Houston, TEXAS12 Active Studies

Acute Myeloid Leukemia Clinical Trials in Houston, TEXAS

Find 12 actively recruiting acute myeloid leukemia clinical trials in Houston, TEXAS. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
1,131
Enrolling

Recruiting Acute Myeloid Leukemia Studies in Houston

RecruitingHouston, TEXASNCT05732103

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

The goal of this phase 1/2 multicenter, open-label, single-arm dose escalation and expansion study is to assess the safety, tolerability, pharmacokinetic and pharmacodynamic profile of CTX-712 in pati...

225 participants
Chordia Therapeutics, Inc.
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RecruitingHouston, TEXASNCT04588922

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies

SLS009 (formerly GFH009) is a potent and highly selective CDK9 inhibitor. In this study the safety, tolerability, and antitumor activity of single agent SLS009 are assessed in two dose escalation grou...

160 participants
Sellas Life Sciences Group
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RecruitingHouston, TEXASNCT06969430

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

The primary purpose of Phase 1 is to assess the doses studied under Phase 1 (Dose Escalation) Arm A and identify the recommended dose (RD) for further development (Dose optimization). The primary obj...

134 participants
Debiopharm International SA
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RecruitingHouston, TEXASNCT06824168

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

This clinical two-arm trial is designed to evaluate two doses of quizartinib as maintenance therapy after induction/consolidation in participants with FMS-like tyrosine kinase 3 (FLT3)-internal tandem...

130 participants
Daiichi Sankyo
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RecruitingHouston, TEXASNCT02781883

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

The primary objectives of this study are to assess: (1) whether the combination of BP1001 plus venetoclax plus decitabine provides greater efficacy (Complete Remission \[CR\], Complete Remission with ...

108 participants
Bio-Path Holdings, Inc.
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RecruitingHouston, TEXASNCT04626024

Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population

This is a single-arm, phase II study to evaluate safety and efficacy of tyrosine kinase inhibitor (TKI) cessation for chronic myeloid leukemia (CML) patients with stable molecular response in a real w...

100 participants
Baylor College of Medicine
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RecruitingHouston, TEXASNCT05503355

A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML

An open label multi centre study to assess the safety and efficacy of BST-236 in combination with venetoclax in adult patients unfit for standard therapy with newly diagnosed Acute Myeloid Leukemia (A...

80 participants
BioSight Ltd.
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RecruitingHouston, TEXASNCT04358393

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

This is a two Part study in patients with relapsed/refractory acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML), or high risk myelodysplastic syndrome (MDS) that will initially eval...

69 participants
Ascentage Pharma Group Inc.
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RecruitingHouston, TEXASNCT06680752

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

This is a phase I/2, interventional, open-label, multicenter study to assess the safety and efficacy of ARD103 in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic syndrom...

49 participants
ARCE Therapeutics, Inc.
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RecruitingHouston, TEXASNCT04925479

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

The aim of this study is to support development of asciminib in the pediatric population (1 to \<18 years) previously treated with one or more TKIs. Full extrapolation of the efficacy of asciminib fro...

44 participants
Novartis Pharmaceuticals
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RecruitingHouston, TEXASNCT04964518

A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

This is a Phase Ib/II, open-label, multi-center study evaluating the safety, tolerability, efficacy and PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The st...

24 participants
Ascentage Pharma Group Inc.
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RecruitingHouston, TEXASNCT06284486

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

To learn if the combination of venetoclax and revumenib can help to control MRD-positive AML....

8 participants
M.D. Anderson Cancer Center
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About Acute Myeloid Leukemia Clinical Trials in Houston

Acute myeloid leukemia (AML) is a fast-growing cancer of the blood and bone marrow characterized by abnormal myeloid cells. It is the most common acute leukemia in adults. Treatment typically includes intensive chemotherapy and may involve stem cell transplant.

There are currently 12 acute myeloid leukemia clinical trials recruiting participants in Houston, TEXAS. These studies are seeking a combined 1,131 participants. Research is being sponsored by Chordia Therapeutics, Inc., Sellas Life Sciences Group, Debiopharm International SA and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Acute Myeloid Leukemia Clinical Trials in Houston — FAQ

Are there acute myeloid leukemia clinical trials in Houston?

Yes, there are 12 acute myeloid leukemia clinical trials currently recruiting in Houston, TEXAS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Houston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Houston research site will contact you about next steps.

Are clinical trials in Houston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Houston studies also compensate for your time and travel.

What acute myeloid leukemia treatments are being tested?

The 12 active trials in Houston are testing new therapies including novel drugs, biologics, and treatment approaches for acute myeloid leukemia.

Data updated March 2, 2026 from ClinicalTrials.gov