Grand Rapids, MICHIGAN10 Active Studies

Pulmonary Hypertension Clinical Trials in Grand Rapids, MICHIGAN

Find 10 actively recruiting pulmonary hypertension clinical trials in Grand Rapids, MICHIGAN. Connect with local research sites and explore new treatment options.

10
Active Trials
6
Sponsors
2,195
Enrolling

Recruiting Pulmonary Hypertension Studies in Grand Rapids

RecruitingGrand Rapids, MICHIGANNCT06717347

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

The purpose of this study is to evaluate if zilovertamab vedotin with standard treatment can help people live longer without the cancer growing or spreading than people who receive standard treatment ...

1,046 participants
Merck Sharp & Dohme LLC
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RecruitingGrand Rapids, MICHIGANNCT04104776

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

The purpose of this open-label, first-in-human (FIH) trial is to evaluate the safety, tolerability, and preliminary clinical activity of Tulmimetostat as a monotherapy in patients with advanced solid ...

275 participants
Novartis Pharmaceuticals
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RecruitingGrand Rapids, MICHIGANNCT05826535

Study of LYL314 in Aggressive Large B-Cell Lymphoma

This is a Phase 1/2, multi-center, open-label study evaluating the safety and efficacy of LYL314, a dual-targeting chimeric antigen receptor (CAR) targeting cluster of differentiation (CD)19 and CD20 ...

270 participants
Lyell Immunopharma, Inc.
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RecruitingGrand Rapids, MICHIGANNCT06846671

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

The purpose of this study is to investigate the efficacy and safety of BGB-16673 compared with investigator's choice (idelalisib plus rituximab \[for CLL only\] or bendamustine plus rituximab or venet...

250 participants
BeiGene
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RecruitingGrand Rapids, MICHIGANNCT06469944

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

This is a phase 1/2, multicenter, open-label umbrella platform study that will evaluate the safety and tolerability of sacituzumab tirumotecan with pembrolizumab and fluoropyrimidine chemotherapy for ...

130 participants
Merck Sharp & Dohme LLC
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RecruitingGrand Rapids, MICHIGANNCT06445972

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

This is a phase 1/2 multicenter, open-label umbrella platform study that will evaluate the safety and efficacy of sacituzumab tirumotecan (MK-2870) plus paclitaxel versus ramucirumab plus paclitaxel, ...

90 participants
Merck Sharp & Dohme LLC
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RecruitingGrand Rapids, MICHIGANNCT06450639

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

The purpose of this study is to assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of satralizumab, a humanized anti-interleukin-6 receptor (aIL-6R) monoclonal antibody, in a...

50 participants
Hoffmann-La Roche
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RecruitingGrand Rapids, MICHIGANNCT05861999

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered in pediatric participants with SMA and 2 SMN2 copies who previously rec...

28 participants
Hoffmann-La Roche
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RecruitingGrand Rapids, MICHIGANNCT05861986

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered as an early intervention in pediatric participants with spinal muscular...

28 participants
Hoffmann-La Roche
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RecruitingGrand Rapids, MICHIGANNCT07024693

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

The purpose of this study is to evaluate the pharmacodynamics, safety, and tolerability of DT-168 Ophthalmic Solution in pre-keratoplasty patients with Fuchs endothelial corneal dystrophy....

28 participants
Design Therapeutics, Inc.
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About Pulmonary Hypertension Clinical Trials in Grand Rapids

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 10 pulmonary hypertension clinical trials recruiting participants in Grand Rapids, MICHIGAN. These studies are seeking a combined 2,195 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Novartis Pharmaceuticals, Lyell Immunopharma, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Grand Rapids — FAQ

Are there pulmonary hypertension clinical trials in Grand Rapids?

Yes, there are 10 pulmonary hypertension clinical trials currently recruiting in Grand Rapids, MICHIGAN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Grand Rapids?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Grand Rapids research site will contact you about next steps.

Are clinical trials in Grand Rapids free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Grand Rapids studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 10 active trials in Grand Rapids are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov