Garden Grove, CA9 Active Studies

Rheumatoid Arthritis Clinical Trials in Garden Grove, CA

Find 9 actively recruiting rheumatoid arthritis clinical trials in Garden Grove, CA. Connect with local research sites and explore new treatment options.

9
Active Trials
8
Sponsors
1,322
Enrolling

Recruiting Rheumatoid Arthritis Studies in Garden Grove

RecruitingGarden Grove, CANCT06588855

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with mo...

350 participants
Hoffmann-La Roche
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RecruitingGarden Grove, CANCT06290934

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if GS-1427 is effective in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treate...

228 participants
Gilead Sciences
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RecruitingGarden Grove, CANCT06029972

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will comp...

176 participants
Gilead Sciences
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RecruitingGarden Grove, CANCT06598943

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC)....

140 participants
Eli Lilly and Company
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RecruitingGarden Grove, CANCT06127043

A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)...

132 participants
AnaptysBio, Inc.
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RecruitingGarden Grove, CANCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

120 participants
Bristol-Myers Squibb
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RecruitingGarden Grove, CANCT06100289

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

The main aim of this study is to learn how the body of a child or teenager with moderately to severely active ulcerative colitis (UC) or Crohn's disease (CD) processes vedolizumab (pharmacokinetics) g...

70 participants
Takeda
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RecruitingGarden Grove, CANCT04314375

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

This is a randomized, double-blind, placebo-controlled, multicenter, study to evaluate the efficacy, safety, and pharmacokinetics (PK) of budesonide extended-release tablets for the induction of remis...

70 participants
Bausch Health Americas, Inc.
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RecruitingGarden Grove, CANCT05287126

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years ...

36 participants
Pfizer
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About Rheumatoid Arthritis Clinical Trials in Garden Grove

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 9 rheumatoid arthritis clinical trials recruiting participants in Garden Grove, CA. These studies are seeking a combined 1,322 participants. Research is being sponsored by Hoffmann-La Roche, Gilead Sciences, Eli Lilly and Company and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Garden Grove — FAQ

Are there rheumatoid arthritis clinical trials in Garden Grove?

Yes, there are 9 rheumatoid arthritis clinical trials currently recruiting in Garden Grove, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Garden Grove?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Garden Grove research site will contact you about next steps.

Are clinical trials in Garden Grove free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Garden Grove studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 9 active trials in Garden Grove are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov