 8 million Americans, causing cells to build up rapidly on the surface and forming red, scaly patches that can be itchy and painful. Plaque psoriasis accounts for about 80-90% of cases. While current treatments include topical therapies, phototherapy, and biologics like TNF inhibitors (adalimumab, etanercept) and IL-17/IL-23 inhibitors (secukinumab, guselkumab), clinical trials are testing next-generation oral treatments, TYK2 inhibitors, and combination approaches that may offer longer remission periods with fewer side effects. Patients with moderate-to-severe psoriasis who have not responded adequately to existing therapies are often sought for clinical trial enrollment.

There are currently 15 psoriasis clinical trials recruiting participants in Fountain Valley, CALIFORNIA. These studies are seeking a combined 7,489 participants. Research is being sponsored by Takeda, Alumis Inc, Sun Pharmaceutical Industries Limited and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Psoriasis Clinical Trials in Fountain Valley — FAQ

Are there psoriasis clinical trials in Fountain Valley?

Yes, there are 15 psoriasis clinical trials currently recruiting in Fountain Valley, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Fountain Valley?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Fountain Valley research site will contact you about next steps.

Are clinical trials in Fountain Valley free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Fountain Valley studies also compensate for your time and travel.

What psoriasis treatments are being tested?

The 15 active trials in Fountain Valley are testing new therapies including novel drugs, biologics, and treatment approaches for psoriasis.

Data updated March 2, 2026 from ClinicalTrials.gov