Hartford, CT19 Active Studies

Ankylosing Spondylitis Clinical Trials in Hartford, CT

Find 19 actively recruiting ankylosing spondylitis clinical trials in Hartford, CT. Connect with local research sites and explore new treatment options.

19
Active Trials
12
Sponsors
4,505
Enrolling

Recruiting Ankylosing Spondylitis Studies in Hartford

RecruitingHartford, CTNCT05781152

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pai...

900 participants
Connecticut Children's Medical Center
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RecruitingHartford, CTNCT04893109

ATEMPT 2.0: Adjuvant T-DM1 vs TH

This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two different combination of HER2-directed therapies as ...

500 participants
Dana-Farber Cancer Institute
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RecruitingHartford, CTNCT02559778

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled ...

500 participants
Giselle Sholler
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RecruitingHartford, CTNCT02679144

Neuroblastoma Maintenance Therapy Trial

Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluo...

441 participants
Giselle Sholler
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RecruitingHartford, CTNCT05949684

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

The purpose of the study is to compare the efficacy and safety of Luspatercept vs epoetin alfa in the treatment of anemia in adults due to IPSS-R very low, low, intermediate-risk MDS in ESA-naïve part...

360 participants
Bristol-Myers Squibb
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RecruitingHartford, CTNCT06901505

To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

This is a multi-center, randomized (1:1), open-label, active-controlled, pragmatic study of the efficacy of vadadustat administered three times a week compared to standard of care erythropoiesis-stimu...

350 participants
Akebia Therapeutics
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RecruitingHartford, CTNCT05789485

A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

The purpose of this study is to find the level of aerobic exercise (AT) that is practical, is safe, and has positive effects on the body that may reduce the side effects of therapy. The study will als...

216 participants
Memorial Sloan Kettering Cancer Center
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RecruitingHartford, CTNCT04844606

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

150 participants
Eli Lilly and Company
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RecruitingHartford, CTNCT03808337

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

This study is being done to determine if stereotactic body radiotherapy (SBRT) when delivered to all sites of disease in participants with 1-5 metastases will increase the length of time before partic...

145 participants
Memorial Sloan Kettering Cancer Center
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RecruitingHartford, CTNCT04301843

Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study in combination with etoposide for subjects with relapsed/refractory neuroblastoma....

131 participants
Giselle Sholler
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RecruitingHartford, CTNCT05898087

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who unde...

128 participants
Connecticut Children's Medical Center
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RecruitingHartford, CTNCT05923073

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants with Crohn's Disease (CD) at the end of maintenance therapy (Week 52) among partic...

120 participants
Janssen Research & Development, LLC
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RecruitingHartford, CTNCT03847467

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

Randomized, placebo-controlled dose-ranging study of 2'-FL in IBD, Crohn's Disease (CD) and ulcerative colitis (UC). The overarching hypothesis is that 2'-FL supplementation in IBD will be safe and we...

116 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingHartford, CTNCT06332534

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms includ...

110 participants
AbbVie
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RecruitingHartford, CTNCT05489887

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therap...

93 participants
Giselle Sholler
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RecruitingHartford, CTNCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

90 participants
Eli Lilly and Company
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RecruitingHartford, CTNCT03606967

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

This phase II trial studies how well nab-paclitaxel, durvalumab, and tremelimumab with or without personalized synthetic long peptide vaccine (neoantigen vaccine) works in treating patients with tripl...

70 participants
National Cancer Institute (NCI)
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RecruitingHartford, CTNCT05419076

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

The purpose of the study is to see if stereotactic radiosurgery/SRS is an effective treatment for people with a new diagnosis of brain metastases from small cell lung cancer/SCLC....

62 participants
Memorial Sloan Kettering Cancer Center
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RecruitingHartford, CTNCT06701812

Digoxin Medulloblastoma Study

The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients....

23 participants
H. Lee Moffitt Cancer Center and Research Institute
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About Ankylosing Spondylitis Clinical Trials in Hartford

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 19 ankylosing spondylitis clinical trials recruiting participants in Hartford, CT. These studies are seeking a combined 4,505 participants. Research is being sponsored by Connecticut Children's Medical Center, Dana-Farber Cancer Institute, Giselle Sholler and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Hartford — FAQ

Are there ankylosing spondylitis clinical trials in Hartford?

Yes, there are 19 ankylosing spondylitis clinical trials currently recruiting in Hartford, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Hartford?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Hartford research site will contact you about next steps.

Are clinical trials in Hartford free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Hartford studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 19 active trials in Hartford are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated March 2, 2026 from ClinicalTrials.gov