Fullerton, CALIFORNIA18 Active Studies

Ankylosing Spondylitis Clinical Trials in Fullerton, CALIFORNIA

Find 18 actively recruiting ankylosing spondylitis clinical trials in Fullerton, CALIFORNIA. Connect with local research sites and explore new treatment options.

18
Active Trials
12
Sponsors
17,768
Enrolling

Recruiting Ankylosing Spondylitis Studies in Fullerton

RecruitingFullerton, CALIFORNIANCT06742723

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

International, Multicenter, Double-Blind, Placebo-Controlled and Event-driven study to assess efficacy, safety and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and ca...

5,000 participants
AstraZeneca
View Study Details
RecruitingFullerton, CALIFORNIANCT06268873

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This study consists of a screening, a 4-week dapagliflo...

2,500 participants
AstraZeneca
View Study Details
RecruitingFullerton, CALIFORNIANCT06966700

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Researchers are looking for new ways to treat types of breast cancer that are both: * High-risk, which means the cancer may have a higher chance of getting worse or coming back after treatment * Earl...

2,400 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingFullerton, CALIFORNIANCT05097287

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

This is an interventional, randomized, parallel group, treatment, Phase 3b/4, double blind, 2-arm study to assess the effect of dupilumab compared to standard of care therapy on preventing or slowing ...

1,324 participants
Sanofi
View Study Details
RecruitingFullerton, CALIFORNIANCT06312176

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone rece...

1,200 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingFullerton, CALIFORNIANCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

This is a prospective, randomized, double-blinded, placebo-controlled, multi-center, Phase 3 study of GLSI-100 immunotherapy in HLA-A\*02 positive and HER2/neu positive subjects who are at high risk f...

750 participants
Greenwich LifeSciences, Inc.
View Study Details
RecruitingFullerton, CALIFORNIANCT04638647

Secukinumab Open Label Roll-over Extension Protocol

The purpose of this study is to assess long term safety in participants who have completed a Novartis trial with secukinumab, have been judged by the investigator to benefit from continued treatment w...

715 participants
Novartis Pharmaceuticals
View Study Details
RecruitingFullerton, CALIFORNIANCT06757634

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant and CDK4/6 Inhibitors for the treatment of patients with locally advanced o...

674 participants
Celcuity Inc
View Study Details
RecruitingFullerton, CALIFORNIANCT06976203

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease...

586 participants
Bristol-Myers Squibb
View Study Details
RecruitingFullerton, CALIFORNIANCT06346392

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

The purpose of this study is to measure the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ ade...

572 participants
AstraZeneca
View Study Details
RecruitingFullerton, CALIFORNIANCT06018337

A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-free survival (PFS) by blinded independent central ...

532 participants
DualityBio Inc.
View Study Details
RecruitingFullerton, CALIFORNIANCT06502366

A Study to Investigate the Effect on Lung Function of BDA Formulated With a New Propellant (HFO) Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed replacement propellant HFO compared with BDA delivered using the...

398 participants
AstraZeneca
View Study Details
RecruitingFullerton, CALIFORNIANCT05397639

Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, tolerability, and pharmacokinetics of masupirdine compared to placebo for the treatment of agitation in participants with dementia of the...

375 participants
Suven Life Sciences Limited
View Study Details
RecruitingFullerton, CALIFORNIANCT06072482

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

The primary objective of this study is to evaluate the long-term safety of avacopan in participants with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)....

300 participants
Amgen
View Study Details
RecruitingFullerton, CALIFORNIANCT06517758

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.

The study is a randomized, double-blind, placebo-controlled, multicenter, Phase III study, to evaluate efficacy, safety and tolerability of iptacopan in patients with AChR+ gMG who are on stable SOC t...

146 participants
Novartis Pharmaceuticals
View Study Details
RecruitingFullerton, CALIFORNIANCT06293365

Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two inje...

140 participants
Novartis Pharmaceuticals
View Study Details
RecruitingFullerton, CALIFORNIANCT04553770

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

This phase II trial investigates how well trastuzumab deruxtecan works alone or in combination with anastrozole in treating patients with HER2 low, hormone receptor positive breast cancer. Trastuzumab...

88 participants
Jonsson Comprehensive Cancer Center
View Study Details
RecruitingFullerton, CALIFORNIANCT05386108

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

This is a multi-site, global, open-label study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain metastases from estrogen receptor (ER)-pos...

68 participants
Stemline Therapeutics, Inc.
View Study Details

About Ankylosing Spondylitis Clinical Trials in Fullerton

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 18 ankylosing spondylitis clinical trials recruiting participants in Fullerton, CALIFORNIA. These studies are seeking a combined 17,768 participants. Research is being sponsored by AstraZeneca, Merck Sharp & Dohme LLC, Sanofi and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Fullerton — FAQ

Are there ankylosing spondylitis clinical trials in Fullerton?

Yes, there are 18 ankylosing spondylitis clinical trials currently recruiting in Fullerton, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Fullerton?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Fullerton research site will contact you about next steps.

Are clinical trials in Fullerton free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Fullerton studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 18 active trials in Fullerton are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov