9 Crohns Disease Clinical Trials in Indianapolis, IN (2026)

Q: How do I join a clinical trial in Indianapolis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you.

Recruiting Crohns Disease Studies in Indianapolis

NCT05781152Recruiting

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pai...

Indianapolis, INPHASE4900 participantsConnecticut Children's Medical Center

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NCT06227910Recruiting

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

Indianapolis, INPHASE3396 participantsTakeda

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NCT06663332Recruiting

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

The purpose of this study is to evaluate long-term safety of subcutaneous guselkumab in pediatric participants with moderately to severely active ulcerative colitis, or moderately to severely active C...

Indianapolis, INPHASE3196 participantsJanssen Research & Development, LLC

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NCT05660746Recruiting

Precise Infliximab Exposure and Pharmacodynamic Control

Approximately 3 million people in the United States are living with inflammatory bowel disease, which includes Crohn's Disease (CD). There are limited treatment options approved for use in children an...

Indianapolis, INPHASE2180 participantsChildren's Hospital Medical Center, Cincinnati

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NCT05923073Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants with Crohn's Disease (CD) at the end of maintenance therapy (Week 52) among partic...

Indianapolis, INPHASE3120 participantsJanssen Research & Development, LLC

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NCT04779320Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with vedoliz...

Indianapolis, INPHASE3120 participantsTakeda

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NCT05995353Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This study will assess the pharmacokinetics, ...

Indianapolis, INPHASE3110 participantsAbbVie

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NCT06332534Recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms includ...

Indianapolis, INPHASE3110 participantsAbbVie

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NCT05509777Recruiting

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

Indianapolis, INPHASE390 participantsEli Lilly and Company

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About Crohns Disease Clinical Trials in Indianapolis

Crohn's disease is a chronic inflammatory bowel disease that causes inflammation anywhere in the digestive tract, most commonly in the small intestine and colon. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 9 crohns disease clinical trials recruiting participants in Indianapolis, IN. These studies are seeking a combined 2,222 participants. Research is being sponsored by Connecticut Children's Medical Center, Takeda, Janssen Research & Development, LLC and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Crohns Disease Clinical Trials in Indianapolis — FAQ

Are there crohns disease clinical trials in Indianapolis?

Yes, there are 9 crohns disease clinical trials currently recruiting in Indianapolis, IN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What crohns disease treatments are being tested?

The 9 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for crohns disease.

Data updated July 20, 2026 from ClinicalTrials.gov