Huntington Beach, CALIFORNIA8 Active Studies

Macular Degeneration Clinical Trials in Huntington Beach, CALIFORNIA

Find 8 actively recruiting macular degeneration clinical trials in Huntington Beach, CALIFORNIA. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
2,937
Enrolling

Recruiting Macular Degeneration Studies in Huntington Beach

RecruitingHuntington Beach, CALIFORNIANCT06541704

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

This study is researching experimental (study) drugs called pozelimab and cemdisiran. The study is focused on participants who have Geographic Atrophy (GA) caused by Age-related Macular Degeneration (...

975 participants
Regeneron Pharmaceuticals
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT04704921

Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD or nAMD). Wet AMD is character...

630 participants
AbbVie
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT06864988

4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration...

400 participants
4D Molecular Therapeutics
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT06373731

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

The goal of this clinical trial is to evaluate the efficacy, safety and pharmacokinetics of elamipretide in subjects with dry age-related macular degeneration (AMD). The main questions it aims to answ...

360 participants
Stealth BioTherapeutics Inc.
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT04853251

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W)....

188 participants
Genentech, Inc.
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT06116890

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

The purpose of this study is to evaluate efficacy and safety of KHK4951 eye drops in patients with nAMD....

180 participants
Kyowa Kirin Co., Ltd.
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT06722157

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan...

180 participants
Boehringer Ingelheim
View Study Details
RecruitingHuntington Beach, CALIFORNIANCT06557460

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

This is a Phase IIb randomized, clinical trial designed to assess the safety and efficacy of unilateral implantation of the CPCB-RPE1 implant in subjects with geographic atrophy involving the fovea. ...

24 participants
Regenerative Patch Technologies, LLC
View Study Details

About Macular Degeneration Clinical Trials in Huntington Beach

Age-related macular degeneration (AMD) is the leading cause of severe vision loss in Americans over 50, affecting over 11 million people. Wet (neovascular) AMD involves abnormal blood vessel growth under the retina, while dry AMD involves gradual thinning of the macula and accumulation of drusen deposits. Current treatment for wet AMD relies on anti-VEGF injections (ranibizumab, aflibercept, faricimab), with newer high-dose and extended-interval formulations reducing treatment burden. For geographic atrophy (advanced dry AMD), complement inhibitors like pegcetacoplan (Syfovre) represent the first approved treatments. Clinical trials are testing gene therapies, implantable drug delivery systems, stem cell therapies, and novel targets beyond VEGF for both wet and dry AMD.

There are currently 8 macular degeneration clinical trials recruiting participants in Huntington Beach, CALIFORNIA. These studies are seeking a combined 2,937 participants. Research is being sponsored by Regeneron Pharmaceuticals, AbbVie, 4D Molecular Therapeutics and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Macular Degeneration Clinical Trials in Huntington Beach — FAQ

Are there macular degeneration clinical trials in Huntington Beach?

Yes, there are 8 macular degeneration clinical trials currently recruiting in Huntington Beach, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Huntington Beach?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Huntington Beach research site will contact you about next steps.

Are clinical trials in Huntington Beach free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Huntington Beach studies also compensate for your time and travel.

What macular degeneration treatments are being tested?

The 8 active trials in Huntington Beach are testing new therapies including novel drugs, biologics, and treatment approaches for macular degeneration.

Data updated March 2, 2026 from ClinicalTrials.gov