12 Parkinsons Disease Clinical Trials in Gainesville, FL (2026)

Q: How do I join a clinical trial in Gainesville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Gainesville research site will contact you.

Recruiting Parkinsons Disease Studies in Gainesville

NCT06719583Recruiting

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The stud...

Gainesville, FL2,000 participantsMichael J. Fox Foundation for Parkinson's Research

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NCT02071134Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific's commercially available Vercise DBS System in the treatment of Parkinson's disease. ...

Gainesville, FL1,500 participantsBoston Scientific Corporation

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NCT04373317Recruiting

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Patients with Parkinson's disease (PD) sometimes experience symptoms affecting their movement, such as slowness, tremor, stiffness, and balance or walking problems. Many patients also have other sympt...

Gainesville, FLPHASE4358 participantsVA Office of Research and Development

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NCT06285643Recruiting

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered to the putamen in subjects with moderate Parkinson'...

Gainesville, FLPHASE2127 participantsAskBio Inc

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NCT07026734Recruiting

The Impact of Deep Brain Stimulation on Speech and Swallow Function in Parkinson Disease

Nearly one-million people in North America are now living with Parkinson's disease (PD), and that number is projected to rise to nearly 1.2 million by 2030. With advancements in neuromodulatory techno...

Gainesville, FLNA100 participantsUniversity of Florida

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NCT06911229Recruiting

Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease

Locomotor adaptation will be studied using an established split-belt treadmill paradigm, consisting of baseline (1:1 speed ratio), split-belt adaptation (2:1) and post-adaptation (1:1) walking. Split-...

Gainesville, FLNA60 participantsUniversity of Florida

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NCT07410598Recruiting

Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting

The primary objective of the proposed pilot study is to assess the safety and tolerability of active patterned Deep Brain Stimulation (pDBS) when administered in a home setting for patients with Parki...

Gainesville, FLNA60 participantsUniversity of Florida

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NCT07674264Recruiting

Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

Parkinsonism impairs upper airway and axial motor control, leading to disordered breathing, reduced speech volume, and ineffective cough. Symptoms are poorly addressed by current therapies. This rando...

Gainesville, FLNA32 participantsUniversity of Florida

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NCT07348705Recruiting

Electrophysiology-based DBS Programming for PD

Deep brain stimulation (DBS) effectively alleviates motor symptoms in Parkinson's disease (PD). However, current programming is manual and time-consuming. This study will evaluate physiology-based pro...

Gainesville, FLNA30 participantsUniversity of Florida

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NCT06635811Recruiting

Circadian Adaptive DBS in Essential Tremor

Deep brain stimulation (DBS) of the thalamus is an effective treatment for medically refractory essential tremor (ET). DBS involves delivering continuous stimulation to the brain through electrodes pe...

Gainesville, FLNA25 participantsUniversity of Florida

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NCT04212780Recruiting

Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor

This is a feasibility study based on physician-initiated Investigational Device Exemption (IDE) including intraoperative experiments and chronic testing of implanted dual thalamic DBS lead systems. Th...

Gainesville, FLNA10 participantsUniversity of Florida

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NCT07446192Recruiting

Magnetoencephalography (MEG) Pilot Study

The purpose of this research is to learn more about how the brain works in people with essential tremor, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). Essential tre...

Gainesville, FLNA10 participantsUniversity of Florida

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About Parkinsons Disease Clinical Trials in Gainesville

Parkinson's disease is a progressive nervous system disorder that affects movement, causing tremors, stiffness, and difficulty with balance. It results from the loss of dopamine-producing neurons in the brain. Treatment includes medications, deep brain stimulation, and emerging therapies targeting disease modification.

There are currently 12 parkinsons disease clinical trials recruiting participants in Gainesville, FL. These studies are seeking a combined 4,312 participants. Research is being sponsored by Michael J. Fox Foundation for Parkinson's Research, Boston Scientific Corporation, VA Office of Research and Development and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Parkinsons Disease Clinical Trials in Gainesville — FAQ

Are there parkinsons disease clinical trials in Gainesville?

Yes, there are 12 parkinsons disease clinical trials currently recruiting in Gainesville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Gainesville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Gainesville research site will contact you about next steps.

Are clinical trials in Gainesville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Gainesville studies also compensate for your time and travel.

What parkinsons disease treatments are being tested?

The 12 active trials in Gainesville are testing new therapies including novel drugs, biologics, and treatment approaches for parkinsons disease.

Data updated July 18, 2026 from ClinicalTrials.gov